SG10202112966SA - Process for preparing αlpha-carboxamide pyrrolidine derivatives - Google Patents
Process for preparing αlpha-carboxamide pyrrolidine derivativesInfo
- Publication number
- SG10202112966SA SG10202112966SA SG10202112966SA SG10202112966SA SG10202112966SA SG 10202112966S A SG10202112966S A SG 10202112966SA SG 10202112966S A SG10202112966S A SG 10202112966SA SG 10202112966S A SG10202112966S A SG 10202112966SA SG 10202112966S A SG10202112966S A SG 10202112966SA
- Authority
- SG
- Singapore
- Prior art keywords
- αlpha
- preparing
- pyrrolidine derivatives
- carboxamide pyrrolidine
- carboxamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762568651P | 2017-10-05 | 2017-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202112966SA true SG10202112966SA (en) | 2021-12-30 |
Family
ID=65995302
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202002706XA SG11202002706XA (en) | 2017-10-05 | 2018-10-05 | Process for preparing alpha-carboxamide pyrolidine derivatives |
| SG10202112966SA SG10202112966SA (en) | 2017-10-05 | 2018-10-05 | Process for preparing αlpha-carboxamide pyrrolidine derivatives |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202002706XA SG11202002706XA (en) | 2017-10-05 | 2018-10-05 | Process for preparing alpha-carboxamide pyrolidine derivatives |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11192856B2 (en) |
| EP (1) | EP3691634A4 (en) |
| JP (1) | JP2020536870A (en) |
| KR (1) | KR20200061381A (en) |
| CN (1) | CN112153968A (en) |
| AU (2) | AU2018346763A1 (en) |
| CA (1) | CA3076823A1 (en) |
| IL (1) | IL273639B2 (en) |
| MA (1) | MA50630A (en) |
| MX (1) | MX2020003811A (en) |
| SG (2) | SG11202002706XA (en) |
| WO (1) | WO2019071162A2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018346763A1 (en) | 2017-10-05 | 2020-04-16 | Biogen Inc. | Process for preparing alpha-carboxamide pyrolidine derivatives |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3164597A (en) | 1962-12-17 | 1965-01-05 | Geigy Chem Corp | 5-carboxylic acid-2-phenyl-pyrrolines, corresponding pyrrolidines and functional derivatives thereof |
| CH674205A5 (en) * | 1988-05-11 | 1990-05-15 | Lonza Ag | |
| IL94466A (en) | 1989-05-25 | 1995-01-24 | Erba Carlo Spa | Pharmaceutical compositions containing n-phenylalkyl substituted alpha-amino carboxamide derivatives, some such novel compounds and their preparation |
| US6201016B1 (en) | 1994-06-27 | 2001-03-13 | Cytomed Incorporated | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders |
| GB9618349D0 (en) | 1996-09-03 | 1996-10-16 | Pharmacia Spa | N-substituted 2-amino-4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibitory activity |
| IT1290910B1 (en) | 1997-02-03 | 1998-12-14 | Sigma Tau Ind Farmaceuti | 2-OPTICALLY ACTIVE AMINOTETRALINE, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT, ACTIVE |
| GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| US6414011B1 (en) | 1999-03-26 | 2002-07-02 | Euro-Celtique S.A. | Aryl substituted pyrazoles, and pyrroles, and the use thereof |
