AR205275A1 - Procedimiento para obtener nuevos acidos 7 - (3alpha - (3 - hidroxi - 3 - aquil - 1 propenil - ) - 4 - hidroxi - tetrahidro - 2beta - tienil) heptanicos o -5 - heptenicos - Google Patents

Procedimiento para obtener nuevos acidos 7 - (3alpha - (3 - hidroxi - 3 - aquil - 1 propenil - ) - 4 - hidroxi - tetrahidro - 2beta - tienil) heptanicos o -5 - heptenicos

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Publication number
AR205275A1
AR205275A1 AR258988A AR25898875A AR205275A1 AR 205275 A1 AR205275 A1 AR 205275A1 AR 258988 A AR258988 A AR 258988A AR 25898875 A AR25898875 A AR 25898875A AR 205275 A1 AR205275 A1 AR 205275A1
Authority
AR
Argentina
Prior art keywords
hydroxy
heptenics
heptanics
aquyl
2beta
Prior art date
Application number
AR258988A
Other languages
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of AR205275A1 publication Critical patent/AR205275A1/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/32Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/46Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
    • C07D333/48Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AR258988A 1973-05-18 1975-01-01 Procedimiento para obtener nuevos acidos 7 - (3alpha - (3 - hidroxi - 3 - aquil - 1 propenil - ) - 4 - hidroxi - tetrahidro - 2beta - tienil) heptanicos o -5 - heptenicos AR205275A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US361752A US3881017A (en) 1973-05-18 1973-05-18 9-Thiaprostaglandin compositions

Publications (1)

Publication Number Publication Date
AR205275A1 true AR205275A1 (es) 1976-04-21

Family

ID=23423319

Family Applications (5)

Application Number Title Priority Date Filing Date
AR253832A AR207448A1 (es) 1973-05-18 1974-01-01 Procedimiento para elaborar nuevos acidos de 7-(3alpha-(3-hidroxi-3-alquilpropil)o-1-propenil o-1-propinil)-4-hidroxi-tetrahidro-2beta-tienil)-heptanicos o 5-heptenicos
AR258988A AR205275A1 (es) 1973-05-18 1975-01-01 Procedimiento para obtener nuevos acidos 7 - (3alpha - (3 - hidroxi - 3 - aquil - 1 propenil - ) - 4 - hidroxi - tetrahidro - 2beta - tienil) heptanicos o -5 - heptenicos
AR258990A AR205464A1 (es) 1973-05-18 1975-01-01 Procedimiento para la elaboracion de nuevos acidos 7-(3alpha-(3-hidroxi-3alquilpropil 6 -i-propenil 6 i-propinil) - 4 - hidroxitetrahidro-2beta-tienil) - heptanicos 6 -5-heptenicos
AR258989A AR209769A1 (es) 1973-05-18 1975-05-28 Procedimiento para la elaboracion de nuevos acidos 7-(3-(3-hidroxi -3- alquil -1- propenil)-4- hidroxi-tetrahidro-2 -tienil)heptanicos) o -5-heptenicos
AR262002A AR208350A1 (es) 1973-05-18 1976-01-01 Procedimiento para la elaboracion de nuevos acidos 7-(3alpha-(3-hidroxi-3-alquil-1-propenil)-4-hidroxi-tetrahidro-2beta-tienil)-heptanicos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AR253832A AR207448A1 (es) 1973-05-18 1974-01-01 Procedimiento para elaborar nuevos acidos de 7-(3alpha-(3-hidroxi-3-alquilpropil)o-1-propenil o-1-propinil)-4-hidroxi-tetrahidro-2beta-tienil)-heptanicos o 5-heptenicos

Family Applications After (3)

