MA34548B1 - Formes solides d'un inhibiteur puissant du vhc - Google Patents

Formes solides d'un inhibiteur puissant du vhc

Info

Publication number
MA34548B1
MA34548B1 MA35773A MA35773A MA34548B1 MA 34548 B1 MA34548 B1 MA 34548B1 MA 35773 A MA35773 A MA 35773A MA 35773 A MA35773 A MA 35773A MA 34548 B1 MA34548 B1 MA 34548B1
Authority
MA
Morocco
Prior art keywords
powerful
solid forms
hcv inhibitor
hcv
inhibitor
Prior art date
Application number
MA35773A
Other languages
English (en)
Inventor
Rolf-Stefan Brickl
Shirlynn Chen
Jihchin Chung
Mayur Suryakant Dudhedia
Danping Li
Zhi-Hui Lu
Siddharthya Mujumdar
Chitra Telang
Richard Varsolona
Zeren Wang
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44759789&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA34548(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MA34548B1 publication Critical patent/MA34548B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Cette invention concerne de nouvelles formes de sels de sodium du composé (1) suivant et leurs méthodes de préparation, des compositions pharmaceutiques associées et leur utilisation dans le traitement d'une infection par le virus de l'hépatite C (VHC).
MA35773A 2010-09-30 2011-09-23 Formes solides d'un inhibiteur puissant du vhc MA34548B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38824210P 2010-09-30 2010-09-30
PCT/US2011/052869 WO2012044520A1 (fr) 2010-09-30 2011-09-23 Formes solides d'un inhibiteur puissant du vhc

Publications (1)

Publication Number Publication Date
MA34548B1 true MA34548B1 (fr) 2013-09-02

Family

ID=44759789

Family Applications (1)

Application Number Title Priority Date Filing Date
MA35773A MA34548B1 (fr) 2010-09-30 2011-09-23 Formes solides d'un inhibiteur puissant du vhc

Country Status (22)

Country Link
US (2) US8598183B2 (fr)
EP (1) EP2621921A1 (fr)
JP (1) JP2013543495A (fr)
KR (1) KR20130108326A (fr)
CN (1) CN103153987A (fr)
AP (1) AP2013006733A0 (fr)
AR (1) AR083256A1 (fr)
AU (1) AU2011307346A1 (fr)
BR (1) BR112013007700A2 (fr)
CA (1) CA2813179A1 (fr)
CL (1) CL2013000578A1 (fr)
CO (1) CO6700844A2 (fr)
EA (1) EA201300422A1 (fr)
EC (1) ECSP13012552A (fr)
MA (1) MA34548B1 (fr)
MX (1) MX2013003551A (fr)
PE (1) PE20131351A1 (fr)
PH (1) PH12013500558A1 (fr)
SG (1) SG188376A1 (fr)
TW (1) TW201307327A (fr)
UY (1) UY33632A (fr)
WO (1) WO2012044520A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013543495A (ja) * 2010-09-30 2013-12-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 強力なｈｃｖインヒビターの固体形体
WO2013083553A1 (fr) * 2011-12-06 2013-06-13 Sanofi Formes cristallines du [(s)-1-carbamoyl-2-(phénylpyrimidin-2-ylamino)éthyl]amide de l'acide 2-(2-méthylaminopyrimidin-4-yl)-1h-indole-5-carboxylique
US20130261134A1 (en) * 2012-03-30 2013-10-03 Boehringer Ingelheim International Gmbh Mesylate salt forms of a potent hcv inhibitor
WO2014138374A1 (fr) 2013-03-08 2014-09-12 Boehringer Ingelheim International Gmbh Polythérapie par voie orale pour le traitement d'une infection par le vhc chez une sous-population spécifique de patients

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0649651B1 (fr) 1993-09-28 2000-12-13 R.P. Scherer GmbH Procédé de production de capsules en gélatine molle
US5821242A (en) * 1996-06-06 1998-10-13 Eli Lilly And Company Anti-viral compounds
EP2335700A1 (fr) * 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Inhibiteurs de la polymerase du virus hepatitis C avec une structure heterobicylic
TWI368507B (en) 2004-02-20 2012-07-21 Boehringer Ingelheim Int Viral polymerase inhibitors
JP5036567B2 (ja) 2005-02-11 2012-09-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ２，３−ジ置換インドール類の製造方法
CN101384250A (zh) 2005-11-09 2009-03-11 诺瓦提斯公司 利用临时增塑剂制备药物组合物的方法
JP2013543495A (ja) * 2010-09-30 2013-12-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 強力なｈｃｖインヒビターの固体形体

Also Published As

Publication number Publication date
SG188376A1 (en) 2013-04-30
US20120122887A1 (en) 2012-05-17
CO6700844A2 (es) 2013-06-28
BR112013007700A2 (pt) 2019-09-24
ECSP13012552A (es) 2013-06-28
AU2011307346A1 (en) 2013-02-21
CA2813179A1 (fr) 2012-04-05
US8598183B2 (en) 2013-12-03
EA201300422A1 (ru) 2013-09-30
PH12013500558A1 (en) 2013-05-06
TW201307327A (zh) 2013-02-16
CN103153987A (zh) 2013-06-12
MX2013003551A (es) 2013-05-01
AP2013006733A0 (en) 2013-02-28
US20140057928A1 (en) 2014-02-27
AR083256A1 (es) 2013-02-13
PE20131351A1 (es) 2013-12-04
CL2013000578A1 (es) 2013-08-02
EP2621921A1 (fr) 2013-08-07
JP2013543495A (ja) 2013-12-05
WO2012044520A1 (fr) 2012-04-05
UY33632A (es) 2012-04-30
KR20130108326A (ko) 2013-10-02

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