LV13258B - Method for producing youthful-appearing, small-pored, and smooth skin - Google Patents
Method for producing youthful-appearing, small-pored, and smooth skin Download PDFInfo
- Publication number
- LV13258B LV13258B LVP-04-95A LV040095A LV13258B LV 13258 B LV13258 B LV 13258B LV 040095 A LV040095 A LV 040095A LV 13258 B LV13258 B LV 13258B
- Authority
- LV
- Latvia
- Prior art keywords
- skin
- retinoic acid
- dermis
- laser light
- upper layer
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title description 5
- 210000003491 skin Anatomy 0.000 claims abstract description 151
- 238000000034 method Methods 0.000 claims abstract description 114
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims abstract description 67
- 229960001727 tretinoin Drugs 0.000 claims abstract description 67
- 229930002330 retinoic acid Natural products 0.000 claims abstract description 65
- 210000004207 dermis Anatomy 0.000 claims abstract description 45
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 32
- 230000000699 topical effect Effects 0.000 claims abstract description 23
- 238000011282 treatment Methods 0.000 claims abstract description 21
- 210000002615 epidermis Anatomy 0.000 claims abstract description 17
- 230000006378 damage Effects 0.000 claims abstract description 15
- 208000014674 injury Diseases 0.000 claims abstract description 14
- 102000008186 Collagen Human genes 0.000 claims description 22
- 108010035532 Collagen Proteins 0.000 claims description 22
- 229920001436 collagen Polymers 0.000 claims description 21
- 230000001684 chronic effect Effects 0.000 claims description 20
- 208000002874 Acne Vulgaris Diseases 0.000 claims description 10
- 206010000496 acne Diseases 0.000 claims description 10
- 210000004204 blood vessel Anatomy 0.000 claims description 9
- 231100000241 scar Toxicity 0.000 claims description 8
- 208000032544 Cicatrix Diseases 0.000 claims description 7
- 230000037387 scars Effects 0.000 claims description 7
- 230000019612 pigmentation Effects 0.000 claims description 6
- 238000002203 pretreatment Methods 0.000 claims description 6
- 230000037303 wrinkles Effects 0.000 claims description 6
- 201000004681 Psoriasis Diseases 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 2
- 230000009172 bursting Effects 0.000 claims 8
- 230000009693 chronic damage Effects 0.000 claims 8
- 239000012678 infectious agent Substances 0.000 claims 6
- 239000002269 analeptic agent Substances 0.000 claims 4
- 201000004624 Dermatitis Diseases 0.000 claims 2
- 208000010668 atopic eczema Diseases 0.000 claims 2
- 206010040872 skin infection Diseases 0.000 claims 2
- 229940121668 Collagen stimulant Drugs 0.000 claims 1
- 230000001524 infective effect Effects 0.000 claims 1
- 230000001020 rhythmical effect Effects 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
- 239000005526 vasoconstrictor agent Substances 0.000 claims 1
- 230000008569 process Effects 0.000 abstract description 23
- 239000000356 contaminant Substances 0.000 abstract description 18
- 238000013532 laser treatment Methods 0.000 abstract description 14
- 206010052428 Wound Diseases 0.000 description 18
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 12
- 230000003213 activating effect Effects 0.000 description 10
- 230000008901 benefit Effects 0.000 description 10
- 230000000694 effects Effects 0.000 description 9
- 239000003921 oil Substances 0.000 description 9
- 239000011148 porous material Substances 0.000 description 8
- 229910052799 carbon Inorganic materials 0.000 description 7
- 238000002647 laser therapy Methods 0.000 description 6
- 230000003716 rejuvenation Effects 0.000 description 6
- 229910002804 graphite Inorganic materials 0.000 description 5
- 239000010439 graphite Substances 0.000 description 5
- 230000001939 inductive effect Effects 0.000 description 4
- 208000015181 infectious disease Diseases 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 208000004898 Herpes Labialis Diseases 0.000 description 3
- 206010067152 Oral herpes Diseases 0.000 description 3
- 230000008021 deposition Effects 0.000 description 3
- 238000004880 explosion Methods 0.000 description 3
- 230000008439 repair process Effects 0.000 description 3
- 210000001732 sebaceous gland Anatomy 0.000 description 3
- 229910019655 synthetic inorganic crystalline material Inorganic materials 0.000 description 3
