MA43271A - Formulations améliorées de déférasirox et leurs procédés de fabrication - Google Patents

Formulations améliorées de déférasirox et leurs procédés de fabrication

Info

Publication number
MA43271A
MA43271A MA043271A MA43271A MA43271A MA 43271 A MA43271 A MA 43271A MA 043271 A MA043271 A MA 043271A MA 43271 A MA43271 A MA 43271A MA 43271 A MA43271 A MA 43271A
Authority
MA
Morocco
Prior art keywords
improved
manufacturing processes
deferasirox
formulations
deferasirox formulations
Prior art date
Application number
MA043271A
Other languages
English (en)
French (fr)
Inventor
Justin M Keen
Sandra U Kucera
Dave A Miller
Original Assignee
Dispersol Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dispersol Technologies Llc filed Critical Dispersol Technologies Llc
Publication of MA43271A publication Critical patent/MA43271A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/04Chelating agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA043271A 2015-06-17 2016-06-17 Formulations améliorées de déférasirox et leurs procédés de fabrication MA43271A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562180998P 2015-06-17 2015-06-17

Publications (1)

Publication Number Publication Date
MA43271A true MA43271A (fr) 2018-09-26

Family

ID=57546755

Family Applications (1)

Application Number Title Priority Date Filing Date
MA043271A MA43271A (fr) 2015-06-17 2016-06-17 Formulations améliorées de déférasirox et leurs procédés de fabrication

Country Status (10)

Country Link
US (4) US10265301B2 (https=)
EP (1) EP3310354B1 (https=)
JP (1) JP2018517734A (https=)
CN (1) CN107847490A (https=)
AU (3) AU2016280280B2 (https=)
CA (1) CA2989145C (https=)
HK (1) HK1254608A1 (https=)
IL (1) IL256322B (https=)
MA (1) MA43271A (https=)
WO (1) WO2016205658A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2565279B1 (en) 2007-12-05 2014-12-03 Complete Genomics, Inc. Efficient base determination in sequencing reactions
US10098857B2 (en) 2008-10-10 2018-10-16 The Board Of Trustees Of The Leland Stanford Junior University Topical and transdermal delivery of HIF-1 modulators to prevent and treat chronic wounds
EP2977455B1 (en) 2009-06-15 2020-04-15 Complete Genomics, Inc. Method for long fragment read sequencing
US10837879B2 (en) 2011-11-02 2020-11-17 Complete Genomics, Inc. Treatment for stabilizing nucleic acid arrays
CZ2017255A3 (cs) * 2017-05-04 2018-11-14 Zentiva, K.S. Filmem potažené tablety Deferasiroxu
WO2019055490A1 (en) 2017-09-14 2019-03-21 The Board Of Trustees Of The Leland Stanford Junior University PACKAGING OF IRRADIED FABRIC FOR FAT GREETING RETENTION
CN111511365A (zh) * 2017-11-10 2020-08-07 分散技术有限责任公司 改进的药物制剂
WO2020061474A1 (en) * 2018-09-20 2020-03-26 Tautona Group Ip Holding Company, L.L.C. Iron chelating compounds for treating aesthetic skin conditions
EP4096791A1 (en) 2020-01-31 2022-12-07 Nanocopoeia LLC Amorphous nilotinib microparticles and uses thereof
WO2021222739A1 (en) 2020-04-30 2021-11-04 Nanocopoeia, Llc Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib
CN112870361A (zh) * 2021-01-28 2021-06-01 重庆医科大学 铁死亡抑制剂在制备预防或治疗铁过载导致的骨质疏松或骨丢失的药物中的应用
CN116203161A (zh) * 2022-05-30 2023-06-02 上海奥科达医药科技股份有限公司 地拉罗司颗粒剂中相关杂质的检测方法
WO2025151876A1 (en) * 2024-01-11 2025-07-17 Minneamrita Therapeutics Llc Triptolide formulations

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0009056D0 (en) * 2000-04-12 2000-05-31 Nestle Sa Composition comprising free amino acids
BRPI0617715A2 (pt) * 2005-10-19 2011-08-02 Novartis Ag comprimidos dispersìveis compreendendo deferasirox
JP6073043B2 (ja) 2007-08-21 2017-02-01 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム 医薬品適用のための熱−動力学的混合
WO2009067557A1 (en) * 2007-11-19 2009-05-28 Teva Pharmaceutical Industries Ltd. Deferasirox pharmaceutical compositions
US20110097413A1 (en) * 2008-04-21 2011-04-28 Actavis Group Ptc Ehf Solid state forms of deferasirox salts and process for the preparation thereof
AU2010329487A1 (en) * 2009-12-07 2012-06-14 Mapi Pharma Limited Processes for the preparation of deferasirox, and deferasirox polymorphs
ES2543427T3 (es) 2010-07-08 2015-08-19 Ratiopharm Gmbh Forma farmacéutica oral de deferasirox
WO2012025935A2 (en) * 2010-08-25 2012-03-01 Ramamohan Rao Davuluri A process for the preparation of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one and its use for preparation of 4-[3, 5-bis (2-hydroxyphenyl)-1h-1, 2, 4-triazol-1-yl] benzoic acid
MX2013003522A (es) 2010-10-01 2013-05-22 Cipla Ltd Composicion farmaceutica.
WO2012116238A1 (en) * 2011-02-23 2012-08-30 Dispersol Technologies, Llc PHARMACEUTICAL FORMULATIONS OF ACETYL-11-KETO-β-BOSWELLIC ACID, DIINDOLYLMETHANE, AND CURCUMIN FOR PHARMACEUTICAL APPLICATIONS
HRP20190173T1 (hr) 2013-03-08 2019-03-22 Novartis Ag Oralne formulacije deferasiroksa
US20160120847A1 (en) 2013-05-10 2016-05-05 Cipla Limited Low Dose Pharmaceutical Composition

Also Published As

Publication number Publication date
CN107847490A (zh) 2018-03-27
AU2016280280A1 (en) 2018-01-04
US20190167643A1 (en) 2019-06-06
US20240091201A1 (en) 2024-03-21
IL256322B (en) 2022-03-01
AU2021277731A1 (en) 2021-12-23
AU2024202528B2 (en) 2026-01-08
EP3310354A1 (en) 2018-04-25
IL256322A (en) 2018-02-28
EP3310354C0 (en) 2026-02-25
CA2989145A1 (en) 2016-12-22
EP3310354A4 (en) 2018-12-12
AU2024202528A1 (en) 2024-05-09
HK1254608A1 (zh) 2019-07-26
EP3310354B1 (en) 2026-02-25
CA2989145C (en) 2024-10-29
JP2018517734A (ja) 2018-07-05
US10258608B2 (en) 2019-04-16
US11878005B2 (en) 2024-01-23
AU2021277731B2 (en) 2024-04-11
AU2016280280B2 (en) 2021-09-02
US10265301B2 (en) 2019-04-23
WO2016205658A1 (en) 2016-12-22
US20170296514A1 (en) 2017-10-19
US20170027911A1 (en) 2017-02-02

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