MA42137A - Anticorps vhb anti-pre-s1 - Google Patents

Anticorps vhb anti-pre-s1

Info

Publication number
MA42137A
MA42137A MA042137A MA42137A MA42137A MA 42137 A MA42137 A MA 42137A MA 042137 A MA042137 A MA 042137A MA 42137 A MA42137 A MA 42137A MA 42137 A MA42137 A MA 42137A
Authority
MA
Morocco
Prior art keywords
vhb
antibody
vhb antibody
Prior art date
Application number
MA042137A
Other languages
English (en)
French (fr)
Inventor
Dan Li
Wenhui Li
Jianhua Sui
Original Assignee
Huahui Health Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huahui Health Ltd filed Critical Huahui Health Ltd
Publication of MA42137A publication Critical patent/MA42137A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/082Hepadnaviridae, e.g. hepatitis B virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MA042137A 2015-05-22 2016-05-23 Anticorps vhb anti-pre-s1 MA42137A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2015079534 2015-05-22

Publications (1)

Publication Number Publication Date
MA42137A true MA42137A (fr) 2021-04-07

Family

ID=57392535

Family Applications (1)

Application Number Title Priority Date Filing Date
MA042137A MA42137A (fr) 2015-05-22 2016-05-23 Anticorps vhb anti-pre-s1

Country Status (10)

Country Link
US (3) US20180094047A1 (enExample)
EP (2) EP3298038B1 (enExample)
JP (2) JP6820278B2 (enExample)
KR (1) KR102770671B1 (enExample)
CN (3) CN107614525B (enExample)
ES (1) ES2896275T3 (enExample)
HK (1) HK1243429A1 (enExample)
MA (1) MA42137A (enExample)
RU (1) RU2739955C2 (enExample)
WO (1) WO2016188386A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6820278B2 (ja) 2015-05-22 2021-01-27 フアフイ ヘルス リミテッドHuahui Health Ltd. 抗Pre−S1 HBV抗体
JP7466459B2 (ja) 2018-04-17 2024-04-12 セルデックス セラピューティクス インコーポレイテッド 抗cd27および抗pd-l1抗体ならびに二重特異性構築物
JP7454855B2 (ja) * 2018-12-21 2024-03-25 国立大学法人広島大学 抗preS1抗体およびその用途
JP2022542035A (ja) * 2019-07-20 2022-09-29 フアフイ ヘルス リミテッド 抗pre-s1 hbv抗体を用いるhbv感染症の治療方法
WO2022265264A1 (ko) * 2021-06-15 2022-12-22 에이피트바이오 주식회사 B형 간염바이러스 pres1항원의 간세포 수용체 결합부위에 특이적으로 결합하는 인간 항체 및 이의 용도
US20240391979A1 (en) * 2021-09-13 2024-11-28 Achelois Biopharma, Inc. Hepatitis b virus antivirus (hbv-antivirus) compositions and methods of use
CN116568808A (zh) * 2021-10-19 2023-08-08 北京三诺佳邑生物技术有限责任公司 特异性结合乙型肝炎病毒表面抗原pre-S1的抗体及其应用
CN114685663B (zh) * 2022-04-07 2023-09-08 西南大学 一种抗胆固醇依赖性细胞溶素的抗体及其应用
CN117304308A (zh) * 2022-06-20 2023-12-29 华辉安健(北京)生物科技有限公司 抗乙型肝炎病毒的抗体及其制备和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
CA2041772A1 (en) * 1990-05-11 1991-11-12 Larry T. Mimms Monoclonal antibodies to pres2 and pres1 polypeptide of the hepatitis b viral envelope
JP2002502222A (ja) * 1992-11-06 2002-01-22 ノバーティス アクチエンゲゼルシャフト B型肝炎表面抗原に対して活性なヒトモノクローナル抗体の生産
KR100345463B1 (ko) * 1998-11-19 2003-01-08 주)녹십자 B형간염바이러스의표면항원프리-s1에대한인간화항체및이의제조방법
CN1216914C (zh) * 2000-05-17 2005-08-31 韩国科学技术研究院 对hbv表面抗原pre-s1具有特异性的人源化抗体
KR100423614B1 (ko) * 2001-05-16 2004-03-22 주식회사유한양행 비형간염바이러스의 에스-표면항원을 인식하는단일클론항체의 가변영역 및 이를 코딩하는 유전자
EP1281761A1 (en) * 2001-07-27 2003-02-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Hepatitis B virus pre-S1 derived synthetic polypeptides and their use thereof.
US7601351B1 (en) * 2002-06-26 2009-10-13 Human Genome Sciences, Inc. Antibodies against protective antigen
CN1733798B (zh) * 2005-08-12 2012-07-04 上海贺普生物科技有限公司 乙型肝炎病毒表面l蛋白相关肽
WO2011045079A1 (en) * 2009-10-15 2011-04-21 Intercell Ag Hepatitis b virus specific human antibodies
WO2013159243A1 (en) 2012-04-25 2013-10-31 National Institute Of Biological Sciences, Beijing Compositions and uses of functional receptor for hbv/hdv virus
JP6820278B2 (ja) 2015-05-22 2021-01-27 フアフイ ヘルス リミテッドHuahui Health Ltd. 抗Pre−S1 HBV抗体

Also Published As

Publication number Publication date
US20200109186A1 (en) 2020-04-09
US20180148496A1 (en) 2018-05-31
CN117247944A (zh) 2023-12-19
WO2016188386A1 (en) 2016-12-01
US20180094047A1 (en) 2018-04-05
JP2020171311A (ja) 2020-10-22
HK1243429A1 (zh) 2018-07-13
KR102770671B1 (ko) 2025-02-24
CN107614525A (zh) 2018-01-19
RU2739955C2 (ru) 2020-12-30
RU2017145085A (ru) 2019-06-24
US20220275060A9 (en) 2022-09-01
US11485774B2 (en) 2022-11-01
EP3978521A1 (en) 2022-04-06
KR20180009780A (ko) 2018-01-29
ES2896275T3 (es) 2022-02-24
JP7304320B2 (ja) 2023-07-06
CN113527470B (zh) 2023-08-25
EP3298038B1 (en) 2021-08-04
EP3298038A4 (en) 2019-04-24
JP2018519804A (ja) 2018-07-26
CN107614525B (zh) 2021-07-06
CN113527470A (zh) 2021-10-22
US10544205B2 (en) 2020-01-28
RU2017145085A3 (enExample) 2020-01-23
JP6820278B2 (ja) 2021-01-27
EP3298038A1 (en) 2018-03-28

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