MA48751A - Paradigme de traitement pour un traitement combiné d'anticorps anti-cd19 et de venetoclax - Google Patents

Paradigme de traitement pour un traitement combiné d'anticorps anti-cd19 et de venetoclax

Info

Publication number
MA48751A
MA48751A MA048751A MA48751A MA48751A MA 48751 A MA48751 A MA 48751A MA 048751 A MA048751 A MA 048751A MA 48751 A MA48751 A MA 48751A MA 48751 A MA48751 A MA 48751A
Authority
MA
Morocco
Prior art keywords
treatment
venetoclax
antibodies
paradigm
combined
Prior art date
Application number
MA048751A
Other languages
English (en)
Other versions
MA48751B1 (fr
Inventor
Steffen Heeger
Peter Kelemen
Michael Schwarz
Dominika Weinelt
Mark Winderlich
Original Assignee
Morphosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag filed Critical Morphosys Ag
Publication of MA48751A publication Critical patent/MA48751A/fr
Publication of MA48751B1 publication Critical patent/MA48751B1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
MA48751A 2017-05-31 2018-05-30 Paradigme de traitement d'anticorps anti-cd19 et traitement de combinaison venetoclax MA48751B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17173712 2017-05-31
PCT/EP2018/064229 WO2018220040A1 (fr) 2017-05-31 2018-05-30 Paradigme de traitement pour un traitement combiné d'anticorps anti-cd19 et de venetoclax

Publications (2)

Publication Number Publication Date
MA48751A true MA48751A (fr) 2020-04-08
MA48751B1 MA48751B1 (fr) 2023-11-30

Family

ID=59070416

Family Applications (1)

Application Number Title Priority Date Filing Date
MA48751A MA48751B1 (fr) 2017-05-31 2018-05-30 Paradigme de traitement d'anticorps anti-cd19 et traitement de combinaison venetoclax

Country Status (24)

Country Link
EP (2) EP4268900A3 (fr)
JP (2) JP7399713B2 (fr)
KR (2) KR20240117655A (fr)
CN (1) CN110678201A (fr)
AU (1) AU2018276384A1 (fr)
BR (1) BR112019025034A2 (fr)
CA (1) CA3062400A1 (fr)
DK (1) DK3630177T5 (fr)
ES (1) ES2961940T3 (fr)
FI (1) FI3630177T3 (fr)
HR (1) HRP20231229T1 (fr)
HU (1) HUE063119T2 (fr)
IL (2) IL270855B2 (fr)
LT (1) LT3630177T (fr)
MA (1) MA48751B1 (fr)
MD (1) MD3630177T2 (fr)
MX (2) MX2019014330A (fr)
PL (1) PL3630177T3 (fr)
PT (1) PT3630177T (fr)
RS (1) RS64746B1 (fr)
SG (1) SG11201909715VA (fr)
SI (1) SI3630177T1 (fr)
WO (1) WO2018220040A1 (fr)
ZA (1) ZA201907369B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3203587A1 (fr) * 2020-11-30 2022-06-02 Incyte Corporation Polytherapie faisant appel a un anticorps anti-cd19 et a du parsaclisib
WO2022115120A1 (fr) * 2020-11-30 2022-06-02 Incyte Corporation Polythérapie comprenant un anticorps anti-cd19 et le parsaclisib

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2534639C (fr) 2003-07-31 2013-07-30 Immunomedics, Inc. Anticorps anti-cd19
US7902338B2 (en) 2003-07-31 2011-03-08 Immunomedics, Inc. Anti-CD19 antibodies
EP1899379B1 (fr) 2005-06-20 2018-04-11 E. R. Squibb & Sons, L.L.C. Anticorps cd19 et utilisations
EP2270050B1 (fr) 2005-12-30 2013-06-05 Merck Patent GmbH Anticorps anti-CD19 avec une immunogénicité réduite
ES2402591T3 (es) 2006-08-14 2013-05-07 Xencor Inc. Anticuerpos optimizados que seleccionan como diana CD19
EP2066349B1 (fr) 2006-09-08 2012-03-28 MedImmune, LLC Anticorps anti-cd19 humanises et leur utilisation dans le traitement des tumeurs, de la transplantation et des maladies auto-immunes
LT2211904T (lt) 2007-10-19 2016-11-25 Seattle Genetics, Inc. Cd19 surišantys agentai ir jų panaudojimas
US8679492B2 (en) 2009-02-23 2014-03-25 Glenmark Pharmaceuticals S.A. Humanized antibodies that bind to CD19 and their uses
US8546399B2 (en) 2009-05-26 2013-10-01 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
HUE058855T2 (hu) * 2011-08-16 2022-09-28 Morphosys Ag Kombinációs terápia, CD19 elleni ellenanyag és purinanalóg alkalmazásával
KR20200058583A (ko) * 2011-08-16 2020-05-27 모르포시스 아게 항-cd19 항체 및 질소 머스타드를 사용한 조합 요법
WO2017032679A1 (fr) 2015-08-21 2017-03-02 Morphosys Ag Combinaisons et utilisations de celles-ci
LT3532098T (lt) * 2016-10-28 2021-06-25 Morphosys Ag Anti cd19 antikūno derinys su bcl-2 inhibitoriumi, ir jo naudojimas

Also Published As

Publication number Publication date
LT3630177T (lt) 2023-10-25
IL297461A (en) 2022-12-01
FI3630177T3 (fi) 2023-10-18
HRP20231229T1 (hr) 2024-02-02
KR20240117655A (ko) 2024-08-01
IL270855B2 (en) 2023-03-01
JP2024028865A (ja) 2024-03-05
SI3630177T1 (sl) 2023-12-29
WO2018220040A1 (fr) 2018-12-06
ZA201907369B (en) 2024-04-24
MX2023013228A (es) 2024-04-16
MD3630177T2 (ro) 2024-01-31
KR20200010472A (ko) 2020-01-30
JP2020521777A (ja) 2020-07-27
HUE063119T2 (hu) 2024-01-28
IL270855B (en) 2022-11-01
EP4268900A2 (fr) 2023-11-01
JP7399713B2 (ja) 2023-12-18
DK3630177T5 (da) 2024-09-02
RU2019139552A (ru) 2021-07-01
AU2018276384A1 (en) 2019-11-07
SG11201909715VA (en) 2019-11-28
RS64746B1 (sr) 2023-11-30
IL297461B1 (en) 2024-05-01
RU2019139552A3 (fr) 2021-09-22
CA3062400A1 (fr) 2018-12-06
MX2019014330A (es) 2020-02-05
CN110678201A (zh) 2020-01-10
EP3630177A1 (fr) 2020-04-08
BR112019025034A2 (pt) 2020-06-30
DK3630177T3 (da) 2023-10-16
IL270855A (en) 2020-01-30
IL297461B2 (en) 2024-09-01
MA48751B1 (fr) 2023-11-30
EP3630177B1 (fr) 2023-08-09
ES2961940T3 (es) 2024-03-14
EP4268900A3 (fr) 2024-03-06
PL3630177T3 (pl) 2024-04-08
PT3630177T (pt) 2023-11-10

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