HK1254608A1 - 改良的地拉罗司制剂及其制备方法 - Google Patents
改良的地拉罗司制剂及其制备方法 Download PDFInfo
- Publication number
- HK1254608A1 HK1254608A1 HK18113574.7A HK18113574A HK1254608A1 HK 1254608 A1 HK1254608 A1 HK 1254608A1 HK 18113574 A HK18113574 A HK 18113574A HK 1254608 A1 HK1254608 A1 HK 1254608A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methods
- same
- deferasirox
- making
- improved formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562180998P | 2015-06-17 | 2015-06-17 | |
| US62/180,998 | 2015-06-17 | ||
| PCT/US2016/038089 WO2016205658A1 (en) | 2015-06-17 | 2016-06-17 | Improved formulations of deferasirox and methods of making the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1254608A1 true HK1254608A1 (zh) | 2019-07-26 |
Family
ID=57546755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18113574.7A HK1254608A1 (zh) | 2015-06-17 | 2016-06-17 | 改良的地拉罗司制剂及其制备方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US10265301B2 (https=) |
| EP (1) | EP3310354B1 (https=) |
| JP (1) | JP2018517734A (https=) |
| CN (1) | CN107847490A (https=) |
| AU (3) | AU2016280280B2 (https=) |
| CA (1) | CA2989145C (https=) |
| HK (1) | HK1254608A1 (https=) |
| IL (1) | IL256322B (https=) |
| MA (1) | MA43271A (https=) |
| WO (1) | WO2016205658A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103290106B (zh) | 2007-12-05 | 2015-07-29 | 考利达基因组股份有限公司 | 测序反应中碱基的有效确定 |
| US10098857B2 (en) | 2008-10-10 | 2018-10-16 | The Board Of Trustees Of The Leland Stanford Junior University | Topical and transdermal delivery of HIF-1 modulators to prevent and treat chronic wounds |
| DK2443236T3 (en) | 2009-06-15 | 2015-08-17 | Complete Genomics Inc | Methods and compositions for sequencing by long fragment reading |
| US10837879B2 (en) | 2011-11-02 | 2020-11-17 | Complete Genomics, Inc. | Treatment for stabilizing nucleic acid arrays |
| CZ2017255A3 (cs) * | 2017-05-04 | 2018-11-14 | Zentiva, K.S. | Filmem potažené tablety Deferasiroxu |
| US11331288B2 (en) | 2017-09-14 | 2022-05-17 | The Board Of Trustees Of The Leland Stanford Junior University | Conditioning irradiated tissue for increasing vascularity |
| CN111511365A (zh) * | 2017-11-10 | 2020-08-07 | 分散技术有限责任公司 | 改进的药物制剂 |
| US20210315789A1 (en) * | 2018-09-20 | 2021-10-14 | Tautona Group Ip Holding Company, L.L.C. | Iron chelators for treating aesthetic skin conditions |
| CA3168680A1 (en) | 2020-01-31 | 2021-08-05 | Nanocopoeia, Llc | Amorphous nilotinib microparticles and uses thereof |
| WO2021222739A1 (en) | 2020-04-30 | 2021-11-04 | Nanocopoeia, Llc | Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib |
| CN112870361A (zh) * | 2021-01-28 | 2021-06-01 | 重庆医科大学 | 铁死亡抑制剂在制备预防或治疗铁过载导致的骨质疏松或骨丢失的药物中的应用 |
| CN116203161A (zh) * | 2022-05-30 | 2023-06-02 | 上海奥科达医药科技股份有限公司 | 地拉罗司颗粒剂中相关杂质的检测方法 |
| WO2025151876A1 (en) * | 2024-01-11 | 2025-07-17 | Minneamrita Therapeutics Llc | Triptolide formulations |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0009056D0 (en) * | 2000-04-12 | 2000-05-31 | Nestle Sa | Composition comprising free amino acids |
| EP1940360A1 (en) * | 2005-10-19 | 2008-07-09 | Novartis AG | Dispersible tablets comprising deferasirox |
| CA3076115C (en) | 2007-08-21 | 2022-06-28 | Board Of Regents, The University Of Texas System | Thermo-kinetic mixing for pharmaceutical applications |
