MA47290A - Combinaison d'un agoniste sélectif de l'il-2rbeta et d'un agoniste de l'il-15 à action prolongée - Google Patents

Combinaison d'un agoniste sélectif de l'il-2rbeta et d'un agoniste de l'il-15 à action prolongée

Info

Publication number
MA47290A
MA47290A MA047290A MA47290A MA47290A MA 47290 A MA47290 A MA 47290A MA 047290 A MA047290 A MA 047290A MA 47290 A MA47290 A MA 47290A MA 47290 A MA47290 A MA 47290A
Authority
MA
Morocco
Prior art keywords
agonist
2rbeta
selective
action
combination
Prior art date
Application number
MA047290A
Other languages
English (en)
Inventor
Deborah Charych
Peter Kirk
Original Assignee
Nektar Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nektar Therapeutics filed Critical Nektar Therapeutics
Publication of MA47290A publication Critical patent/MA47290A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2086—IL-13 to IL-16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
MA047290A 2015-10-08 2016-10-07 Combinaison d'un agoniste sélectif de l'il-2rbeta et d'un agoniste de l'il-15 à action prolongée MA47290A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562239207P 2015-10-08 2015-10-08

Publications (1)

Publication Number Publication Date
MA47290A true MA47290A (fr) 2019-11-27

Family

ID=57249859

Family Applications (1)

Application Number Title Priority Date Filing Date
MA047290A MA47290A (fr) 2015-10-08 2016-10-07 Combinaison d'un agoniste sélectif de l'il-2rbeta et d'un agoniste de l'il-15 à action prolongée

Country Status (12)

Country Link
US (1) US20180296645A1 (fr)
EP (1) EP3359182B1 (fr)
JP (3) JP7407511B2 (fr)
KR (1) KR20180063184A (fr)
CN (1) CN108135978A (fr)
AU (1) AU2016335860B2 (fr)
CA (1) CA3000211A1 (fr)
HK (1) HK1253347A1 (fr)
IL (1) IL258456B (fr)
MA (1) MA47290A (fr)
MX (1) MX2018004296A (fr)
WO (1) WO2017062832A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7316222B2 (ja) * 2017-05-15 2023-07-27 ネクター セラピューティクス 長時間作用型インターロイキン－１５受容体作動薬並びに関連する免疫治療組成物及び方法
US11248025B2 (en) 2019-06-03 2022-02-15 Medikine, Inc. IL-2alpha receptor subunit binding compounds
WO2023133595A2 (fr) 2022-01-10 2023-07-13 Sana Biotechnology, Inc. Méthodes de dosage et d'administration ex vivo de particules lipidiques ou de vecteurs viraux ainsi que systèmes et utilisations associés
WO2023193015A1 (fr) 2022-04-01 2023-10-05 Sana Biotechnology, Inc. Polythérapies d'agoniste de récepteur de cytokine et de vecteur viral

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6077519A (en) * 1993-01-29 2000-06-20 University Of Pittsburgh Methods for isolation and use of T cell epitopes eluted from viable cells in vaccines for treating cancer patients
US6110721A (en) * 1993-11-12 2000-08-29 Gilead Sciences, Inc. Polypeptides and coagulation therapy
US20050069521A1 (en) * 2003-08-28 2005-03-31 Emd Lexigen Research Center Corp. Enhancing the circulating half-life of interleukin-2 proteins
JP4560629B2 (ja) * 2005-03-31 2010-10-13 国立大学法人 筑波大学 腫瘍壊死誘導療法の抗腫瘍効果増強剤
US20060257361A1 (en) * 2005-04-12 2006-11-16 Government Of The Us, As Represented By The Secretary, Department Of Health And Human Services Novel form of interleukin-15, Fc-IL-15, and methods of use
WO2006138572A2 (fr) 2005-06-16 2006-12-28 Nektar Therapeutics Al, Corporation Conjugues a liaison degradable et reactifs polymeres utilises dans la preparation de ces conjugues
JP5244610B2 (ja) * 2005-12-21 2013-07-24 セントクローネ インターナショナル エービー ガン患者の免疫療法用腫瘍反応性ｔリンパ球の改良拡大法
BRPI0720619B1 (pt) * 2006-12-27 2022-04-05 Nektar Therapeutics Composto de fator ix-poli(etileno glicol) com uma ligação liberável, método para preparar o mesmo e composição
WO2009135031A1 (fr) * 2008-04-30 2009-11-05 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic Il-15 substitué
EA037083B1 (ru) * 2010-11-12 2021-02-03 Нектар Терапьютикс Иммуномодулирующий конъюгат, включающий il-2 и водорастворимые полимеры
MX2016010870A (es) * 2014-02-21 2016-10-26 Nektar Therapeutics (India) Pvt Ltd Agonistas il-2rbeta-selectivos en combinacion con un anticuerpo anti-ctla-4 o un anticuerpo anti-pd-1.
MA39711A (fr) 2014-04-03 2015-10-08 Nektar Therapeutics Conjugués d'une fraction d'il-15 et d'un polymère

Also Published As

Publication number Publication date
AU2016335860A1 (en) 2018-04-12
KR20180063184A (ko) 2018-06-11
JP2021066748A (ja) 2021-04-30
IL258456A (en) 2018-06-28
JP2018530568A (ja) 2018-10-18
CA3000211A1 (fr) 2017-04-13
CN108135978A (zh) 2018-06-08
IL258456B (en) 2021-07-29
JP2023099731A (ja) 2023-07-13
EP3359182A1 (fr) 2018-08-15
MX2018004296A (es) 2018-08-01
HK1253347A1 (zh) 2019-06-14
US20180296645A1 (en) 2018-10-18
WO2017062832A1 (fr) 2017-04-13
JP7407511B2 (ja) 2024-01-04
AU2016335860B2 (en) 2023-08-10
EP3359182B1 (fr) 2023-04-19

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