LV11630B - T cell antigen receptor v region proteins and methods of preparation thereof - Google Patents

T cell antigen receptor v region proteins and methods of preparation thereof Download PDF

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Publication number
LV11630B
LV11630B LVP-96-313A LV960313A LV11630B LV 11630 B LV11630 B LV 11630B LV 960313 A LV960313 A LV 960313A LV 11630 B LV11630 B LV 11630B
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LV
Latvia
Prior art keywords
region
sequence
antigen receptor
gene
protein
Prior art date
Application number
LVP-96-313A
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English (en)
Latvian (lv)
Other versions
LV11630A (lv
Inventor
Savvas C Makrides
Patrick C Kung
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T Cell Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by T Cell Sciences Inc filed Critical T Cell Sciences Inc
Publication of LV11630A publication Critical patent/LV11630A/xx
Publication of LV11630B publication Critical patent/LV11630B/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Plant Pathology (AREA)
  • Neurology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
LVP-96-313A 1994-01-13 1996-07-23 T cell antigen receptor v region proteins and methods of preparation thereof LV11630B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/181,492 US5552300A (en) 1994-01-13 1994-01-13 T cell antigen receptor V region proteins and methods of preparation thereof
PCT/US1995/000408 WO1995019435A2 (en) 1994-01-13 1995-01-12 T cell antigen receptor v region proteins and methods of preparation thereof

Publications (2)

Publication Number Publication Date
LV11630A LV11630A (lv) 1996-12-20
LV11630B true LV11630B (en) 1997-08-20

Family

ID=22664497

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-96-313A LV11630B (en) 1994-01-13 1996-07-23 T cell antigen receptor v region proteins and methods of preparation thereof

Country Status (21)

Country Link
US (1) US5552300A (ko)
EP (1) EP0738322A1 (ko)
JP (1) JPH10501961A (ko)
KR (1) KR100213396B1 (ko)
AU (1) AU700661B2 (ko)
BR (1) BR9506612A (ko)
CA (1) CA2181171A1 (ko)
CZ (1) CZ9602009A3 (ko)
EE (1) EE03287B1 (ko)
FI (1) FI962844A (ko)
HU (1) HUT75551A (ko)
IL (1) IL112316A0 (ko)
LV (1) LV11630B (ko)
MX (1) MX9602750A (ko)
NO (1) NO962921L (ko)
NZ (2) NZ279605A (ko)
PL (1) PL181072B1 (ko)
SG (1) SG52342A1 (ko)
SK (1) SK90696A3 (ko)
WO (1) WO1995019435A2 (ko)
ZA (1) ZA95261B (ko)

