MA50630A - Procédé de préparation de dérivés d'alpha-carboxamide de pyrrolidine - Google Patents
Procédé de préparation de dérivés d'alpha-carboxamide de pyrrolidineInfo
- Publication number
- MA50630A MA50630A MA050630A MA50630A MA50630A MA 50630 A MA50630 A MA 50630A MA 050630 A MA050630 A MA 050630A MA 50630 A MA50630 A MA 50630A MA 50630 A MA50630 A MA 50630A
- Authority
- MA
- Morocco
- Prior art keywords
- pyrrolidine
- alpha
- preparation
- carboxamide derivatives
- carboxamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762568651P | 2017-10-05 | 2017-10-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA50630A true MA50630A (fr) | 2021-03-31 |
Family
ID=65995302
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA050630A MA50630A (fr) | 2017-10-05 | 2018-10-05 | Procédé de préparation de dérivés d'alpha-carboxamide de pyrrolidine |
Country Status (12)
Country | Link |
---|---|
US (2) | US11192856B2 (fr) |
EP (1) | EP3691634A4 (fr) |
JP (1) | JP2020536870A (fr) |
KR (1) | KR20200061381A (fr) |
CN (1) | CN112153968A (fr) |
AU (2) | AU2018346763A1 (fr) |
CA (1) | CA3076823A1 (fr) |
IL (1) | IL273639B2 (fr) |
MA (1) | MA50630A (fr) |
MX (1) | MX2020003811A (fr) |
SG (2) | SG11202002706XA (fr) |
WO (1) | WO2019071162A2 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11192856B2 (en) | 2017-10-05 | 2021-12-07 | Biogen Inc. | Process for preparing alpha-carboxamide pyrrolidine derivatives |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3164597A (en) | 1962-12-17 | 1965-01-05 | Geigy Chem Corp | 5-carboxylic acid-2-phenyl-pyrrolines, corresponding pyrrolidines and functional derivatives thereof |
CH674205A5 (fr) * | 1988-05-11 | 1990-05-15 | Lonza Ag | |
IL94466A (en) | 1989-05-25 | 1995-01-24 | Erba Carlo Spa | Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation |
US6201016B1 (en) | 1994-06-27 | 2001-03-13 | Cytomed Incorporated | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders |
GB9618349D0 (en) | 1996-09-03 | 1996-10-16 | Pharmacia Spa | N-substituted 2-amino-4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibitory activity |
IT1290910B1 (it) | 1997-02-03 | 1998-12-14 | Sigma Tau Ind Farmaceuti | 2-amminotetralina otticamente attiva, procedimento per la sua preparazione e composizioni farmaceutiche che la contengono, attive |
GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
EP2266960B1 (fr) | 1999-03-26 | 2014-01-22 | Euro-Celtique S.A. | Pyrazoles, imidazoles, oxazoles, thiazoles et pyrroles, substitués d'aryl à titre d'anticonvulsants |
GB9923748D0 (en) | 1999-10-07 | 1999-12-08 | Glaxo Group Ltd | Chemical compounds |
IT1317049B1 (it) | 2000-06-23 | 2003-05-26 | Sigma Tau Ind Farmaceuti | Composti utili per la preparazione di medicamenti ad attivita'inibitrice della fosfodiesterasi iv. |
GB0115517D0 (en) | 2001-06-25 | 2001-08-15 | Ferring Bv | Novel antidiabetic agents |
PA8583001A1 (es) | 2002-09-20 | 2004-04-23 | Hoffmann La Roche | Derivados de 4-pirrolidino-fenil-bencil eter como inhibidores de mao-b |
MY142651A (en) | 2003-03-18 | 2010-12-15 | Merck Sharp & Dohme | Biaryl substituted triazoles as sodium channel blockers |
AU2004230854A1 (en) | 2003-04-03 | 2004-10-28 | Merck & Co., Inc. | Biaryl substituted pyrazoles as sodium channel blockers |
CN1805945A (zh) | 2003-04-18 | 2006-07-19 | 麦克公司 | 作为钠通道阻滞剂的联芳基取代的噻唑、噁唑和咪唑 |
WO2005000309A2 (fr) | 2003-06-27 | 2005-01-06 | Ionix Pharmaceuticals Limited | Composes chimiques |