Application Number Title Priority Date Filing Date
AR258990A AR205464A1 (es) 1973-05-18 1975-01-01 Procedimiento para la elaboracion de nuevos acidos 7-(3alpha-(3-hidroxi-3alquilpropil 6 -i-propenil 6 i-propinil) - 4 - hidroxitetrahidro-2beta-tienil) - heptanicos 6 -5-heptenicos
AR258989A AR209769A1 (es) 1973-05-18 1975-05-28 Procedimiento para la elaboracion de nuevos acidos 7-(3-(3-hidroxi -3- alquil -1- propenil)-4- hidroxi-tetrahidro-2 -tienil)heptanicos) o -5-heptenicos
AR262002A AR208350A1 (es) 1973-05-18 1976-01-01 Procedimiento para la elaboracion de nuevos acidos 7-(3alpha-(3-hidroxi-3-alquil-1-propenil)-4-hidroxi-tetrahidro-2beta-tienil)-heptanicos

Country Status (11)

Country Link
US (1) US3881017A (es)
AR (5) AR207448A1 (es)
CS (4) CS180048B2 (es)
ES (1) ES426425A1 (es)
FI (1) FI149274A (es)
HU (1) HU172465B (es)
IE (1) IE39573B1 (es)
IL (1) IL44770A (es)
MC (1) MC1018A1 (es)
PL (2) PL98958B1 (es)
ZA (2) ZA742445B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018802A (en) * 1975-04-09 1977-04-19 Merck & Co., Inc. 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins and processes
US4130566A (en) * 1977-10-27 1978-12-19 Sumitomo Chemical Company, Limited Process for producing 5-carboxy-2-acetylthiophene
US4291166A (en) * 1978-03-13 1981-09-22 Research Corporation Pharmaceutically active 6,9-thiaprostacyclin analogs and derivatives thereof
US4258199A (en) * 1978-03-13 1981-03-24 Research Corporation Method for preparing cyclic ethers and thioethers including oxygen isomers and sulfur analogs of prostacyclin
US4256878A (en) * 1978-05-11 1981-03-17 Hoffmann-La Roche Inc. Polyene compounds
US4230872A (en) * 1978-05-11 1980-10-28 Hoffmann-La Roche Inc. Polyene compounds
US5371096A (en) * 1993-08-27 1994-12-06 Ciba-Geigy Corporation (3-pyridyl)tetrafuran-2-yl substituted carboxylic acids
JP5412423B2 (ja) 2007-04-18 2014-02-12 コーナーストーン ファーマシューティカルズ,インコーポレーテッド リポ酸誘導体
US8263653B2 (en) * 2007-04-18 2012-09-11 Cornerstone Pharmaceuticals, Inc. Pharmaceutical formulations containing lipoic acid derivatives
BRPI0810439B1 (pt) 2007-04-18 2021-06-29 Cornerstone Pharmaceuticals, Inc. Formulações farmacêuticas contendo derivados de ácido lipóico
CA2965963A1 (en) 2014-06-19 2015-12-23 Robert Shorr Lipoic acid derivatives for pharmaceutical use
EP3188726B1 (en) 2014-06-19 2019-08-07 Rafael Pharmaceuticals, Inc. Pharmaceutical compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3691202A (en) * 1968-10-25 1972-09-12 Ici Ltd Phenyl-thienyl- and phenyl-furyl malonic acid derivatives

Also Published As

Publication number Publication date
ZA743150B (en) 1975-05-28
IL44770A0 (en) 1974-07-31
CS180046B2 (en) 1977-12-30
IL44770A (en) 1977-10-31
CS180047B2 (en) 1977-12-30
ES426425A1 (es) 1976-07-01
MC1018A1 (fr) 1975-02-28
IE39573L (en) 1974-11-18
AR205464A1 (es) 1976-05-07
PL98130B1 (pl) 1978-04-29
HU172465B (hu) 1978-09-28
PL98958B1 (pl) 1978-06-30
ZA742445B (en) 1975-05-28
CS180011B2 (en) 1977-12-30
CS180048B2 (en) 1977-12-30
FI149274A (es) 1974-11-19
AR208350A1 (es) 1976-12-20
US3881017A (en) 1975-04-29
AR207448A1 (es) 1976-10-08
IE39573B1 (en) 1978-11-08
AR209769A1 (es) 1977-05-31

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