RS64746B1 - Paradigma lečenja za kombinovani tretman anti-cd19 antitelima i venetoklaksom - Google Patents

Paradigma lečenja za kombinovani tretman anti-cd19 antitelima i venetoklaksom

Info

Publication number
RS64746B1
RS64746B1 RS20230937A RSP20230937A RS64746B1 RS 64746 B1 RS64746 B1 RS 64746B1 RS 20230937 A RS20230937 A RS 20230937A RS P20230937 A RSP20230937 A RS P20230937A RS 64746 B1 RS64746 B1 RS 64746B1
Authority
RS
Serbia
Prior art keywords
treatment
antibody
paradigm
venetoclax combination
venetoclax
Prior art date
Application number
RS20230937A
Other languages
English (en)
Inventor
Peter Kelemen
Michael Schwarz
Mark Winderlich
Steffen Heeger
Dominika Weinelt
Original Assignee
Morphosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag filed Critical Morphosys Ag
Publication of RS64746B1 publication Critical patent/RS64746B1/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
RS20230937A 2017-05-31 2018-05-30 Paradigma lečenja za kombinovani tretman anti-cd19 antitelima i venetoklaksom RS64746B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17173712 2017-05-31
EP18728153.0A EP3630177B1 (en) 2017-05-31 2018-05-30 Treatment paradigm for an anti-cd19 antibody and venetoclax combination treatment
PCT/EP2018/064229 WO2018220040A1 (en) 2017-05-31 2018-05-30 Treatment paradigm for an anti-cd19 antibody and venetoclax combination treatment

Publications (1)

Publication Number Publication Date
RS64746B1 true RS64746B1 (sr) 2023-11-30

Family

ID=59070416

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20230937A RS64746B1 (sr) 2017-05-31 2018-05-30 Paradigma lečenja za kombinovani tretman anti-cd19 antitelima i venetoklaksom

Country Status (24)

Country Link
EP (2) EP4268900A3 (sr)
JP (2) JP7399713B2 (sr)
KR (1) KR20200010472A (sr)
CN (1) CN110678201A (sr)
AU (1) AU2018276384A1 (sr)
BR (1) BR112019025034A2 (sr)
CA (1) CA3062400A1 (sr)
DK (1) DK3630177T3 (sr)
ES (1) ES2961940T3 (sr)
FI (1) FI3630177T3 (sr)
HR (1) HRP20231229T1 (sr)
HU (1) HUE063119T2 (sr)
IL (2) IL297461B1 (sr)
LT (1) LT3630177T (sr)
MA (1) MA48751B1 (sr)
MD (1) MD3630177T2 (sr)
MX (1) MX2019014330A (sr)
PL (1) PL3630177T3 (sr)
PT (1) PT3630177T (sr)
RS (1) RS64746B1 (sr)
SG (1) SG11201909715VA (sr)
SI (1) SI3630177T1 (sr)
WO (1) WO2018220040A1 (sr)
ZA (1) ZA201907369B (sr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220241411A1 (en) * 2020-11-30 2022-08-04 Incyte Corporation Combination therapy with an anti-cd19 antibody and parsaclisib
WO2022115120A1 (en) * 2020-11-30 2022-06-02 Incyte Corporation Combination therapy with an anti-cd19 antibody and parsaclisib

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7902338B2 (en) 2003-07-31 2011-03-08 Immunomedics, Inc. Anti-CD19 antibodies
WO2005012493A2 (en) 2003-07-31 2005-02-10 Immunomedics, Inc. Anti-cd19 antibodies
EA200800094A1 (ru) 2005-06-20 2008-06-30 Медарекс, Инк. Антитела cd19 и их использование
KR101397290B1 (ko) 2005-12-30 2014-05-21 메르크 파텐트 게엠베하 감소한 면역원성을 가지는 항-cd19 항체
SI2059536T1 (sl) 2006-08-14 2014-06-30 Xencor, Inc. Optimirana protitelesa, ki ciljajo CD19
PT2066349E (pt) 2006-09-08 2012-07-02 Medimmune Llc Anticorpos anti-cd19 humanizados e respectiva utilização no tratamento de tumores, transplantação e doenças auto-imunes
EP2211904B1 (en) 2007-10-19 2016-08-17 Seattle Genetics, Inc. Cd19 binding agents and uses thereof
KR20110122859A (ko) 2009-02-23 2011-11-11 그렌마크 파머수티칼스 에스. 아. Cd19에 결합하는 인간화된 항체 및 그것의 용도
US8546399B2 (en) 2009-05-26 2013-10-01 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
ES2909722T3 (es) * 2011-08-16 2022-05-10 Morphosys Ag Terapia de combinación con un anticuerpo anti-CD19 y una mostaza nitrogenada
EP4083071A3 (en) * 2011-08-16 2023-02-22 MorphoSys AG Combination therapy with an anti-cd19 antibody and a purine analog
CN107921129B (zh) 2015-08-21 2022-05-27 莫佛塞斯公司 组合及其用途
AU2017348624A1 (en) * 2016-10-28 2019-03-28 Incyte Corporation Combination of anti CD19 antibody with a BCL-2 inhibitor and uses thereof

Also Published As

Publication number Publication date
EP3630177B1 (en) 2023-08-09
ZA201907369B (en) 2024-04-24
CN110678201A (zh) 2020-01-10
DK3630177T3 (da) 2023-10-16
EP4268900A3 (en) 2024-03-06
PT3630177T (pt) 2023-11-10
RU2019139552A (ru) 2021-07-01
HUE063119T2 (hu) 2024-01-28
IL270855B2 (en) 2023-03-01
CA3062400A1 (en) 2018-12-06
SI3630177T1 (sl) 2023-12-29
WO2018220040A1 (en) 2018-12-06
MX2019014330A (es) 2020-02-05
JP7399713B2 (ja) 2023-12-18
JP2024028865A (ja) 2024-03-05
JP2020521777A (ja) 2020-07-27
LT3630177T (lt) 2023-10-25
IL297461B1 (en) 2024-05-01
KR20200010472A (ko) 2020-01-30
MA48751A (fr) 2020-04-08
AU2018276384A1 (en) 2019-11-07
IL270855A (en) 2020-01-30
MD3630177T2 (ro) 2024-01-31
IL297461A (en) 2022-12-01
FI3630177T3 (fi) 2023-10-18
SG11201909715VA (en) 2019-11-28
PL3630177T3 (pl) 2024-04-08
BR112019025034A2 (pt) 2020-06-30
HRP20231229T1 (hr) 2024-02-02
EP3630177A1 (en) 2020-04-08
IL270855B (en) 2022-11-01
RU2019139552A3 (sr) 2021-09-22
MA48751B1 (fr) 2023-11-30
ES2961940T3 (es) 2024-03-14
EP4268900A2 (en) 2023-11-01

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