MA51305A - Stimulateurs de sgc - Google Patents

Stimulateurs de sgc

Info

Publication number
MA51305A
MA51305A MA051305A MA51305A MA51305A MA 51305 A MA51305 A MA 51305A MA 051305 A MA051305 A MA 051305A MA 51305 A MA51305 A MA 51305A MA 51305 A MA51305 A MA 51305A
Authority
MA
Morocco
Prior art keywords
stimulators
cms
cms stimulators
Prior art date
Application number
MA051305A
Other languages
English (en)
Inventor
Helen Cumberbatch
Ara Mermerian
Takashi Nakai
Paul Allan Renhowe
Glen Robert Rennie
Original Assignee
Cyclerion Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyclerion Therapeutics Inc filed Critical Cyclerion Therapeutics Inc
Publication of MA51305A publication Critical patent/MA51305A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MA051305A 2017-12-19 2018-12-19 Stimulateurs de sgc MA51305A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762607619P 2017-12-19 2017-12-19

Publications (1)

Publication Number Publication Date
MA51305A true MA51305A (fr) 2020-10-28

Family

ID=65024070

Family Applications (1)

Application Number Title Priority Date Filing Date
MA051305A MA51305A (fr) 2017-12-19 2018-12-19 Stimulateurs de sgc

Country Status (15)

Country Link
US (1) US11897887B2 (fr)
EP (1) EP3727388A1 (fr)
JP (1) JP7337067B2 (fr)
KR (1) KR20200100696A (fr)
CN (1) CN111712247B (fr)
AU (1) AU2018388629B2 (fr)
BR (1) BR112020012629A2 (fr)
CA (1) CA3086207A1 (fr)
EA (1) EA202091502A1 (fr)
IL (1) IL275415A (fr)
MA (1) MA51305A (fr)
MX (1) MX2020006433A (fr)
PH (1) PH12020550956A1 (fr)
SG (1) SG11202005718PA (fr)
WO (1) WO2019126354A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018009597A1 (fr) * 2016-07-07 2018-01-11 Ironwood Pharmaceuticals, Inc. Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble
SG11202100092QA (en) 2018-07-11 2021-02-25 Cyclerion Therapeutics Inc USE OF sGC STIMULATORS FOR THE TREATMENT OF MITOCHONRIAL DISORDERS
WO2022225902A1 (fr) 2021-04-20 2022-10-27 Cyclerion Therapeutics, Inc. Traitement de maladies du snc avec des stimulateurs de sgc
CA3216127A1 (fr) 2021-04-20 2022-10-27 Lei Jia Stimulateurs de sgc
WO2023148203A1 (fr) 2022-02-01 2023-08-10 Charité - Universitätsmedizin Berlin Activateur de guanylate cyclase soluble pour le traitement d'un dysfonctionnement vasculaire chronique
WO2024086179A1 (fr) * 2022-10-18 2024-04-25 Tisento Therapeutics, Inc. Stimulateurs de la sgc pyrimidiques
WO2024086182A1 (fr) 2022-10-18 2024-04-25 Tisento Therapeutics Inc. Traitement de maladies mitochondriales avec stimulateurs de sgc

