HK1254608A1 - 改良的地拉羅司製劑及其製備方法 - Google Patents
改良的地拉羅司製劑及其製備方法Info
- Publication number
- HK1254608A1 HK1254608A1 HK18113574.7A HK18113574A HK1254608A1 HK 1254608 A1 HK1254608 A1 HK 1254608A1 HK 18113574 A HK18113574 A HK 18113574A HK 1254608 A1 HK1254608 A1 HK 1254608A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- deferasirox
- making
- methods
- same
- improved formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562180998P | 2015-06-17 | 2015-06-17 | |
| PCT/US2016/038089 WO2016205658A1 (en) | 2015-06-17 | 2016-06-17 | Improved formulations of deferasirox and methods of making the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1254608A1 true HK1254608A1 (zh) | 2019-07-26 |
Family
ID=57546755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18113574.7A HK1254608A1 (zh) | 2015-06-17 | 2018-10-23 | 改良的地拉羅司製劑及其製備方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US10265301B2 (zh) |
| EP (1) | EP3310354A4 (zh) |
| JP (1) | JP2018517734A (zh) |
| CN (1) | CN107847490A (zh) |
| AU (3) | AU2016280280B2 (zh) |
| CA (1) | CA2989145A1 (zh) |
| HK (1) | HK1254608A1 (zh) |
| IL (1) | IL256322B (zh) |
| MA (1) | MA43271A (zh) |
| WO (1) | WO2016205658A1 (zh) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2610351B1 (en) | 2007-12-05 | 2015-07-08 | Complete Genomics, Inc. | Efficient base determination in sequencing reactions |
| US10098857B2 (en) | 2008-10-10 | 2018-10-16 | The Board Of Trustees Of The Leland Stanford Junior University | Topical and transdermal delivery of HIF-1 modulators to prevent and treat chronic wounds |
| CA2765427A1 (en) | 2009-06-15 | 2010-12-23 | Complete Genomics, Inc. | Methods and compositions for long fragment read sequencing |
| US10837879B2 (en) | 2011-11-02 | 2020-11-17 | Complete Genomics, Inc. | Treatment for stabilizing nucleic acid arrays |
| CZ2017255A3 (cs) * | 2017-05-04 | 2018-11-14 | Zentiva, K.S. | Filmem potažené tablety Deferasiroxu |
| US11331288B2 (en) | 2017-09-14 | 2022-05-17 | The Board Of Trustees Of The Leland Stanford Junior University | Conditioning irradiated tissue for increasing vascularity |
| WO2019094688A1 (en) * | 2017-11-10 | 2019-05-16 | Dispersol Technologies, Llc | Improved drug formulations |
| CA3113175A1 (en) * | 2018-09-20 | 2020-03-26 | Tautona Group Ip Holding Company, L.L.C. | Iron chelating compounds for treating aesthetic skin conditions |
| WO2021155254A1 (en) | 2020-01-31 | 2021-08-05 | Nanocopoeia, Llc | Amorphous nilotinib microparticles and uses thereof |
| WO2021222739A1 (en) | 2020-04-30 | 2021-11-04 | Nanocopoeia, Llc | Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib |
| CN112870361A (zh) * | 2021-01-28 | 2021-06-01 | 重庆医科大学 | 铁死亡抑制剂在制备预防或治疗铁过载导致的骨质疏松或骨丢失的药物中的应用 |
| CN116203161A (zh) * | 2022-05-30 | 2023-06-02 | 上海奥科达医药科技股份有限公司 | 地拉罗司颗粒剂中相关杂质的检测方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0009056D0 (en) * | 2000-04-12 | 2000-05-31 | Nestle Sa | Composition comprising free amino acids |
| RU2008119410A (ru) * | 2005-10-19 | 2009-11-27 | Новартис АГ (CH) | Диспергируемые таблетки, включающие деферасирокс |
| US8486423B2 (en) | 2007-08-21 | 2013-07-16 | Board Of Regents, The University Of Texas System | Thermo-kinetic mixing for pharmaceutical applications |