EP1524265A1 (fr) | 2003-10-15 | 2005-04-20 | Newron Pharmaceuticals S.p.A. | Dérivés de prolinamide en tant que bloqueurs du canal sodium et/ou calcium ou inhibiteurs sélectifs de MAO-B |
US7253168B2 (en) | 2004-04-07 | 2007-08-07 | Neurogen Corporation | Substituted 1-benzyl-4-substituted piperazine analogues |
WO2005100334A1 (fr) | 2004-04-14 | 2005-10-27 | Pfizer Products Inc. | Inhibiteurs de dipeptidyl peptidase-iv |
JP2008540443A (ja) | 2005-05-04 | 2008-11-20 | バーテックス ファーマシューティカルズ インコーポレイテッド | イオンチャネルのモジュレーターとして有用なピリミジンおよびピラジン |
WO2006119390A1 (fr) | 2005-05-04 | 2006-11-09 | Vertex Pharmaceuticals Incorporated | Pyridines utiles en tant que modulateurs de canaux ioniques |
EP1888549A2 (fr) | 2005-05-19 | 2008-02-20 | Vertex Pharmaceuticals, Inc. | Biaryles utiles en tant que modulateurs des canaux ioniques |
AR058805A1 (es) | 2005-09-09 | 2008-02-27 | Smithkline Beecham Corp | Derivados biciclicos de piridina utiles como agentes antipsicoticos |
US7855218B2 (en) | 2005-10-10 | 2010-12-21 | Convergence Pharmaceuticals Limited | Compounds |
TW200730494A (en) * | 2005-10-10 | 2007-08-16 | Glaxo Group Ltd | Novel compounds |
TW200728258A (en) | 2005-10-10 | 2007-08-01 | Glaxo Group Ltd | Novel compounds |
TW200808788A (en) * | 2006-04-19 | 2008-02-16 | Astellas Pharma Inc | Azolecarboxamide derivative |
JP2007290973A (ja) * | 2006-04-21 | 2007-11-08 | Univ Nagoya | 亜鉛−マグネシウムアート錯体を含む求核試薬及びそれを使用する求核付加体の製造方法 |
GB0701365D0 (en) | 2007-01-24 | 2007-03-07 | Glaxo Group Ltd | Novel pharmaceutical compositions |
GB0701366D0 (en) | 2007-01-24 | 2007-03-07 | Glaxo Group Ltd | Novel pharmaceutical compositions |
US20100105688A1 (en) | 2007-01-24 | 2010-04-29 | Glaxo Group Limited | Pharmaceutical compositions comprising 3,5-diamino-6-(2,3-dichlophenyl)-1,2,4-triazine or r(-)-2,4-diamino-5-(2,3-dichlorophenyl)-6-fluoromethyl pyrimidine and an nk1 |
GB0706630D0 (en) | 2007-04-04 | 2007-05-16 | Glaxo Group Ltd | Novel compounds |
DK2477964T5 (en) | 2009-09-14 | 2015-05-26 | Convergence Pharmaceuticals | A process for the preparation of alpha-carboxamide |
US20110144081A1 (en) * | 2009-12-15 | 2011-06-16 | Henner Knust | Pyrrolidine derivatives |
WO2011155337A1 (fr) | 2010-06-11 | 2011-12-15 | シャープ株式会社 | Dispositif à cristaux liquides |
SI2598479T1 (sl) * | 2010-11-11 | 2015-06-30 | Aarti Healthcare Limited | Postopek za pripravo ramiprila |
WO2016102967A1 (fr) * | 2014-12-23 | 2016-06-30 | Convergence Pharmaceuticals Limited | Procédé de préparation de dérivés d'alpha-carboxamide de pyrrolidine |
WO2016160574A2 (fr) | 2015-03-27 | 2016-10-06 | Scifluor Life Sciences, Inc. | Composés d'aryl-et hétéroaryl-pyrrolidine-2-carboxamide |
CN106467513A (zh) * | 2016-09-30 | 2017-03-01 | 陕西科技大学 | 一种制备Niraparib的合成方法 |
US11192856B2 (en) | 2017-10-05 | 2021-12-07 | Biogen Inc. | Process for preparing alpha-carboxamide pyrrolidine derivatives |
MX2021012420A (es) | 2019-04-10 | 2022-02-10 | Biogen Ma Inc | Proceso para preparar derivados de pirrolidina alfa-carboxamida. |
EA202192764A1 (ru) | 2019-04-10 | 2022-03-10 | Байоджен Инк. | Способы получения производных альфа-карбоксамид пирролидина |
-
2018
- 2018-10-05 US US16/753,680 patent/US11192856B2/en active Active
- 2018-10-05 SG SG11202002706XA patent/SG11202002706XA/en unknown
- 2018-10-05 AU AU2018346763A patent/AU2018346763A1/en not_active Abandoned
- 2018-10-05 MX MX2020003811A patent/MX2020003811A/es unknown
- 2018-10-05 JP JP2020519296A patent/JP2020536870A/ja not_active Withdrawn
- 2018-10-05 CN CN201880078496.0A patent/CN112153968A/zh not_active Withdrawn
- 2018-10-05 EP EP18864468.6A patent/EP3691634A4/fr not_active Withdrawn