| EP2062572A1 (en) * | 2007-11-19 | 2009-05-27 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical compositions |
| US20110097413A1 (en) * | 2008-04-21 | 2011-04-28 | Actavis Group Ptc Ehf | Solid state forms of deferasirox salts and process for the preparation thereof |
| WO2011070560A1 (en) | 2009-12-07 | 2011-06-16 | Mapi Pharma Hk Limited | Processes for the preparation of deferasirox, and deferasirox polymorphs |
| US8703203B2 (en) | 2010-07-08 | 2014-04-22 | Ratiopharm Gmbh | Oral dosage form of deferasirox |
| WO2012025935A2 (en) * | 2010-08-25 | 2012-03-01 | Ramamohan Rao Davuluri | A process for the preparation of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one and its use for preparation of 4-[3, 5-bis (2-hydroxyphenyl)-1h-1, 2, 4-triazol-1-yl] benzoic acid |
| MY165826A (en) | 2010-10-01 | 2018-05-17 | Cipla Ltd | Pharmaceutical composition |
| US20140039031A1 (en) * | 2011-02-23 | 2014-02-06 | Dispersol Technologies. LLC | Pharmaceutical formulations of acetyl-11-keto-b-boswellic acid, diindolylmethane, and curcumin for pharmaceutical applications |
| ME03297B (me) | 2013-03-08 | 2019-07-20 | Novartis Ag | Oralne formulacije deferasiroksa |
| HK1215191A1 (zh) * | 2013-05-10 | 2016-08-19 | Cipla Limited | 低剂量医药组合物 |
-
2016
- 2016-06-17 CN CN201680042313.0A patent/CN107847490A/zh active Pending
- 2016-06-17 AU AU2016280280A patent/AU2016280280B2/en active Active
- 2016-06-17 WO PCT/US2016/038089 patent/WO2016205658A1/en not_active Ceased
- 2016-06-17 US US15/185,888 patent/US10265301B2/en active Active
- 2016-06-17 HK HK18113574.7A patent/HK1254608A1/zh unknown
- 2016-06-17 MA MA043271A patent/MA43271A/fr unknown
- 2016-06-17 EP EP16812529.2A patent/EP3310354B1/en active Active
- 2016-06-17 JP JP2017565048A patent/JP2018517734A/ja active Pending
- 2016-06-17 CA CA2989145A patent/CA2989145C/en active Active
-
2017
- 2017-06-28 US US15/636,174 patent/US10258608B2/en active Active
- 2017-12-14 IL IL256322A patent/IL256322B/en unknown
-
2019
- 2019-02-06 US US16/268,785 patent/US11878005B2/en active Active
-
2021
- 2021-12-02 AU AU2021277731A patent/AU2021277731B2/en active Active
-
2023
- 2023-11-24 US US18/518,819 patent/US20240091201A1/en active Pending
-
2024
- 2024-04-17 AU AU2024202528A patent/AU2024202528B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2016280280B2 (en) | 2021-09-02 |
| JP2018517734A (ja) | 2018-07-05 |
| CN107847490A (zh) | 2018-03-27 |
| AU2021277731A1 (en) | 2021-12-23 |
| US20170296514A1 (en) | 2017-10-19 |
| US10258608B2 (en) | 2019-04-16 |
| IL256322B (en) | 2022-03-01 |
| AU2024202528A1 (en) | 2024-05-09 |
| US20240091201A1 (en) | 2024-03-21 |
| CA2989145C (en) | 2024-10-29 |
| EP3310354B1 (en) | 2026-02-25 |
| US20190167643A1 (en) | 2019-06-06 |
| AU2024202528B2 (en) | 2026-01-08 |
| US20170027911A1 (en) | 2017-02-02 |
| US11878005B2 (en) | 2024-01-23 |
| EP3310354A1 (en) | 2018-04-25 |
| AU2016280280A1 (en) | 2018-01-04 |
| US10265301B2 (en) | 2019-04-23 |
| CA2989145A1 (en) | 2016-12-22 |
| EP3310354A4 (en) | 2018-12-12 |
| IL256322A (en) | 2018-02-28 |
| MA43271A (fr) | 2018-09-26 |
| AU2021277731B2 (en) | 2024-04-11 |
| EP3310354C0 (en) | 2026-02-25 |
| WO2016205658A1 (en) | 2016-12-22 |
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