MA51677A - Méthodes de traitement du cancer à l'aide d'anticorps anti-pd-1 - Google Patents

Méthodes de traitement du cancer à l'aide d'anticorps anti-pd-1

Info

Publication number
MA51677A
MA51677A MA051677A MA51677A MA51677A MA 51677 A MA51677 A MA 51677A MA 051677 A MA051677 A MA 051677A MA 51677 A MA51677 A MA 51677A MA 51677 A MA51677 A MA 51677A
Authority
MA
Morocco
Prior art keywords
antibodies
cancer treatment
treatment methods
cancer
methods
Prior art date
Application number
MA051677A
Other languages
English (en)
Inventor
Edward F Attiyeh
Kyounghwa Bae
James G Greger
Christina Lourdes Mayer
Hong Xie
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MA51677A publication Critical patent/MA51677A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MA051677A 2018-01-22 2019-01-19 Méthodes de traitement du cancer à l'aide d'anticorps anti-pd-1 MA51677A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862620106P 2018-01-22 2018-01-22
US201962794195P 2019-01-18 2019-01-18

Publications (1)

Publication Number Publication Date
MA51677A true MA51677A (fr) 2020-12-02

Family

ID=65529735

Family Applications (1)

Application Number Title Priority Date Filing Date
MA051677A MA51677A (fr) 2018-01-22 2019-01-19 Méthodes de traitement du cancer à l'aide d'anticorps anti-pd-1

Country Status (16)

Country Link
US (1) US20190225689A1 (fr)
EP (1) EP3743159A2 (fr)
JP (1) JP2021511341A (fr)
KR (1) KR20200112867A (fr)
CN (1) CN111629788A (fr)
AU (1) AU2019208537A1 (fr)
BR (1) BR112020014618A2 (fr)
CA (1) CA3089174A1 (fr)
IL (1) IL275897A (fr)
JO (1) JOP20200177A1 (fr)
MA (1) MA51677A (fr)
MX (1) MX2020007748A (fr)
PH (1) PH12020500576A1 (fr)
SG (1) SG11202006422PA (fr)
WO (1) WO2019142149A2 (fr)
ZA (1) ZA202005223B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4076385A1 (fr) 2019-12-20 2022-10-26 Formycon AG Formulations d'anticorps anti-pd1
TW202140012A (zh) 2020-02-12 2021-11-01 比利時商健生藥品公司 用於治療尿路上皮癌的fgfr酪胺酸激酶抑制劑和抗pd1藥劑
KR20230035236A (ko) 2020-05-07 2023-03-13 아도알엑스 테라퓨틱스 리미티드 아데노신 a2a 수용체의 길항제
GB202011996D0 (en) 2020-07-31 2020-09-16 Adorx Therapeutics Ltd Antagonist compounds
CN112194723B (zh) * 2020-09-25 2021-09-21 广州百吉生物制药有限公司 一种免疫细胞在治疗癌症中应用
GB202019622D0 (en) 2020-12-11 2021-01-27 Adorx Therapeutics Ltd Antagonist compounds
WO2022258011A1 (fr) * 2021-06-11 2022-12-15 广东菲鹏制药股份有限公司 Anticorps humanisé anti-pd-1 ou fragment de liaison à l'antigène de celui-ci et utilisation associée
MX2023014616A (es) 2021-06-23 2024-01-30 Formycon Ag Formulaciones de anticuerpos anti-pd1.
GB2615307A (en) 2022-01-28 2023-08-09 Adorx Therapeutics Ltd Antagonist compounds
WO2024133625A1 (fr) 2022-12-21 2024-06-27 Formycon Ag Formulations d'anticorps anti-pd1
WO2024171082A1 (fr) 2023-02-16 2024-08-22 Sun Pharmaceutical Industries Limited Compositions de protéines stables d'anticorps anti-pd1

