MA54695A - Inhibiteurs de dihydroorotate déshydrogénase - Google Patents
Inhibiteurs de dihydroorotate déshydrogénaseInfo
- Publication number
- MA54695A MA54695A MA054695A MA54695A MA54695A MA 54695 A MA54695 A MA 54695A MA 054695 A MA054695 A MA 054695A MA 54695 A MA54695 A MA 54695A MA 54695 A MA54695 A MA 54695A
- Authority
- MA
- Morocco
- Prior art keywords
- dehydrogenase inhibitors
- dihydroorotate dehydrogenase
- dihydroorotate
- inhibitors
- dehydrogenase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962791057P | 2019-01-11 | 2019-01-11 | |
| US201962859851P | 2019-06-11 | 2019-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA54695A true MA54695A (fr) | 2021-11-17 |
Family
ID=69326572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA054695A MA54695A (fr) | 2019-01-11 | 2020-01-10 | Inhibiteurs de dihydroorotate déshydrogénase |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20220089568A1 (fr) |
| EP (1) | EP3908579B1 (fr) |
| JP (1) | JP2022517086A (fr) |
| KR (1) | KR20210114968A (fr) |
| CN (1) | CN113574054A (fr) |
| AU (1) | AU2020205842A1 (fr) |
| BR (1) | BR112021013134A2 (fr) |
| CA (1) | CA3126330A1 (fr) |
| IL (1) | IL284537A (fr) |
| MA (1) | MA54695A (fr) |
| MX (1) | MX2021008400A (fr) |
| SG (1) | SG11202107276WA (fr) |
| TW (1) | TW202043208A (fr) |
| WO (1) | WO2020144638A1 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202104207A (zh) | 2019-04-17 | 2021-02-01 | 美商健生生物科技公司 | 二氫乳清酸脫氫酶抑制劑 |
| JP2023535346A (ja) * | 2020-07-14 | 2023-08-17 | ナンジン ゼンシャイン ファーマシューティカルズ カンパニー リミテッド | Ｄｈｏｄｈ阻害剤としての化合物 |
| CN116249702A (zh) * | 2020-09-28 | 2023-06-09 | 微境生物医药科技(上海)有限公司 | 用作dhodh抑制剂的1,2,4-三唑酮衍生物 |
| WO2022070069A1 (fr) * | 2020-09-30 | 2022-04-07 | Janssen Biotech, Inc. | Inhibiteurs de la dihydroorotate déshydrogénase |
| WO2022074534A1 (fr) | 2020-10-05 | 2022-04-14 | Janssen Biotech, Inc. | Combinaisons d'inhibiteurs de dihydroorotate déshydrogénase et d'agents hypométhylants |
| EP4313150A1 (fr) | 2021-03-26 | 2024-02-07 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Combinaison d'inhibiteur de la biosynthèse de la pyrimidine destinée à être utilisée dans le traitement d'infections virales |
| WO2023280181A1 (fr) * | 2021-07-05 | 2023-01-12 | 微境生物医药科技(上海)有限公司 | Dérivé de 1,2,4-triazolone utile en tant qu'inhibiteur de dhodh, son procédé de préparation et son utilisation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20190094A1 (ar) * | 2016-10-27 | 2019-04-25 | Broad Inst Inc | مركبات 1، 2، 4-تريازولون تحمل ثلاثة بدائل عند المواقع 2، 4، 5 مفيدة كمثبطات لديهيدروجيناز ثنائي هيدرو أوروتات (dhodh) |
-
2020
- 2020-01-09 TW TW109100712A patent/TW202043208A/zh unknown
- 2020-01-10 WO PCT/IB2020/050180 patent/WO2020144638A1/fr unknown
- 2020-01-10 CA CA3126330A patent/CA3126330A1/fr active Pending
- 2020-01-10 MA MA054695A patent/MA54695A/fr unknown
- 2020-01-10 SG SG11202107276WA patent/SG11202107276WA/en unknown
- 2020-01-10 BR BR112021013134-5A patent/BR112021013134A2/pt not_active Application Discontinuation
- 2020-01-10 JP JP2021540230A patent/JP2022517086A/ja active Pending
- 2020-01-10 MX MX2021008400A patent/MX2021008400A/es unknown
- 2020-01-10 CN CN202080020407.4A patent/CN113574054A/zh active Pending
- 2020-01-10 AU AU2020205842A patent/AU2020205842A1/en not_active Abandoned
- 2020-01-10 EP EP20702357.3A patent/EP3908579B1/fr active Active
- 2020-01-10 US US17/421,741 patent/US20220089568A1/en active Pending
- 2020-01-10 KR KR1020217025217A patent/KR20210114968A/ko unknown
-
2021
- 2021-07-01 IL IL284537A patent/IL284537A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020144638A1 (fr) | 2020-07-16 |
| MX2021008400A (es) | 2021-08-16 |
| SG11202107276WA (en) | 2021-07-29 |
| IL284537A (en) | 2021-08-31 |
| BR112021013134A2 (pt) | 2021-09-28 |
| TW202043208A (zh) | 2020-12-01 |
| JP2022517086A (ja) | 2022-03-04 |
| US20220089568A1 (en) | 2022-03-24 |
| KR20210114968A (ko) | 2021-09-24 |
| EP3908579B1 (fr) | 2023-12-27 |
| CA3126330A1 (fr) | 2020-07-16 |
| AU2020205842A1 (en) | 2021-07-22 |
| EP3908579A1 (fr) | 2021-11-17 |
| CN113574054A (zh) | 2021-10-29 |
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