MA39550B1 - Système d'expression génique - Google Patents
Système d'expression géniqueInfo
- Publication number
- MA39550B1 MA39550B1 MA39550A MA39550A MA39550B1 MA 39550 B1 MA39550 B1 MA 39550B1 MA 39550 A MA39550 A MA 39550A MA 39550 A MA39550 A MA 39550A MA 39550 B1 MA39550 B1 MA 39550B1
- Authority
- MA
- Morocco
- Prior art keywords
- gene expression
- insect
- expression system
- lethal
- conditional gene
- Prior art date
Links
- 230000014509 gene expression Effects 0.000 title abstract 3
- 241000238631 Hexapoda Species 0.000 abstract 3
- 231100000518 lethal Toxicity 0.000 abstract 2
- 230000001665 lethal effect Effects 0.000 abstract 2
- 231100000225 lethality Toxicity 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
- A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
- A01K67/0337—Genetically modified Arthropods
- A01K67/0339—Genetically modified insects, e.g. Drosophila melanogaster, medfly
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/15—Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination, e.g. obtained by cross-breeding
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
- A01K2217/203—Animal model comprising inducible/conditional expression system, e.g. hormones, tet
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
- A01K2217/206—Animal model comprising tissue-specific expression system, e.g. tissue specific expression of transgene, of Cre recombinase
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/30—Animal model comprising expression system for selective cell killing, e.g. toxins, enzyme dependent prodrug therapy using ganciclovir
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/70—Invertebrates
- A01K2227/706—Insects, e.g. Drosophila melanogaster, medfly
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/90—Vectors containing a transposable element
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/005—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB
- C12N2830/006—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB tet repressible
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/007—Vectors comprising a special translation-regulating system cell or tissue specific
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/75—Vectors comprising a special translation-regulating system from invertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2999/00—Further aspects of viruses or vectors not covered by groups C12N2710/00 - C12N2796/00 or C12N2800/00
- C12N2999/007—Technological advancements, e.g. new system for producing known virus, cre-lox system for production of transgenic animals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Environmental Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La présente invention concerne deux ou plus de deux systèmes d'expression génique conditionnels dominants létaux qui permettent d'obtenir de hauts niveaux de pénétration chez des insectes. La létalité est induite à un stade précoce de développement et le risque de résistance biochimique est réduit par comparaison avec un système unique d'expression génique conditionnel dominant létal d'insecte. L'invention est utile pour la lutte contre des populations d'insectes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1410023.4A GB2526867A (en) | 2014-06-05 | 2014-06-05 | Gene expression system |
PCT/GB2015/051633 WO2015185933A1 (fr) | 2014-06-05 | 2015-06-04 | Système d'expression génique |
Publications (1)
Publication Number | Publication Date |
---|---|
MA39550B1 true MA39550B1 (fr) | 2018-11-30 |