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
DE3785186T2 (de) 1986-09-02 1993-07-15 Enzon Lab Inc Bindungsmolekuele mit einzelpolypeptidkette.
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US6255458B1 (en) 1990-08-29 2001-07-03 Genpharm International High affinity human antibodies and human antibodies against digoxin
WO1992022653A1 (fr) 1991-06-14 1992-12-23 Genentech, Inc. Procede de production d'anticorps humanises
WO1994013804A1 (fr) 1992-12-04 1994-06-23 Medical Research Council Proteines de liaison multivalentes et multispecifiques, leur fabrication et leur utilisation
AUPO591797A0 (en) 1997-03-27 1997-04-24 Commonwealth Scientific And Industrial Research Organisation High avidity polyvalent and polyspecific reagents
US6818749B1 (en) 1998-10-31 2004-11-16 The United States Of America As Represented By The Department Of Health And Human Services Variants of humanized anti carcinoma monoclonal antibody cc49
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
PT1354034E (pt) 2000-11-30 2008-02-28 Medarex Inc Roedores transgénicos transcromossómicos para produção de anticorpos humanos
JP2005538706A (ja) 2001-07-12 2005-12-22 ジェファーソン フーテ, スーパーヒト化抗体
CA2642270A1 (fr) * 2006-02-15 2007-08-23 Imclone Systems Incorporated Formulation d'anticorps
US8748356B2 (en) 2007-10-19 2014-06-10 Janssen Biotech, Inc. Methods for use in human-adapting monoclonal antibodies
AU2008343589A1 (en) 2007-12-19 2009-07-09 Centocor Ortho Biotech Inc. Design and generation of human de novo pIX phage display libraries via fusion to pIX or pVII, vectors, antibodies and methods
JP2012505654A (ja) 2008-10-14 2012-03-08 ヤンセン バイオテツク,インコーポレーテツド 抗体をヒト化及び親和性成熟する方法
WO2013112438A1 (fr) * 2012-01-23 2013-08-01 Regeneron Pharmaceuticals, Inc. Formulations stabilisées contenant des anticorps anti-ang2
US20140227250A1 (en) * 2012-08-23 2014-08-14 Merck Sharp & Dohme Corp. Stable formulations of antibodies to tslp
JP6868394B2 (ja) * 2014-05-16 2021-05-12 ファイザー・インク 二重特異性抗体
US20180155429A1 (en) * 2015-05-28 2018-06-07 Bristol-Myers Squibb Company Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody
MX2018003713A (es) * 2015-09-24 2018-08-15 Teva Pharmaceuticals Int Gmbh Prevencion, tratamiento y reduccion del dolor de cabeza postraumatico (persistente).
WO2017055966A1 (fr) * 2015-10-01 2017-04-06 Pfizer Inc. Compositions d'anticorps à faible viscosité
SG11201803520PA (en) * 2015-11-03 2018-05-30 Janssen Biotech Inc Antibodies specifically binding pd-1 and their uses
BR112018014150A2 (pt) * 2016-01-11 2018-12-11 Novartis Ag anticorpos monoclonais humanizados imunoestimulantes contra interleucina-2 humana, e proteínas de fusão dos mesmos
KR102515509B1 (ko) * 2016-06-03 2023-03-28 브리스톨-마이어스 스큅 컴퍼니 결장직장암을 갖는 환자의 치료에서의 항-pd-1 항체의 용도
CN110799245B (zh) 2017-05-16 2022-08-09 生物医学谷探索股份有限公司 用于治疗具有非典型braf突变的癌症的组合物和方法

Also Published As

Publication number Publication date
US20190225689A1 (en) 2019-07-25
SG11202006422PA (en) 2020-08-28
WO2019142149A3 (fr) 2019-09-26
BR112020014618A2 (pt) 2020-12-08
AU2019208537A1 (en) 2020-07-09
EP3743159A2 (fr) 2020-12-02
ZA202005223B (en) 2022-03-30
CA3089174A1 (fr) 2019-07-25
WO2019142149A2 (fr) 2019-07-25
IL275897A (en) 2020-08-31
JP2021511341A (ja) 2021-05-06
CN111629788A (zh) 2020-09-04
JOP20200177A1 (ar) 2020-07-19
MX2020007748A (es) 2020-09-25
KR20200112867A (ko) 2020-10-05
PH12020500576A1 (en) 2021-05-17

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