| WO2009067557A1 (en) * | 2007-11-19 | 2009-05-28 | Teva Pharmaceutical Industries Ltd. | Deferasirox pharmaceutical compositions |
| WO2009130604A2 (en) * | 2008-04-21 | 2009-10-29 | Actavis Group Ptc Ehf | Solid state forms of deferasirox salts and process for the preparation thereof |
| WO2011070560A1 (en) | 2009-12-07 | 2011-06-16 | Mapi Pharma Hk Limited | Processes for the preparation of deferasirox, and deferasirox polymorphs |
| US8703203B2 (en) | 2010-07-08 | 2014-04-22 | Ratiopharm Gmbh | Oral dosage form of deferasirox |
| WO2012025935A2 (en) * | 2010-08-25 | 2012-03-01 | Ramamohan Rao Davuluri | A process for the preparation of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one and its use for preparation of 4-[3, 5-bis (2-hydroxyphenyl)-1h-1, 2, 4-triazol-1-yl] benzoic acid |
| EP2621471A2 (en) * | 2010-10-01 | 2013-08-07 | Cipla Limited | Pharmaceutical composition comprising deferasirox |
| WO2012116238A1 (en) * | 2011-02-23 | 2012-08-30 | Dispersol Technologies, Llc | PHARMACEUTICAL FORMULATIONS OF ACETYL-11-KETO-β-BOSWELLIC ACID, DIINDOLYLMETHANE, AND CURCUMIN FOR PHARMACEUTICAL APPLICATIONS |
| TWI625136B (zh) | 2013-03-08 | 2018-06-01 | 諾華公司 | 祛鐵斯若（ｄｅｆｅｒａｓｉｒｏｘ）之口服配方 |
| MX2015015553A (es) | 2013-05-10 | 2016-06-17 | Cipla Ltd | Composicion farmceutica de dosis baja. |
-
2016
- 2016-06-17 EP EP16812529.2A patent/EP3310354A4/en active Pending
- 2016-06-17 AU AU2016280280A patent/AU2016280280B2/en active Active
- 2016-06-17 CA CA2989145A patent/CA2989145A1/en active Pending
- 2016-06-17 CN CN201680042313.0A patent/CN107847490A/zh active Pending
- 2016-06-17 MA MA043271A patent/MA43271A/fr unknown
- 2016-06-17 WO PCT/US2016/038089 patent/WO2016205658A1/en active Application Filing
- 2016-06-17 JP JP2017565048A patent/JP2018517734A/ja active Pending
- 2016-06-17 US US15/185,888 patent/US10265301B2/en active Active
-
2017
- 2017-06-28 US US15/636,174 patent/US10258608B2/en active Active
- 2017-12-14 IL IL256322A patent/IL256322B/en unknown
-
2018
- 2018-10-23 HK HK18113574.7A patent/HK1254608A1/zh unknown
-
2019
- 2019-02-06 US US16/268,785 patent/US11878005B2/en active Active
-
2021
- 2021-12-02 AU AU2021277731A patent/AU2021277731B2/en active Active
-
2023
- 2023-11-24 US US18/518,819 patent/US20240091201A1/en active Pending
-
2024
- 2024-04-17 AU AU2024202528A patent/AU2024202528A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016205658A1 (en) | 2016-12-22 |
| EP3310354A4 (en) | 2018-12-12 |
| IL256322A (en) | 2018-02-28 |
| IL256322B (en) | 2022-03-01 |
| MA43271A (fr) | 2018-09-26 |
| US20170296514A1 (en) | 2017-10-19 |
| CN107847490A (zh) | 2018-03-27 |
| AU2024202528A1 (en) | 2024-05-09 |
| US11878005B2 (en) | 2024-01-23 |
| JP2018517734A (ja) | 2018-07-05 |
| AU2021277731A1 (en) | 2021-12-23 |
| AU2016280280A1 (en) | 2018-01-04 |
| CA2989145A1 (en) | 2016-12-22 |
| AU2016280280B2 (en) | 2021-09-02 |
| US10265301B2 (en) | 2019-04-23 |
| US20240091201A1 (en) | 2024-03-21 |
| US20170027911A1 (en) | 2017-02-02 |
| EP3310354A1 (en) | 2018-04-25 |
| US20190167643A1 (en) | 2019-06-06 |
| US10258608B2 (en) | 2019-04-16 |
| AU2021277731B2 (en) | 2024-04-11 |
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