Family
ID=51214800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA39550A MA39550B1 (fr) | 2014-06-05 | 2015-06-04 | Système d'expression génique |
Country Status (18)
Country | Link |
---|---|
US (3) | US20170188559A1 (fr) |
EP (1) | EP3152311B1 (fr) |
KR (1) | KR20170012551A (fr) |
CN (1) | CN107075529A (fr) |
AP (1) | AP2016009600A0 (fr) |
AR (1) | AR100766A1 (fr) |
AU (1) | AU2015270238B2 (fr) |
BR (1) | BR112016028197B1 (fr) |
CA (1) | CA2950851A1 (fr) |
CL (1) | CL2016003140A1 (fr) |
CR (1) | CR20160594A (fr) |
GB (1) | GB2526867A (fr) |
IL (1) | IL249254B (fr) |
MA (1) | MA39550B1 (fr) |
MX (1) | MX2016016029A (fr) |
PH (1) | PH12016502381A1 (fr) |
RU (1) | RU2016151395A (fr) |
WO (1) | WO2015185933A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2526867A (en) | 2014-06-05 | 2015-12-09 | Oxitec Ltd | Gene expression system |
GB2540786A (en) * | 2015-07-28 | 2017-02-01 | Glaxosmithkline Ip Dev Ltd | Codon optimised tet repressor proteins |
US11827876B2 (en) | 2016-08-12 | 2023-11-28 | Oxitec Ltd. | Self-limiting, sex-specific gene and methods of using |
CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
US11968963B2 (en) | 2018-04-05 | 2024-04-30 | Vanderbilt University | Male arthropod killing factors and methods of use thereof |
MA52650A1 (fr) | 2018-08-14 | 2021-12-31 | Oxitec Ltd | Arthropodes mâles stériles à sélection automatique |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
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US5180873A (en) | 1985-04-16 | 1993-01-19 | Dna Plant Technology Corporation | Transformation of plants to introduce closely linked markers |
GB8901677D0 (en) | 1989-01-26 | 1989-03-15 | Ici Plc | Hybrid seed production |
US5643776A (en) | 1988-11-01 | 1997-07-01 | The Regents Of The University Of California | Insect diagnostic and control compositions |
US5354844A (en) | 1989-03-16 | 1994-10-11 | Boehringer Ingelheim International Gmbh | Protein-polycation conjugates |
US5254801A (en) | 1990-12-03 | 1993-10-19 | Monsanto Company | Heterologous dominant conditional lethal gene which is a phosphonate monoester hydrolase and use thereof in plants |
GB9216151D0 (en) | 1992-07-29 | 1992-09-09 | Ici Plc | Containment of plant germplasm |
US6225121B1 (en) | 1992-09-14 | 2001-05-01 | Institute Of Molecular Biology And Biotechnology/Forth | Eukaryotic transposable element |
GB9313975D0 (en) | 1993-07-06 | 1993-08-18 | Sandoz Ltd | Improvements in or relating to organic compounds |
EG23907A (en) | 1994-08-01 | 2007-12-30 | Delta & Pine Land Co | Control of plant gene expression |
US5633447A (en) | 1994-08-25 | 1997-05-27 | Mycogen Plant Science, Inc. | Plant tissue comprising a subgenomic promoter |
US5753434A (en) | 1995-02-10 | 1998-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for altering sexual behavior |
US5851796A (en) | 1995-06-07 | 1998-12-22 | Yale University | Autoregulatory tetracycline-regulated system for inducible gene expression in eucaryotes |
FR2737731B1 (fr) | 1995-08-07 | 1997-10-10 | Pasteur Institut | Sequence de retroelements naturels ou synthetiques ayant pour fonction de permettre l'insertion de sequences nucleotidiques dans une cellule eucaryote |
AUPN816196A0 (en) | 1996-02-19 | 1996-03-14 | Forbio Research Pty Ltd | Regulation of eukaryotic gene expression |
US5773697A (en) | 1996-04-23 | 1998-06-30 | Pioneer Hi-Bred International, Inc. | Genetic constructs and methods for producing fruits with very little or diminished seed |