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2928079B2 (ja) 1994-02-14 1999-07-28 永信薬品工業股▲ふん▼有限公司 １−（置換ベンジル）−３−（置換アリール）縮合ピラゾール類、その製造法及びその用途
DE19744026A1 (de) 1997-10-06 1999-04-08 Hoechst Marion Roussel De Gmbh Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln
DK1095016T3 (da) 1998-07-08 2006-03-13 Sanofi Aventis Deutschland Svovlsubstituerede sulfonylaminocarboxylsyre-N-arylamider, deres fremstilling, deres anvendelse og farmaceutiske præparater omfattende dem
DE19830430A1 (de) 1998-07-08 2000-01-13 Hoechst Marion Roussel De Gmbh Schwefelsubstituierte Sulfonylamino-carbonsäure-N-arylamide, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19834044A1 (de) 1998-07-29 2000-02-03 Bayer Ag Neue substituierte Pyrazolderivate
DE19834047A1 (de) 1998-07-29 2000-02-03 Bayer Ag Substituierte Pyrazolderivate
GB9824310D0 (en) 1998-11-05 1998-12-30 Univ London Activators of soluble guanylate cyclase
DE19942809A1 (de) 1999-09-08 2001-03-15 Bayer Ag Verfahren zur Herstellung substituierter Pyrimidinderivate
DE19943635A1 (de) 1999-09-13 2001-03-15 Bayer Ag Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
AUPR237301A0 (en) * 2001-01-02 2001-01-25 Fujisawa Pharmaceutical Co., Ltd. Benzhydryl derivatives
DE10216145A1 (de) 2002-04-12 2003-10-23 Bayer Ag Verwendung von Stimulatoren der löslichen Guanylatcyclase zur Behandlung von Glaukom
DE10220570A1 (de) * 2002-05-08 2003-11-20 Bayer Ag Carbamat-substituierte Pyrazolopyridine
US7709468B2 (en) * 2005-09-02 2010-05-04 Abbott Laboratories Imidazo based heterocycles
EP2197551B1 (fr) 2007-09-06 2016-12-28 Merck Sharp & Dohme Corp. Activateurs de la guanylate cyclase soluble
EP2244575B1 (fr) 2008-01-24 2013-07-17 Merck Sharp & Dohme Corp. Antagonistes du récepteur de l'angiotensine ii
US8741910B2 (en) 2008-11-25 2014-06-03 Merck Sharp & Dohme Corp. Soluble guanylate cyclase activators
JP5411300B2 (ja) 2009-02-26 2014-02-12 メルク・シャープ・アンド・ドーム・コーポレーション 可溶性グアニレートシクラーゼ活性化剤
US9284301B2 (en) 2010-03-25 2016-03-15 Merck Sharp & Dohme Corp. Soluble guanylate cyclase activators
DE102010021637A1 (de) * 2010-05-26 2011-12-01 Bayer Schering Pharma Aktiengesellschaft Substituierte 5-Fluor-1H-Pyrazolopyridine und ihre Verwendung
ES2564503T3 (es) 2010-05-27 2016-03-23 Merck Sharp & Dohme Corp. Activadores de la guanilato-ciclasa soluble
WO2012058132A1 (fr) 2010-10-28 2012-05-03 Merck Sharp & Dohme Corp. Activateurs de la guanylate cyclase soluble
DE102011075399A1 (de) * 2011-05-06 2012-11-08 Bayer Pharma Aktiengesellschaft Substituierte Imidazopyridine und Imidazopyridazine und ihre Verwendung
DE102012200356A1 (de) 2012-01-11 2013-07-11 Bayer Intellectual Property Gmbh Substituierte Imidazopyridine und Imidazopyridazine und ihre Verwendung
DE102011007890A1 (de) 2011-04-21 2012-10-25 Bayer Pharma Aktiengesellschaft Fluoralkyl-substituierte Pyrazolopyridine und ihre Verwendung
CN110016020B (zh) 2013-03-15 2022-07-26 赛克里翁治疗有限公司 化合物或其药学上可接受的盐及其应用和药物组合物
US20160311826A1 (en) * 2013-12-11 2016-10-27 Ironwood Pharmaceuticals, Inc. Sgc stimulators
WO2015106268A1 (fr) * 2014-01-13 2015-07-16 Ironwood Pharmaceuticals, Inc. Utilisation de stimulateurs de la sgc pour le traitement de troubles neuromusculaires
WO2015187470A1 (fr) * 2014-06-04 2015-12-10 Merck Sharp & Dohme Corp. Dérivés d'imidazo-pyrazine utiles en tant qu'activateurs de guanylate cyclases solubles
WO2016044447A1 (fr) * 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. Dérivés de pyrazole utilisés comme stimulateurs de sgc
TW201625635A (zh) 2014-11-21 2016-07-16 默沙東藥廠 作為可溶性鳥苷酸環化酶活化劑之三唑并吡基衍生物
US10213429B2 (en) * 2015-05-28 2019-02-26 Merck Sharp & Dohme Corp. Imidazo-pyrazinyl derivatives useful as soluble guanylate cyclase activators
WO2017197555A1 (fr) * 2016-05-16 2017-11-23 Merck Sharp & Dohme Corp. Dérivés de pyrazine fusionnés utiles en tant que stimulateurs de la guanylate cyclase soluble

Also Published As

Publication number Publication date
JP7337067B2 (ja) 2023-09-01
PH12020550956A1 (en) 2021-03-22
AU2018388629B2 (en) 2023-11-16
CN111712247A (zh) 2020-09-25
EA202091502A1 (ru) 2020-11-12
AU2018388629A1 (en) 2020-07-30
IL275415A (en) 2020-07-30
CA3086207A1 (fr) 2019-06-27
JP2021508326A (ja) 2021-03-04
US11897887B2 (en) 2024-02-13
US20200377508A1 (en) 2020-12-03
CN111712247B (zh) 2024-02-09
MX2020006433A (es) 2020-09-17
EP3727388A1 (fr) 2020-10-28
BR112020012629A2 (pt) 2020-12-01
SG11202005718PA (en) 2020-07-29
KR20200100696A (ko) 2020-08-26
WO2019126354A1 (fr) 2019-06-27

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