| GB9923748D0 (en) | 1999-10-07 | 1999-12-08 | Glaxo Group Ltd | Chemical compounds |
| IT1317049B1 (en) | 2000-06-23 | 2003-05-26 | Sigma Tau Ind Farmaceuti | USEFUL COMPOUNDS FOR THE PREPARATION OF MEDICATIONS FOR PHOSPHODIESTERASE INHIBITING ACTIVITIES IV. |
| GB0115517D0 (en) | 2001-06-25 | 2001-08-15 | Ferring Bv | Novel antidiabetic agents |
| MY134480A (en) | 2002-09-20 | 2007-12-31 | Hoffmann La Roche | 4-pyrrolidino-phenyl-benzyl ether derivatives |
| MY142651A (en) | 2003-03-18 | 2010-12-15 | Merck Sharp & Dohme | Biaryl substituted triazoles as sodium channel blockers |
| CN101333192A (en) | 2003-04-03 | 2008-12-31 | 默克公司 | Biaryl substituted pyrazoles as sodium channel blockers |
| US20070060584A1 (en) | 2003-04-18 | 2007-03-15 | Chakravarty Prasun K | Biaryl substituted thiazoles, oxazoles and imidazoles as sodium channel blockers |
| WO2005000309A2 (en) | 2003-06-27 | 2005-01-06 | Ionix Pharmaceuticals Limited | Chemical compounds |
| EP1524265A1 (en) | 2003-10-15 | 2005-04-20 | Newron Pharmaceuticals S.p.A. | Prolinamide derivatives as sodium and/or calcium channel blockers or selective MAO-B inhibitors |
| WO2005110982A2 (en) | 2004-04-07 | 2005-11-24 | Neurogen Corporation | Substituted 1-benzyl-4-substituted piperazine analogues |
| WO2005100334A1 (en) | 2004-04-14 | 2005-10-27 | Pfizer Products Inc. | Dipeptidyl peptidase-iv inhibitors |
| JP2008540438A (en) | 2005-05-04 | 2008-11-20 | バーテックス ファーマシューティカルズ インコーポレイテッド | Pyridines useful as ion channel modulators |
| JP2008540443A (en) | 2005-05-04 | 2008-11-20 | バーテックス ファーマシューティカルズ インコーポレイテッド | Pyrimidines and pyrazines useful as modulators of ion channels |
| EP1888549A2 (en) | 2005-05-19 | 2008-02-20 | Vertex Pharmaceuticals, Inc. | Biaryls useful as modulators of ion channels |
| AU2006289281B2 (en) | 2005-09-09 | 2012-05-17 | KaNDy Therapeutics Ltd. | Pyridine derivatives and their use in the treatment of psychotic disorders |
| TW200728258A (en) | 2005-10-10 | 2007-08-01 | Glaxo Group Ltd | Novel compounds |
| JP5139307B2 (en) | 2005-10-10 | 2013-02-06 | グラクソ グループ リミテッド | Prolinamide derivatives as sodium channel modulators |
| TW200730494A (en) | 2005-10-10 | 2007-08-16 | Glaxo Group Ltd | Novel compounds |
| EP2009005A4 (en) * | 2006-04-19 | 2010-06-02 | Astellas Pharma Inc | Azolecarboxamide derivative |
| JP2007290973A (en) * | 2006-04-21 | 2007-11-08 | Univ Nagoya | Nucleophilic reagent containing zinc-magnesium ate complex and method for producing nucleophilic adduct using the same |
| GB0701365D0 (en) | 2007-01-24 | 2007-03-07 | Glaxo Group Ltd | Novel pharmaceutical compositions |
| KR20090112722A (en) | 2007-01-24 | 2009-10-28 | 글락소 그룹 리미티드 | Pharmaceutical compositions comprising 3,5-diamino-6-2,3-dichl0rophenyl-1,2,4-triazine or r--2,4-diamino-5-2,3-dichlorophenyl-6-fluoromethyl pyrimidine and an nk1 |
| GB0701366D0 (en) | 2007-01-24 | 2007-03-07 | Glaxo Group Ltd | Novel pharmaceutical compositions |
| GB0706630D0 (en) | 2007-04-04 | 2007-05-16 | Glaxo Group Ltd | Novel compounds |
