MA46722A - Modulateurs allostériques positifs du récepteur muscarinique à l'acétylcholine m4 - Google Patents

Modulateurs allostériques positifs du récepteur muscarinique à l'acétylcholine m4

Info

Publication number
MA46722A
MA46722A MA046722A MA46722A MA46722A MA 46722 A MA46722 A MA 46722A MA 046722 A MA046722 A MA 046722A MA 46722 A MA46722 A MA 46722A MA 46722 A MA46722 A MA 46722A
Authority
MA
Morocco
Prior art keywords
acetylcholin
muscarinic
receptor
positive allosteric
allosteric modulators
Prior art date
Application number
MA046722A
Other languages
English (en)
French (fr)
Inventor
Sean R Bollinger
P Jeffrey Conn
Darren W Engers
Julie L Engers
Craig W Lindsley
Original Assignee
Univ Vanderbilt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vanderbilt filed Critical Univ Vanderbilt
Publication of MA46722A publication Critical patent/MA46722A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA046722A 2016-11-07 2017-11-07 Modulateurs allostériques positifs du récepteur muscarinique à l'acétylcholine m4 MA46722A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662418651P 2016-11-07 2016-11-07
US201762542621P 2017-08-08 2017-08-08

Publications (1)

Publication Number Publication Date
MA46722A true MA46722A (fr) 2019-09-11

Family

ID=62076815

Family Applications (1)

Application Number Title Priority Date Filing Date
MA046722A MA46722A (fr) 2016-11-07 2017-11-07 Modulateurs allostériques positifs du récepteur muscarinique à l'acétylcholine m4

Country Status (7)

Country Link
US (1) US11008335B2 (enExample)
EP (1) EP3534901B1 (enExample)
JP (1) JP7098167B2 (enExample)
CN (1) CN109890388B (enExample)
BR (1) BR112018013882A2 (enExample)
MA (1) MA46722A (enExample)
WO (1) WO2018085803A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI3474846T3 (fi) 2016-06-22 2023-02-16 Univ Vanderbilt Muskariinisen asetyylikoliinireseptorin m4 positiiviset allosteeriset modulaattorit
MA47126A (fr) 2016-11-07 2019-10-30 Univ Vanderbilt Modulateurs allostériques positifs du récepteur muscarinique à l'acétylcholine m4
CN109863139B (zh) 2016-11-07 2023-02-17 范德比尔特大学 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂
TW201930311A (zh) 2017-12-05 2019-08-01 泛德比爾特大學 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑
EP3846806A4 (en) 2018-09-04 2022-06-08 Pipeline Therapeutics, Inc. Muscarinic acetylcholine m1 receptor antagonists
CN121378271A (zh) 2019-10-07 2026-01-23 康蒂内乌姆医疗公司 毒蕈碱型乙酰胆碱m1受体拮抗剂
US11752149B2 (en) 2019-12-02 2023-09-12 Pipeline Therapeutics, Inc. Muscarinic acetylcholine M1 receptor antagonists
US20250064833A1 (en) 2021-12-13 2025-02-27 Sage Therapeutics, Inc. Combination of muscarinic receptor positive modulators and nmda positive allosteric modulators

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FI3474846T3 (fi) 2016-06-22 2023-02-16 Univ Vanderbilt Muskariinisen asetyylikoliinireseptorin m4 positiiviset allosteeriset modulaattorit
CN109863139B (zh) 2016-11-07 2023-02-17 范德比尔特大学 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂
MA47126A (fr) 2016-11-07 2019-10-30 Univ Vanderbilt Modulateurs allostériques positifs du récepteur muscarinique à l'acétylcholine m4

Also Published As

Publication number Publication date
JP2019537592A (ja) 2019-12-26
EP3534901A1 (en) 2019-09-11
BR112018013882A2 (pt) 2018-12-18
WO2018085803A1 (en) 2018-05-11
US20200181166A1 (en) 2020-06-11
EP3534901B1 (en) 2022-06-22
CN109890388B (zh) 2023-03-28
US11008335B2 (en) 2021-05-18
CN109890388A (zh) 2019-06-14
EP3534901A4 (en) 2020-04-22
JP7098167B2 (ja) 2022-07-11

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