- 2018-10-05 CA CA3076823A patent/CA3076823A1/fr not_active Withdrawn
- 2018-10-05 SG SG10202112966SA patent/SG10202112966SA/en unknown
- 2018-10-05 MA MA050630A patent/MA50630A/fr unknown
- 2018-10-05 WO PCT/US2018/054661 patent/WO2019071162A2/fr active Application Filing
- 2018-10-05 KR KR1020207011959A patent/KR20200061381A/ko unknown
-
2020
- 2020-03-26 IL IL273639A patent/IL273639B2/en unknown
-
2021
- 2021-11-24 US US17/534,679 patent/US20220356154A1/en not_active Abandoned
-
2023
- 2023-06-26 AU AU2023204011A patent/AU2023204011A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
MX2020003811A (es) | 2021-01-15 |
IL273639B1 (en) | 2023-03-01 |
CA3076823A1 (fr) | 2019-04-11 |
KR20200061381A (ko) | 2020-06-02 |
WO2019071162A2 (fr) | 2019-04-11 |
SG11202002706XA (en) | 2020-04-29 |
IL273639B2 (en) | 2023-07-01 |
SG10202112966SA (en) | 2021-12-30 |
WO2019071162A3 (fr) | 2020-03-26 |
US20200270206A1 (en) | 2020-08-27 |
EP3691634A4 (fr) | 2021-03-31 |
IL273639A (en) | 2020-05-31 |
EP3691634A2 (fr) | 2020-08-12 |
AU2018346763A1 (en) | 2020-04-16 |
JP2020536870A (ja) | 2020-12-17 |
AU2023204011A1 (en) | 2023-07-13 |
US20220356154A1 (en) | 2022-11-10 |
US11192856B2 (en) | 2021-12-07 |
CN112153968A (zh) | 2020-12-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA49752A (fr) | Procédés de préparation de composés de pyrrolidine | |
MA52665A (fr) | Procédé d'amélioration de l'expression de l'hémoglobine foetale | |
MA51988A (fr) | Procédé pour la préparation de composés utiles à traiter l'amyotrophie spinale | |
MA43746A (fr) | Dérivés de 2-cyanoisoindoline pour le traitement du cancer | |
MA49700A (fr) | Procédé amélioré pour la préparation de dérivés d'aminopyrimidine | |
MA45155A (fr) | Procédés de préparation d'oligomères morpholino de phosphorodiamidate | |
MA49472A (fr) | Procédé de préparation d'intermédiaire de dérivé de 4-méthoxypyrrole | |
MA52906A (fr) | Procédé de préparation d'amg 416 | |
MA51629A (fr) | Procédés de production, purification et formulation de conjugués anticorps-médicaments | |
MA45183A (fr) | Procédés de préparation d'oligomères morpholino de phosphorodiamidate | |
MA49775A (fr) | Procédés de préparation d'oligomères morpholino de phosphorodiamidate | |
MA50169A (fr) | Procédé de production d'un électrocatalyseur | |
MA48626A (fr) | Procédé de préparation de (3r,4s)-3-acétamido-4-allyl-n-(tert-butyl)pyrrolidine-3-carboxamide | |
MA55917A (fr) | Procédé de cristallisation de dérivés d'aripiprazole dans des formulations à libération prolongée pour le traitement de la schizophrénie | |
MA51133A (fr) | Dérivés de pyrrole utilisés en tant qu'inhibiteurs d'acc | |
MA42423A (fr) | Procédé de préparation d'un revêtement | |
MA45768A (fr) | Procédé pour la préparation de compositions d'immunoglobulines | |
MA54396A (fr) | Procédé de préparation de n-phénylpyrazole-1-carboxamides | |
MA53370A (fr) | Procédé et intermédiaires pour la préparation de bilastine | |
MA50517A (fr) | Procédé de préparation d'intermédiaire de dérivé de 4-méthoxypyrrole | |
IL276483A (en) | A continuous process for the preparation of trazodone | |
MA47022A (fr) | Procédé efficace de préparation de conjugués agent de liaison cellulaire-agent cytotoxique | |
MA51870A (fr) | Procédé pour la préparation de composés coupleurs de médicaments | |
CY1122172T1 (el) | Τροποποιητες θειαζολης των a3 υποδοχεων αδενοσινης | |
PT3830073T (pt) | Processo de preparação monotópica de compostos organoiodados intermediários para síntese de ioversol |