HK1254608A1 - 改良的地拉羅司製劑及其製備方法 - Google Patents

改良的地拉羅司製劑及其製備方法

Info

Publication number
HK1254608A1
HK1254608A1 HK18113574.7A HK18113574A HK1254608A1 HK 1254608 A1 HK1254608 A1 HK 1254608A1 HK 18113574 A HK18113574 A HK 18113574A HK 1254608 A1 HK1254608 A1 HK 1254608A1
Authority
HK
Hong Kong
Prior art keywords
deferasirox
making
methods
same
improved formulations
Prior art date
Application number
HK18113574.7A
Other languages
English (en)
Inventor
Dave A Miller
Justin M Keen
Sandra U Kucera
Original Assignee
Dispersol Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dispersol Technologies Llc filed Critical Dispersol Technologies Llc
Publication of HK1254608A1 publication Critical patent/HK1254608A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/04Chelating agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18113574.7A 2015-06-17 2018-10-23 改良的地拉羅司製劑及其製備方法 HK1254608A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562180998P 2015-06-17 2015-06-17
PCT/US2016/038089 WO2016205658A1 (en) 2015-06-17 2016-06-17 Improved formulations of deferasirox and methods of making the same

Publications (1)

Publication Number Publication Date
HK1254608A1 true HK1254608A1 (zh) 2019-07-26

Family

ID=57546755

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18113574.7A HK1254608A1 (zh) 2015-06-17 2018-10-23 改良的地拉羅司製劑及其製備方法

Country Status (10)

Country Link
US (4) US10265301B2 (zh)
EP (1) EP3310354A4 (zh)
JP (1) JP2018517734A (zh)
CN (1) CN107847490A (zh)
AU (3) AU2016280280B2 (zh)
CA (1) CA2989145A1 (zh)
HK (1) HK1254608A1 (zh)
IL (1) IL256322B (zh)
MA (1) MA43271A (zh)
WO (1) WO2016205658A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2610351B1 (en) 2007-12-05 2015-07-08 Complete Genomics, Inc. Efficient base determination in sequencing reactions
US10098857B2 (en) 2008-10-10 2018-10-16 The Board Of Trustees Of The Leland Stanford Junior University Topical and transdermal delivery of HIF-1 modulators to prevent and treat chronic wounds
CA2765427A1 (en) 2009-06-15 2010-12-23 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
US10837879B2 (en) 2011-11-02 2020-11-17 Complete Genomics, Inc. Treatment for stabilizing nucleic acid arrays
CZ2017255A3 (cs) * 2017-05-04 2018-11-14 Zentiva, K.S. Filmem potažené tablety Deferasiroxu
US11331288B2 (en) 2017-09-14 2022-05-17 The Board Of Trustees Of The Leland Stanford Junior University Conditioning irradiated tissue for increasing vascularity
WO2019094688A1 (en) * 2017-11-10 2019-05-16 Dispersol Technologies, Llc Improved drug formulations
CA3113175A1 (en) * 2018-09-20 2020-03-26 Tautona Group Ip Holding Company, L.L.C. Iron chelating compounds for treating aesthetic skin conditions
WO2021155254A1 (en) 2020-01-31 2021-08-05 Nanocopoeia, Llc Amorphous nilotinib microparticles and uses thereof
WO2021222739A1 (en) 2020-04-30 2021-11-04 Nanocopoeia, Llc Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib
CN112870361A (zh) * 2021-01-28 2021-06-01 重庆医科大学 铁死亡抑制剂在制备预防或治疗铁过载导致的骨质疏松或骨丢失的药物中的应用
CN116203161A (zh) * 2022-05-30 2023-06-02 上海奥科达医药科技股份有限公司 地拉罗司颗粒剂中相关杂质的检测方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0009056D0 (en) * 2000-04-12 2000-05-31 Nestle Sa Composition comprising free amino acids
RU2008119410A (ru) * 2005-10-19 2009-11-27 Новартис АГ (CH) Диспергируемые таблетки, включающие деферасирокс
US8486423B2 (en) 2007-08-21 2013-07-16 Board Of Regents, The University Of Texas System Thermo-kinetic mixing for pharmaceutical applications
WO2009067557A1 (en) * 2007-11-19 2009-05-28 Teva Pharmaceutical Industries Ltd. Deferasirox pharmaceutical compositions
WO2009130604A2 (en) * 2008-04-21 2009-10-29 Actavis Group Ptc Ehf Solid state forms of deferasirox salts and process for the preparation thereof
WO2011070560A1 (en) 2009-12-07 2011-06-16 Mapi Pharma Hk Limited Processes for the preparation of deferasirox, and deferasirox polymorphs
US8703203B2 (en) 2010-07-08 2014-04-22 Ratiopharm Gmbh Oral dosage form of deferasirox
WO2012025935A2 (en) * 2010-08-25 2012-03-01 Ramamohan Rao Davuluri A process for the preparation of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one and its use for preparation of 4-[3, 5-bis (2-hydroxyphenyl)-1h-1, 2, 4-triazol-1-yl] benzoic acid
EP2621471A2 (en) * 2010-10-01 2013-08-07 Cipla Limited Pharmaceutical composition comprising deferasirox
WO2012116238A1 (en) * 2011-02-23 2012-08-30 Dispersol Technologies, Llc PHARMACEUTICAL FORMULATIONS OF ACETYL-11-KETO-β-BOSWELLIC ACID, DIINDOLYLMETHANE, AND CURCUMIN FOR PHARMACEUTICAL APPLICATIONS
TWI625136B (zh) 2013-03-08 2018-06-01 諾華公司 祛鐵斯若(deferasirox)之口服配方
MX2015015553A (es) 2013-05-10 2016-06-17 Cipla Ltd Composicion farmceutica de dosis baja.

Also Published As

Publication number Publication date
WO2016205658A1 (en) 2016-12-22
EP3310354A4 (en) 2018-12-12
IL256322A (en) 2018-02-28
IL256322B (en) 2022-03-01
MA43271A (fr) 2018-09-26
US20170296514A1 (en) 2017-10-19
CN107847490A (zh) 2018-03-27
AU2024202528A1 (en) 2024-05-09
US11878005B2 (en) 2024-01-23
JP2018517734A (ja) 2018-07-05
AU2021277731A1 (en) 2021-12-23
AU2016280280A1 (en) 2018-01-04
CA2989145A1 (en) 2016-12-22
AU2016280280B2 (en) 2021-09-02
US10265301B2 (en) 2019-04-23
US20240091201A1 (en) 2024-03-21
US20170027911A1 (en) 2017-02-02
EP3310354A1 (en) 2018-04-25
US20190167643A1 (en) 2019-06-06
US10258608B2 (en) 2019-04-16
AU2021277731B2 (en) 2024-04-11

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