- 230000029663 wound healing Effects 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- SHGAZHPCJJPHSC-UHFFFAOYSA-N Panrexin Chemical compound OC(=O)C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 239000002480 mineral oil Substances 0.000 description 2
- 235000010446 mineral oil Nutrition 0.000 description 2
- 239000000049 pigment Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 229940002683 retin-a Drugs 0.000 description 2
- 230000037390 scarring Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000012049 topical pharmaceutical composition Substances 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010019973 Herpes virus infection Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 229910052779 Neodymium Inorganic materials 0.000 description 1
- 208000015390 Sebaceous gland disease Diseases 0.000 description 1
- 206010040925 Skin striae Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 238000010306 acid treatment Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- JNDMLEXHDPKVFC-UHFFFAOYSA-N aluminum;oxygen(2-);yttrium(3+) Chemical compound [O-2].[O-2].[O-2].[Al+3].[Y+3] JNDMLEXHDPKVFC-UHFFFAOYSA-N 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000033115 angiogenesis Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000002316 cosmetic surgery Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 239000003193 general anesthetic agent Substances 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000003589 local anesthetic agent Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- QEFYFXOXNSNQGX-UHFFFAOYSA-N neodymium atom Chemical compound [Nd] QEFYFXOXNSNQGX-UHFFFAOYSA-N 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000000979 retarding effect Effects 0.000 description 1
- 201000004700 rosacea Diseases 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 201000010153 skin papilloma Diseases 0.000 description 1
- 230000008833 sun damage Effects 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- BWMISRWJRUSYEX-SZKNIZGXSA-N terbinafine hydrochloride Chemical compound Cl.C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 BWMISRWJRUSYEX-SZKNIZGXSA-N 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000007998 vessel formation Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 229910019901 yttrium aluminum garnet Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/203—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser applying laser energy to the outside of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
- A61B2017/00761—Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
- A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
- A61B2018/0047—Upper parts of the skin, e.g. skin peeling or treatment of wrinkles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/81—Preparation or application process involves irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Surgery (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Electromagnetism (AREA)
- Otolaryngology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Birds (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Laser Surgery Devices (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4733502A | 2002-01-14 | 2002-01-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LV13258B true LV13258B (en) | 2006-01-20 |
Family
ID=21948372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LVP-04-95A LV13258B (en) | 2002-01-14 | 2004-08-13 | Method for producing youthful-appearing, small-pored, and smooth skin |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP1476081B1 (fr) |
| JP (1) | JP2005514142A (fr) |
| KR (1) | KR20040075078A (fr) |
| CN (1) | CN1615106A (fr) |
| AT (1) | ATE540620T1 (fr) |
| AU (1) | AU2002332731B2 (fr) |
| BG (1) | BG108838A (fr) |
| BR (1) | BR0215510A (fr) |
| CA (1) | CA2472450A1 (fr) |
| CO (1) | CO5600990A2 (fr) |
| CZ (1) | CZ2004810A3 (fr) |
| EA (1) | EA008608B1 (fr) |
| EC (1) | ECSP045199A (fr) |
| EE (1) | EE200400103A (fr) |
| GE (1) | GEP20063953B (fr) |
| HR (1) | HRP20040629A2 (fr) |
| HU (1) | HUP0600678A3 (fr) |
| IS (1) | IS7392A (fr) |
| LT (1) | LT5290B (fr) |
| LV (1) | LV13258B (fr) |
| MX (1) | MXPA04006828A (fr) |
| NO (1) | NO340491B1 (fr) |
| NZ (1) | NZ534385A (fr) |
| PL (1) | PL371247A1 (fr) |
| SI (1) | SI21727A (fr) |
| SK (1) | SK2762004A3 (fr) |
| UA (1) | UA79106C2 (fr) |
| WO (1) | WO2003059144A2 (fr) |
| YU (1) | YU60904A (fr) |