EP0920521A1 (fr) | 1996-08-26 | 1999-06-09 | Genencor International, Inc. | IDENTIFICATION ET CLONAGE D'UN TRANSPOSON MOBILE ISSU D'$i(ASPERGILLUS) |
AU722221B2 (en) | 1996-10-01 | 2000-07-27 | American Cyanamid Company | Biological insect control agents expressing insect-specific mite toxin genes, methods and compositions |
US7135608B1 (en) | 1997-08-28 | 2006-11-14 | The Salk Institute For Biological Studies | Site-specific recombination in eukaryotes and constructs useful therefor |
US6338040B1 (en) | 1999-02-12 | 2002-01-08 | Agren, Inc. | Method for delaying the development in pest species of resistance to control techniques, using insurance to encourage correct uses of refuges |
EP2395094A3 (fr) | 1999-06-01 | 2012-04-18 | The University of Utah Research Foundation | Procédé de mutagénèse par transposon dans le nématode caenorhabditis elegans |
GB2355459B (en) | 1999-11-29 | 2001-09-26 | Isis Innovation | A dominant conditional lethal genetic system |
JP2003521941A (ja) | 2000-02-11 | 2003-07-22 | クイーンメリー アンド ウエストフィールド カレッジ | ベクター |
US20030150007A1 (en) | 2000-03-21 | 2003-08-07 | Charalambos Savakis | Method of generating transgenic organisms using transposons |
AU2001265187A1 (en) | 2000-05-30 | 2001-12-11 | Baylor College Of Medicine | Chimeric viral vectors for gene therapy |
US6962810B2 (en) | 2000-10-31 | 2005-11-08 | University Of Notre Dame Du Lac | Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac |
EP1339863A2 (fr) | 2000-12-05 | 2003-09-03 | Wisconsin Alumni Research Foundation | Procedes de transposition double destines a la manipulation d'acides nucleiques |
ITRM20010120A1 (it) | 2001-03-08 | 2002-09-08 | Univ Napoli Federico Ii | Gene cctra come strumento per produrre progenie di soli maschi nella mosca mediterranea ceratitis capitata. |
FR2825579B1 (fr) | 2001-06-11 | 2004-07-23 | Rhobio | Methode d'obtention de plante monocotyledone contenant un gene d'interet sans sequence auxiliaire etrangere |
DE10251918A1 (de) | 2002-11-08 | 2004-05-19 | Horn, Carsten, Dipl.-Biochem. Dr. | Systeme zur Erzeugung stabiler genomischer Transgen-Insertionen |
GB2402675B (en) | 2003-05-12 | 2008-02-20 | Oxitec Ltd | Resistance dilution |
ATE406450T1 (de) | 2003-06-10 | 2008-09-15 | Ca Nat Research Council | Ein coumermycin/novobiocin-reguliertes genexpressionsystem |
GB2403475B (en) | 2003-07-01 | 2008-02-06 | Oxitec Ltd | Stable integrands |
GB2404382B (en) | 2003-07-28 | 2008-01-30 | Oxitec Ltd | Pest control |
CA2559280A1 (fr) | 2004-03-15 | 2005-09-29 | Biogen Idec Ma Inc. | Methodes et constructions permettant d'exprimer des multimeres polypeptidiques dans des cellules eucaryotes au moyen de l'epissage alternatif |
US7563601B1 (en) | 2005-06-01 | 2009-07-21 | City Of Hope | Artificial riboswitch for controlling pre-mRNA splicing |
MX2008010285A (es) | 2006-02-10 | 2009-01-16 | Oxitec Ltd | Sistema de expresion genetica usando un empalme alternativo en insectos. |
GB2443186A (en) | 2006-10-25 | 2008-04-30 | Oxitec Ltd | Expression system for mediating alternative splicing |
JP2008067678A (ja) | 2006-09-15 | 2008-03-27 | Kyushu Institute Of Technology | 昆虫の減数分裂期における染色体標的組換え誘導方法 |
CN101688246B (zh) | 2007-04-26 | 2013-09-25 | 默沙东公司 | 用于昆虫细胞的合成的表达载体 |
EP2183277A1 (fr) | 2007-07-30 | 2010-05-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Peptides sexuels resistant a une degradation proteolytique et leur utilisation dans la lutte biologique contre les insectes |
WO2009115569A1 (fr) | 2008-03-20 | 2009-09-24 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts | Système de létalité spécifique au stade de développement pour la régulation d’une population d’insectes |