| US8759542B2 (en) | 2009-09-14 | 2014-06-24 | Convergence Pharmaceuticals Limited | Process for preparing alpha-carboxamide derivatives |
| US20110144081A1 (en) * | 2009-12-15 | 2011-06-16 | Henner Knust | Pyrrolidine derivatives |
| WO2011155337A1 (en) | 2010-06-11 | 2011-12-15 | シャープ株式会社 | Liquid crystal device |
| CN103282350B (en) * | 2010-11-11 | 2015-02-04 | 阿尔蒂医疗有限公司 | A method for preparing ramipril |
| ES2912881T3 (en) * | 2014-12-23 | 2022-05-30 | Convergence Pharmaceuticals | Procedure for preparing alpha-carboxamide pyrrolidine derivatives |
| WO2016160574A2 (en) | 2015-03-27 | 2016-10-06 | Scifluor Life Sciences, Inc. | Aryl- and heteroaryl-pyrrolidine-2-carboxamide compounds |
| CN106467513A (en) * | 2016-09-30 | 2017-03-01 | 陕西科技大学 | A kind of synthetic method preparing Niraparib |
| AU2018346763A1 (en) | 2017-10-05 | 2020-04-16 | Biogen Inc. | Process for preparing alpha-carboxamide pyrolidine derivatives |
| EP3953329A4 (en) | 2019-04-10 | 2022-12-21 | Biogen MA Inc. | Process for preparing alpha-carboxamide pyrrolidine derivatives |
| EA202192764A1 (en) | 2019-04-10 | 2022-03-10 | Байоджен Инк. | METHODS FOR OBTAINING ALPHA-CARBOXAMIDE PYRROLIDINE DERIVATIVES |
-
2018
- 2018-10-05 AU AU2018346763A patent/AU2018346763A1/en not_active Abandoned
- 2018-10-05 CA CA3076823A patent/CA3076823A1/en not_active Withdrawn
- 2018-10-05 US US16/753,680 patent/US11192856B2/en active Active
- 2018-10-05 CN CN201880078496.0A patent/CN112153968A/en not_active Withdrawn
- 2018-10-05 WO PCT/US2018/054661 patent/WO2019071162A2/en active Application Filing
- 2018-10-05 JP JP2020519296A patent/JP2020536870A/en not_active Withdrawn
- 2018-10-05 MA MA050630A patent/MA50630A/en unknown
- 2018-10-05 MX MX2020003811A patent/MX2020003811A/en unknown
- 2018-10-05 SG SG11202002706XA patent/SG11202002706XA/en unknown
- 2018-10-05 EP EP18864468.6A patent/EP3691634A4/en not_active Withdrawn
- 2018-10-05 SG SG10202112966SA patent/SG10202112966SA/en unknown
- 2018-10-05 KR KR1020207011959A patent/KR20200061381A/en unknown
-
2020
- 2020-03-26 IL IL273639A patent/IL273639B2/en unknown
-
2021
- 2021-11-24 US US17/534,679 patent/US20220356154A1/en not_active Abandoned
-
2023
- 2023-06-26 AU AU2023204011A patent/AU2023204011A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| MX2020003811A (en) | 2021-01-15 |
| WO2019071162A3 (en) | 2020-03-26 |
| US20220356154A1 (en) | 2022-11-10 |
| SG11202002706XA (en) | 2020-04-29 |
| AU2023204011A1 (en) | 2023-07-13 |
| EP3691634A4 (en) | 2021-03-31 |
| AU2018346763A1 (en) | 2020-04-16 |
| US20200270206A1 (en) | 2020-08-27 |
| IL273639B1 (en) | 2023-03-01 |
| CA3076823A1 (en) | 2019-04-11 |
| MA50630A (en) | 2021-03-31 |
| CN112153968A (en) | 2020-12-29 |
| KR20200061381A (en) | 2020-06-02 |
| EP3691634A2 (en) | 2020-08-12 |
| IL273639B2 (en) | 2023-07-01 |
| US11192856B2 (en) | 2021-12-07 |
| JP2020536870A (en) | 2020-12-17 |
| WO2019071162A2 (en) | 2019-04-11 |
| IL273639A (en) | 2020-05-31 |
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