MC1018A1 - Procédé de préparation de nouvelles thiaprostaglandines - Google Patents

Procédé de préparation de nouvelles thiaprostaglandines

Info

Publication number
MC1018A1
MC1018A1 MC1114A MC1114A MC1018A1 MC 1018 A1 MC1018 A1 MC 1018A1 MC 1114 A MC1114 A MC 1114A MC 1114 A MC1114 A MC 1114A MC 1018 A1 MC1018 A1 MC 1018A1
Authority
MC
Monaco
Prior art keywords
thiaprostaglandins
novel
preparation
novel thiaprostaglandins
Prior art date
Application number
MC1114A
Other languages
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of MC1018A1 publication Critical patent/MC1018A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/32—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
    • C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms
MC1114A 1973-05-18 1974-05-15 Procédé de préparation de nouvelles thiaprostaglandines MC1018A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US361752A US3881017A (en) 1973-05-18 1973-05-18 9-Thiaprostaglandin compositions

Publications (1)

Publication Number Publication Date
MC1018A1 true MC1018A1 (fr) 1975-02-28

Family

ID=23423319

Family Applications (1)

Application Number Title Priority Date Filing Date
MC1114A MC1018A1 (fr) 1973-05-18 1974-05-15 Procédé de préparation de nouvelles thiaprostaglandines

Country Status (11)

Country Link
US (1) US3881017A (fr)
AR (5) AR207448A1 (fr)
CS (4) CS180047B2 (fr)
ES (1) ES426425A1 (fr)
FI (1) FI149274A (fr)
HU (1) HU172465B (fr)
IE (1) IE39573B1 (fr)
IL (1) IL44770A (fr)
MC (1) MC1018A1 (fr)
PL (2) PL98958B1 (fr)
ZA (2) ZA742445B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018802A (en) * 1975-04-09 1977-04-19 Merck & Co., Inc. 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins and processes
US4130566A (en) * 1977-10-27 1978-12-19 Sumitomo Chemical Company, Limited Process for producing 5-carboxy-2-acetylthiophene
US4258199A (en) * 1978-03-13 1981-03-24 Research Corporation Method for preparing cyclic ethers and thioethers including oxygen isomers and sulfur analogs of prostacyclin
US4291166A (en) * 1978-03-13 1981-09-22 Research Corporation Pharmaceutically active 6,9-thiaprostacyclin analogs and derivatives thereof
US4256878A (en) * 1978-05-11 1981-03-17 Hoffmann-La Roche Inc. Polyene compounds
US4230872A (en) * 1978-05-11 1980-10-28 Hoffmann-La Roche Inc. Polyene compounds
US5371096A (en) * 1993-08-27 1994-12-06 Ciba-Geigy Corporation (3-pyridyl)tetrafuran-2-yl substituted carboxylic acids
MX2009011165A (es) * 2007-04-18 2009-12-09 Cornerstone Pharmaceuticals In Formulaciones farmaceuticas que contienen derivados del acido lipoico.
US8263653B2 (en) * 2007-04-18 2012-09-11 Cornerstone Pharmaceuticals, Inc. Pharmaceutical formulations containing lipoic acid derivatives
EP2139321B1 (fr) 2007-04-18 2013-11-06 Cornerstone Pharmaceuticals, Inc. Dérivés d'acide lipoïque
CA2965898C (fr) 2014-06-19 2021-07-06 Robert Shorr Analogues d'acides gras
ES2819175T3 (es) 2014-06-19 2021-04-15 Rafael Pharmaceuticals Inc Compuestos farmacéuticos

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3691202A (en) * 1968-10-25 1972-09-12 Ici Ltd Phenyl-thienyl- and phenyl-furyl malonic acid derivatives

Also Published As

Publication number Publication date
PL98130B1 (pl) 1978-04-29
CS180048B2 (en) 1977-12-30
CS180011B2 (en) 1977-12-30
AR209769A1 (es) 1977-05-31
CS180047B2 (en) 1977-12-30
ES426425A1 (es) 1976-07-01
ZA743150B (en) 1975-05-28
HU172465B (hu) 1978-09-28
CS180046B2 (en) 1977-12-30
AR207448A1 (es) 1976-10-08
AR208350A1 (es) 1976-12-20
IL44770A0 (en) 1974-07-31
ZA742445B (en) 1975-05-28
AR205275A1 (es) 1976-04-21
IE39573L (en) 1974-11-18
FI149274A (fr) 1974-11-19
PL98958B1 (pl) 1978-06-30
US3881017A (en) 1975-04-29
AR205464A1 (es) 1976-05-07
IE39573B1 (en) 1978-11-08
IL44770A (en) 1977-10-31

Similar Documents

Publication Publication Date Title
OA04987A (fr) Procédé de préparation d'amibes tertiaires cycliques.
RO69607A (fr) Procede pour preparer des 3-carbamoiloxymethylcephalosporines
OA05445A (fr) Procédé de préparation de nouvelles pyrimidones.
CH537921A (fr) Procédé de préparation de nouvelles p-halogéno-phényl-2-pyrrolidinones
CH542199A (fr) Procédé pour la préparation de nouvelles aminophénylalkylamines hétérocycliques
OA04809A (fr) Procédé de préparation d'a-aminoacyl-3-halocépha-losporines.
OA04511A (fr) Procédé de préparation de 3-hydroxycéphalosporines.
MC1018A1 (fr) Procédé de préparation de nouvelles thiaprostaglandines
CH532034A (fr) Procédé de préparation de dibenzo-oxépine-spiro-dioxolannes substiués
OA05096A (fr) Procédé de préparation de composés hétérocycliques.
CH535227A (fr) Procédé de préparation de bis-chromones
OA04525A (fr) Procédé de préparation de nouvelles diazépines.
BE829779A (fr) Procede de preparation de pyrazolo-benzazepines
BE832428A (fr) Procede de preparation de 2-methyl-tetra-hydropyrimidines 1- substituees
OA04641A (fr) Prcédé de préparation de 3-fluorocéphalosporines.
OA04688A (fr) Procédé de préparation de 3-halocéphalosporines.
CH522577A (fr) Procédé de préparation de 5-cyclohexadécène-1-one
CH540922A (fr) Procédé de préparation de 2-phényl-3-aminoacyl-benzo-thiazolines
RO69264A (fr) Procede pour la preparation des alpha-amino-alcools
CH523226A (fr) Procédé de préparation d'a-halogénophénylacétamides
CH529781A (fr) Procédé de préparation de nouvelles quinazolines
OA05390A (fr) Procédé pour la préparation de composition anthelmintique.
CH535800A (fr) Procédé de préparation de nouvelles compositions polymères
CH517765A (fr) Procédé de préparation d'ortho-sulfobenzimides
OA04254A (fr) Nouveau procédé de préparation de nouvelles pentanones polycyliques.

Legal Events

Date Code Title Description
YP Annual fee paid