| ZA (1) | ZA200406313B (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011054033A1 (fr) * | 2009-11-06 | 2011-05-12 | The Brand Factory Pty Ltd As Trustee For The Brand Factory Trust | Thérapies d'association utilisant une lumière non ablative et des agents topiques |
| US11794040B2 (en) | 2010-01-19 | 2023-10-24 | The Board Of Regents Of The University Of Texas System | Apparatuses and systems for generating high-frequency shockwaves, and methods of use |
| IT1402259B1 (it) * | 2010-10-15 | 2013-08-28 | Salvatore | Prodotti cosmetici e procedimento per il trattamento cosmetico anti-invecchiamento della pelle mediante detti prodotti cosmetici |
| AR087170A1 (es) | 2011-07-15 | 2014-02-26 | Univ Texas | Aparato para generar ondas de choque terapeuticas y sus aplicaciones |
| JP2015529131A (ja) | 2012-09-20 | 2015-10-05 | コーニンクレッカ フィリップス エヌ ヴェ | 皮膚治療方法及び装置 |
| RU2016106658A (ru) * | 2013-07-30 | 2017-09-01 | Конинклейке Филипс Н.В. | Лечебный прибор для лечения фракционным лазером по площади или линии |
| DE202015008939U1 (de) | 2015-11-09 | 2016-03-21 | Fb21 Vertriebs Gmbh | Dermabrasionsstick |
| CN109152605B (zh) | 2016-02-25 | 2022-04-19 | 通用医疗公司 | 紧致皮肤和其它组织的设备和方法 |
| WO2017165595A1 (fr) * | 2016-03-23 | 2017-09-28 | Soliton, Inc. | Système et procédé de nettoyage cutané par ondes acoustiques pulsées |
| TWI742110B (zh) | 2016-07-21 | 2021-10-11 | 美商席利通公司 | 具備改良電極壽命之快速脈波電動液壓脈衝產生裝置及使用該裝置生成壓縮聲波之方法 |
| BR112019017264A2 (pt) | 2017-02-19 | 2020-04-14 | Soliton Inc | ruptura óptica seletiva induzida a laser em meio biológico |
| GB2589798A (en) * | 2018-06-27 | 2021-06-09 | Lightsense Israel Ltd | Improvements in and to methods and apparatus for removal of skin pigmentation and tattoo ink |
| CN113747942A (zh) | 2019-04-03 | 2021-12-03 | 索里顿有限责任公司 | 透过非侵入性声波皮下切割处理组织和橘皮组织之系统、装置以及方法 |
| KR102239058B1 (ko) * | 2020-09-02 | 2021-04-13 | 주식회사 위즈메디 | 광 조사 장치 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5817089A (en) | 1991-10-29 | 1998-10-06 | Thermolase Corporation | Skin treatment process using laser |
| US5423803A (en) * | 1991-10-29 | 1995-06-13 | Thermotrex Corporation | Skin surface peeling process using laser |
| US6887260B1 (en) * | 1998-11-30 | 2005-05-03 | Light Bioscience, Llc | Method and apparatus for acne treatment |
-
2002
- 2002-08-28 HU HU0600678A patent/HUP0600678A3/hu active IP Right Revival
- 2002-08-28 BR BR0215510-9A patent/BR0215510A/pt not_active IP Right Cessation
- 2002-08-28 EE EEP200400103A patent/EE200400103A/xx unknown
- 2002-08-28 SI SI200220040A patent/SI21727A/sl not_active IP Right Cessation
- 2002-08-28 GE GE5676A patent/GEP20063953B/en unknown
- 2002-08-28 KR KR10-2004-7010917A patent/KR20040075078A/ko not_active Application Discontinuation
- 2002-08-28 EA EA200400951A patent/EA008608B1/ru not_active IP Right Cessation
- 2002-08-28 YU YU60904A patent/YU60904A/sh unknown
- 2002-08-28 JP JP2003559315A patent/JP2005514142A/ja active Pending
- 2002-08-28 AT AT02806427T patent/ATE540620T1/de active
- 2002-08-28 CN CNA028271262A patent/CN1615106A/zh active Pending
- 2002-08-28 CA CA002472450A patent/CA2472450A1/fr not_active Abandoned
- 2002-08-28 EP EP02806427A patent/EP1476081B1/fr not_active Expired - Lifetime
- 2002-08-28 PL PL02371247A patent/PL371247A1/xx not_active Application Discontinuation
- 2002-08-28 SK SK276-2004A patent/SK2762004A3/sk not_active Application Discontinuation
- 2002-08-28 UA UA20040806798A patent/UA79106C2/uk unknown
- 2002-08-28 MX MXPA04006828A patent/MXPA04006828A/es not_active Application Discontinuation
- 2002-08-28 WO PCT/US2002/027570 patent/WO2003059144A2/fr active IP Right Grant
- 2002-08-28 AU AU2002332731A patent/AU2002332731B2/en not_active Ceased
- 2002-08-28 CZ CZ2004810A patent/CZ2004810A3/cs unknown
- 2002-08-28 NZ NZ534385A patent/NZ534385A/en not_active IP Right Cessation
-
2004
- 2004-07-12 HR HR20040629A patent/HRP20040629A2/hr not_active Application Discontinuation
- 2004-07-21 EC EC2004005199A patent/ECSP045199A/es unknown
- 2004-08-04 CO CO04075565A patent/CO5600990A2/es not_active Application Discontinuation
- 2004-08-10 IS IS7392A patent/IS7392A/is unknown
- 2004-08-10 BG BG108838A patent/BG108838A/bg unknown
- 2004-08-10 ZA ZA200406313A patent/ZA200406313B/en unknown
- 2004-08-11 LT LT2004077A patent/LT5290B/lt not_active IP Right Cessation
- 2004-08-13 LV LVP-04-95A patent/LV13258B/en unknown
- 2004-08-13 NO NO20043379A patent/NO340491B1/no not_active IP Right Cessation
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