MA43738A - Anticorps anti-tnfalpha et leurs fragments fonctionnels - Google Patents

Anticorps anti-tnfalpha et leurs fragments fonctionnels

Info

Publication number
MA43738A
MA43738A MA043738A MA43738A MA43738A MA 43738 A MA43738 A MA 43738A MA 043738 A MA043738 A MA 043738A MA 43738 A MA43738 A MA 43738A MA 43738 A MA43738 A MA 43738A
Authority
MA
Morocco
Prior art keywords
functional fragments
tnfalpha antibodies
tnfalpha
antibodies
fragments
Prior art date
Application number
MA043738A
Other languages
English (en)
Inventor
Esther Maria Furrer
Tea Gunde
Sebastian Meyer
Original Assignee
Tillotts Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tillotts Pharma Ag filed Critical Tillotts Pharma Ag
Publication of MA43738A publication Critical patent/MA43738A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/626—Diabody or triabody
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MA043738A 2016-03-17 2017-03-16 Anticorps anti-tnfalpha et leurs fragments fonctionnels MA43738A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16160918.5A EP3219727B1 (fr) 2016-03-17 2016-03-17 Anticorps anti-tnf alpha et fragments fonctionnels de ceux-ci

Publications (1)

Publication Number Publication Date
MA43738A true MA43738A (fr) 2018-11-28

Family

ID=55542579

Family Applications (1)

Application Number Title Priority Date Filing Date
MA043738A MA43738A (fr) 2016-03-17 2017-03-16 Anticorps anti-tnfalpha et leurs fragments fonctionnels

Country Status (26)

Country Link
US (1) US10975143B2 (fr)
EP (2) EP3219727B1 (fr)
JP (1) JP7126485B2 (fr)
KR (1) KR102474765B1 (fr)
CN (1) CN109071651B (fr)
AR (1) AR107916A1 (fr)
BR (1) BR112018067713A2 (fr)
CA (1) CA3011786A1 (fr)
CY (1) CY1123781T1 (fr)
DK (1) DK3219727T3 (fr)
EA (1) EA201892097A1 (fr)
ES (1) ES2843974T3 (fr)
HR (1) HRP20210120T1 (fr)
HU (1) HUE052869T2 (fr)
IL (1) IL261140B2 (fr)
JO (1) JOP20170063B1 (fr)
LT (1) LT3219727T (fr)
MA (1) MA43738A (fr)
PL (1) PL3219727T3 (fr)
PT (1) PT3219727T (fr)
RS (1) RS61412B1 (fr)
SG (1) SG11202000029PA (fr)
SI (1) SI3219727T1 (fr)
TW (1) TWI758280B (fr)
UY (1) UY37158A (fr)
WO (1) WO2017158097A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017158079A1 (fr) 2016-03-17 2017-09-21 Numab Innovation Ag Anticorps anti-tnfα et fragments fonctionnels correspondants
SI3219726T1 (sl) 2016-03-17 2021-02-26 Tillotts Pharma Ag Anti-TNF alfa protitelesa in njihovi funkcionalni fragmenti
EP3430042B1 (fr) 2016-03-17 2023-05-24 Numab Innovation AG Anticorps anti-tnf alpha et fragments fonctionnels de ceux-ci
BR112019011689A2 (pt) 2016-12-14 2019-10-22 Progenity Inc tratamento de uma doença do trato gastrointestinal com um inibidor de tnf
EP3592384A1 (fr) * 2017-03-09 2020-01-15 MAB Discovery GmbH Anticorps se liant spécifiquement à il-1r7 humain
WO2019246313A1 (fr) 2018-06-20 2019-12-26 Progenity, Inc. Traitement d'une maladie du tractus gastro-intestinal avec un inhibiteur du tnf
US20220056124A1 (en) * 2018-09-05 2022-02-24 The Board Of Regents Of The University Of Texas System Monoclonal antibodies against endotrophin and the use thereof
KR20210095165A (ko) 2018-11-19 2021-07-30 프로제너티, 인크. 바이오의약품으로 질환을 치료하기 위한 방법 및 디바이스
WO2020114616A1 (fr) 2018-12-07 2020-06-11 Tillotts Pharma Ag Traitement topique d'une diarrhée, d'une colite ou d'une entérocolite induite par un inhibiteur de point de contrôle immunitaire au moyen d'anticorps et de fragments de ceux-ci
CN115666704A (zh) 2019-12-13 2023-01-31 比奥拉治疗股份有限公司 用于将治疗剂递送至胃肠道的可摄取装置

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WO2017158079A1 (fr) 2016-03-17 2017-09-21 Numab Innovation Ag Anticorps anti-tnfα et fragments fonctionnels correspondants
EP3430042B1 (fr) 2016-03-17 2023-05-24 Numab Innovation AG Anticorps anti-tnf alpha et fragments fonctionnels de ceux-ci

Also Published As

Publication number Publication date
EP3219727B1 (fr) 2020-12-16
CN109071651A (zh) 2018-12-21
EA201892097A1 (ru) 2019-02-28
WO2017158097A1 (fr) 2017-09-21
IL261140B2 (en) 2023-04-01
JP2019512269A (ja) 2019-05-16
UY37158A (es) 2017-10-31
EP3430045B1 (fr) 2023-08-23
DK3219727T3 (da) 2021-01-04
US20200299375A1 (en) 2020-09-24
US10975143B2 (en) 2021-04-13
KR102474765B1 (ko) 2022-12-06
BR112018067713A2 (pt) 2019-01-08
PL3219727T3 (pl) 2021-05-17
HUE052869T2 (hu) 2021-05-28
AR107916A1 (es) 2018-06-28
TW201739765A (zh) 2017-11-16
IL261140B (en) 2022-12-01
JP7126485B2 (ja) 2022-08-26
ES2843974T3 (es) 2021-07-21
SI3219727T1 (sl) 2021-04-30
EP3219727A1 (fr) 2017-09-20
CA3011786A1 (fr) 2017-09-21
RS61412B1 (sr) 2021-03-31
KR20180118671A (ko) 2018-10-31
HRP20210120T1 (hr) 2021-03-05
JOP20170063B1 (ar) 2021-08-17
CN109071651B (zh) 2022-08-30
EP3430045A1 (fr) 2019-01-23
CY1123781T1 (el) 2022-05-27
PT3219727T (pt) 2021-01-21
LT3219727T (lt) 2021-02-10
IL261140A (en) 2018-10-31
SG11202000029PA (en) 2020-02-27
TWI758280B (zh) 2022-03-21

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