KR102261586B1 (ko) * | 2008-06-27 | 2021-06-08 | 메뤼스 엔.페. | 항체 생산 비-인간 포유동물 |
WO2011082310A2 (fr) | 2009-12-30 | 2011-07-07 | Pioneer Hi-Bred International, Inc. | Procédés et compositions pour la modification ciblée de polynucléotides |
GB2500113A (en) | 2012-03-05 | 2013-09-11 | Oxitec Ltd | Arthropod male germline gene expression system |
GB201303932D0 (en) | 2013-03-05 | 2013-04-17 | Oxitec Ltd | Muscle actin promoter |
CN104046648A (zh) * | 2013-03-15 | 2014-09-17 | 中国人民解放军军事医学科学院生物工程研究所 | 大肠杆菌-链霉菌穿梭型bac载体及其构建方法 |
GB2526867A (en) | 2014-06-05 | 2015-12-09 | Oxitec Ltd | Gene expression system |
US11827876B2 (en) | 2016-08-12 | 2023-11-28 | Oxitec Ltd. | Self-limiting, sex-specific gene and methods of using |
AR117409A1 (es) | 2018-03-29 | 2021-08-04 | Oxitec Ltd | Noctuidas autolimitantes |
MA52650A1 (fr) | 2018-08-14 | 2021-12-31 | Oxitec Ltd | Arthropodes mâles stériles à sélection automatique |
-
2014
- 2014-06-05 GB GB1410023.4A patent/GB2526867A/en not_active Withdrawn
-
2015
- 2015-06-04 WO PCT/GB2015/051633 patent/WO2015185933A1/fr active Application Filing
- 2015-06-04 CR CR20160594A patent/CR20160594A/es unknown
- 2015-06-04 US US15/313,922 patent/US20170188559A1/en not_active Abandoned
- 2015-06-04 MA MA39550A patent/MA39550B1/fr unknown
- 2015-06-04 CA CA2950851A patent/CA2950851A1/fr not_active Abandoned
- 2015-06-04 CN CN201580038806.2A patent/CN107075529A/zh active Pending
- 2015-06-04 AU AU2015270238A patent/AU2015270238B2/en active Active
- 2015-06-04 KR KR1020177000229A patent/KR20170012551A/ko unknown
- 2015-06-04 MX MX2016016029A patent/MX2016016029A/es unknown
- 2015-06-04 AP AP2016009600A patent/AP2016009600A0/en unknown
- 2015-06-04 RU RU2016151395A patent/RU2016151395A/ru not_active Application Discontinuation
- 2015-06-04 EP EP15750085.1A patent/EP3152311B1/fr active Active
- 2015-06-04 BR BR112016028197-7A patent/BR112016028197B1/pt active IP Right Grant
- 2015-06-05 AR ARP150101800A patent/AR100766A1/es unknown
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2016
- 2016-11-28 IL IL249254A patent/IL249254B/en active IP Right Grant
- 2016-11-29 PH PH12016502381A patent/PH12016502381A1/en unknown
- 2016-12-05 CL CL2016003140A patent/CL2016003140A1/es unknown
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2020
- 2020-08-19 US US16/997,416 patent/US11737436B2/en active Active
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2023
- 2023-07-14 US US18/353,012 patent/US20240016132A1/en active Pending
Also Published As
Publication number | Publication date |
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GB2526867A (en) | 2015-12-09 |
US20240016132A1 (en) | 2024-01-18 |
KR20170012551A (ko) | 2017-02-02 |
US20170188559A1 (en) | 2017-07-06 |
AU2015270238A1 (en) | 2016-12-15 |
BR112016028197B1 (pt) | 2023-09-26 |
PH12016502381A1 (en) | 2017-02-20 |
MX2016016029A (es) | 2017-07-11 |
IL249254A0 (en) | 2017-02-28 |
EP3152311A1 (fr) | 2017-04-12 |
WO2015185933A1 (fr) | 2015-12-10 |
IL249254B (en) | 2021-04-29 |
AU2015270238B2 (en) | 2021-12-09 |
US20210137083A1 (en) | 2021-05-13 |
CR20160594A (es) | 2017-02-21 |
AR100766A1 (es) | 2016-11-02 |
RU2016151395A (ru) | 2018-07-17 |
US11737436B2 (en) | 2023-08-29 |
CA2950851A1 (fr) | 2015-12-10 |
EP3152311B1 (fr) | 2019-08-28 |
AP2016009600A0 (en) | 2016-12-31 |
GB201410023D0 (en) | 2014-07-16 |
BR112016028197A2 (pt) | 2018-07-03 |
CL2016003140A1 (es) | 2017-10-20 |
CN107075529A (zh) | 2017-08-18 |
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