MA46750A - Méthodes de traitement de l'htap à l'aide de combinaisons de ralinepag et d'autres agents - Google Patents
Méthodes de traitement de l'htap à l'aide de combinaisons de ralinepag et d'autres agentsInfo
- Publication number
- MA46750A MA46750A MA046750A MA46750A MA46750A MA 46750 A MA46750 A MA 46750A MA 046750 A MA046750 A MA 046750A MA 46750 A MA46750 A MA 46750A MA 46750 A MA46750 A MA 46750A
- Authority
- MA
- Morocco
- Prior art keywords
- ralinepag
- agents
- combinations
- methods
- treating pah
- Prior art date
Links
- NPDKXVKJRHPDQT-UHFFFAOYSA-N 2-[[4-[[(4-chlorophenyl)-phenylcarbamoyl]oxymethyl]cyclohexyl]methoxy]acetic acid Chemical compound C1CC(COCC(=O)O)CCC1COC(=O)N(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 NPDKXVKJRHPDQT-UHFFFAOYSA-N 0.000 title 1
- 229950005114 ralinepag Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5578—Eicosanoids, e.g. leukotrienes or prostaglandins having a pentalene ring system, e.g. carbacyclin, iloprost
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662420515P | 2016-11-10 | 2016-11-10 | |
US201762530533P | 2017-07-10 | 2017-07-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA46750A true MA46750A (fr) | 2019-09-18 |
Family
ID=60451197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA046750A MA46750A (fr) | 2016-11-10 | 2017-11-10 | Méthodes de traitement de l'htap à l'aide de combinaisons de ralinepag et d'autres agents |
Country Status (10)
Country | Link |
---|---|
US (1) | US20190321328A1 (fr) |
EP (1) | EP3538154A1 (fr) |
JP (2) | JP2019533713A (fr) |
KR (3) | KR20200015439A (fr) |
CN (1) | CN110691612A (fr) |
AU (2) | AU2017357759A1 (fr) |
CA (1) | CA3043283A1 (fr) |
IL (1) | IL266518A (fr) |
MA (1) | MA46750A (fr) |
WO (1) | WO2018089804A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2018227842B2 (en) | 2017-03-01 | 2024-05-02 | Arena Pharmaceuticals, Inc. | Compositions comprising PGI2-receptor agonists and processes for the preparation thereof |
US20210212979A1 (en) * | 2018-05-16 | 2021-07-15 | Arena Pharmaceuticals, Inc. | Compositions comprising pgi2-receptor agonists and processes for the preparation thereof |
CN108721296B (zh) * | 2018-07-03 | 2019-04-05 | 中国人民解放军总医院 | 一种化合物在治疗或预防高原病中的用途 |
CN112638865B (zh) * | 2018-09-06 | 2022-07-26 | 广东东阳光药业有限公司 | 药物共晶体及其制备方法 |
SI3897646T1 (sl) | 2018-12-21 | 2024-08-30 | ACTELION PHARMACEUTICALS lTD, | Makitentan za zdravljenje pljučne arterijske hipertenzije |
TW202042818A (zh) | 2019-01-25 | 2020-12-01 | 瑞士商艾克泰聯製藥有限公司 | 用於治療慢性血栓性肺高血壓之醫藥組成物 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0325291D0 (en) * | 2003-10-29 | 2003-12-03 | Pfizer Ltd | Novel combination |
KR20240024285A (ko) | 2008-03-18 | 2024-02-23 | 아레나 파마슈티칼스, 인크. | 프로스타시클린 (pgi2) 수용체와 관련된 장애의 치료에 유용한 상기 수용체의 조절제 |
EP2480526A1 (fr) * | 2009-09-23 | 2012-08-01 | Arena Pharmaceuticals, Inc. | Formes cristallines et procédés pour la préparation d'agonistes du récepteur pgi2 |
WO2013040068A2 (fr) * | 2011-09-12 | 2013-03-21 | Irix Pharmaceuticals, Inc. | Procédé de préparation de prostacyclines synthétiques |
AU2013351934B2 (en) * | 2012-11-30 | 2018-03-29 | Insmed Incorporated | Prostacylin compositions and methods for using the same |
CN114452279A (zh) * | 2014-10-23 | 2022-05-10 | 艾尼纳制药公司 | 治疗与pgi2受体相关的病症的方法 |
US20180325875A1 (en) * | 2015-01-13 | 2018-11-15 | Vivus, Inc. | Combination therapy for pulmonary hypertension |
-
2017
- 2017-11-10 JP JP2019524887A patent/JP2019533713A/ja active Pending
- 2017-11-10 MA MA046750A patent/MA46750A/fr unknown
- 2017-11-10 KR KR1020197016623A patent/KR20200015439A/ko active Application Filing
- 2017-11-10 US US16/348,665 patent/US20190321328A1/en active Pending
- 2017-11-10 CN CN201780082981.0A patent/CN110691612A/zh active Pending
- 2017-11-10 WO PCT/US2017/061116 patent/WO2018089804A1/fr unknown
- 2017-11-10 EP EP17804042.4A patent/EP3538154A1/fr active Pending
- 2017-11-10 CA CA3043283A patent/CA3043283A1/fr active Pending
- 2017-11-10 AU AU2017357759A patent/AU2017357759A1/en not_active Abandoned
- 2017-11-10 KR KR1020247014676A patent/KR20240068077A/ko active Search and Examination
- 2017-11-10 KR KR1020237003653A patent/KR20230021186A/ko active Application Filing
-
2019
- 2019-05-08 IL IL266518A patent/IL266518A/en unknown
-
2022
- 2022-11-21 JP JP2022185917A patent/JP2023029865A/ja active Pending
-
2023
- 2023-11-09 AU AU2023263497A patent/AU2023263497A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
KR20240068077A (ko) | 2024-05-17 |
KR20200015439A (ko) | 2020-02-12 |
WO2018089804A1 (fr) | 2018-05-17 |
CA3043283A1 (fr) | 2018-05-17 |
CN110691612A (zh) | 2020-01-14 |
JP2019533713A (ja) | 2019-11-21 |
AU2017357759A1 (en) | 2019-06-06 |
KR20230021186A (ko) | 2023-02-13 |
IL266518A (en) | 2019-07-31 |
WO2018089804A9 (fr) | 2018-06-21 |
EP3538154A1 (fr) | 2019-09-18 |
AU2023263497A1 (en) | 2023-11-30 |
US20190321328A1 (en) | 2019-10-24 |
JP2023029865A (ja) | 2023-03-07 |
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