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US6113903A (en) * 1989-03-21 2000-09-05 The Immune Response Corporation Peptides and methods against diabetes
US20060235209A9 (en) * 1997-03-10 2006-10-19 Jin-An Jiao Use of anti-tissue factor antibodies for treating thromboses
US20040229282A1 (en) * 1997-03-10 2004-11-18 Sunol Molecular Corporation Antibodies for inhibiting blood coagulation and methods of use thereof
US5986065A (en) * 1997-03-10 1999-11-16 Sunol Molecular Corporation Antibodies for inhibiting blood coagulation and methods of use thereof
US7749498B2 (en) * 1997-03-10 2010-07-06 Genentech, Inc. Antibodies for inhibiting blood coagulation and methods of use thereof
US20030109680A1 (en) * 2001-11-21 2003-06-12 Sunol Molecular Corporation Antibodies for inhibiting blood coagulation and methods of use thereof
JP4932086B2 (ja) 1999-04-08 2012-05-16 インターセル ユーエスエイ、インコーポレイテッド 経皮的免疫のための乾燥製剤
US7658926B2 (en) * 2001-09-14 2010-02-09 Opexa Pharmaceuticals, Inc. Autologous T-cell vaccines materials and methods
US20030190705A1 (en) * 2001-10-29 2003-10-09 Sunol Molecular Corporation Method of humanizing immune system molecules
WO2004015070A2 (en) * 2002-08-08 2004-02-19 Baylor College Of Medicine Isolation and identification of t cells
MXPA05013789A (es) * 2003-06-19 2006-06-27 Tanox Inc Composiciones y metodos para tratar los desordenes relacionados con la coagulacion.
EP1768742A4 (en) * 2004-07-06 2007-10-17 Transpharma Medical Ltd ADMINISTRATION SYSTEM FOR TRANSDERMAL IMMUNIZATION
US7994298B2 (en) 2004-09-24 2011-08-09 Trustees Of Dartmouth College Chimeric NK receptor and methods for treating cancer
US20070009542A1 (en) 2005-07-05 2007-01-11 Galit Levin Method and device for transdermal immunization
CN101242869B (zh) 2005-09-02 2010-05-26 Iomai公司 经皮递送疫苗和透皮递送药物的装置及其应用
PL2016414T3 (pl) * 2006-05-05 2016-01-29 Opexa Therapeutics Szczepionka z komórek T
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
CN102573883A (zh) 2009-06-12 2012-07-11 疫苗技术公司 用于促进细胞-介导的免疫应答的方法和组合物
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
WO2013033626A2 (en) 2011-08-31 2013-03-07 Trustees Of Dartmouth College Nkp30 receptor targeted therapeutics
ES2719495T3 (es) 2012-05-07 2019-07-10 Dartmouth College Anticuerpo dirigido contra b7-h6, proteínas de fusión, y métodos de uso de los mismos
WO2014044690A1 (en) 2012-09-18 2014-03-27 Valneva Austria Gmbh Improved vaccines

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713332A (en) * 1984-01-13 1987-12-15 The Ontario Cancer Institute T cell specific CDNA clone
US4873190A (en) * 1984-06-13 1989-10-10 Massachusetts Institute Of Technology Heterodimeric T lymphocyte receptor
SG70553A1 (en) * 1984-03-01 2000-02-22 Univ Leland Stanford Junior T-cell receptor-specific for antigen polypeptides and related polynucleotides
US4845026A (en) * 1985-12-03 1989-07-04 T Cell Sciences, Inc. Assay systems for detecting cell-free T cell antigen receptor related molecules and the clinical utilities of the assays
US5260223A (en) * 1986-07-03 1993-11-09 President & Fellows Of Harvard College Methods for detection of human gamma, γ T cell receptor
US5185250A (en) * 1986-07-03 1993-02-09 T Cell Sciences, Inc. Human γ, δT cell antigen receptor polypeptides and nucleic acids
US5024940A (en) * 1987-02-19 1991-06-18 T Cell Sciences, Inc. Nucleic acids encoding the delta chain of the T cell antigen receptor
US5340921A (en) * 1986-07-03 1994-08-23 T Cell Sciences, Inc. Γ, δT cell receptor and methods and detection
EP0712928A2 (en) * 1987-06-23 1996-05-22 The Board Of Trustees Of The Leland Stanford Junior University T cell antigen receptor
US5223426A (en) * 1988-12-15 1993-06-29 T Cell Sciences, Inc. Monoclonal antibodies reactive with defined regions of the t-cell antigen receptor
EP0463101B2 (en) * 1989-03-21 2003-03-19 The Immune Response Corporation Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations
WO1990014068A2 (en) * 1989-05-02 1990-11-29 Irun Robert Cohen Anti-ergotypic t cells for the treatment or prevention of autoimmune diseases and methods of use thereof
CA2072356A1 (en) * 1989-12-29 1991-06-30 James L. Urban Diagnosis and treatment of diseases
US5216132A (en) * 1990-01-12 1993-06-01 Protein Design Labs, Inc. Soluble t-cell antigen receptor chimeric antigens
ES2090335T3 (es) * 1990-05-01 1996-10-16 Univ Leland Stanford Junior Composiciones para uso en un metodo para tratar a un ser humano que padece esclerosis multiple.
KR930701620A (ko) * 1990-08-09 1993-06-12 프레드릭 에이. 란길레 재조합 dna 백터를 이용하여 인체 t-세포 리셉터 성분에 대한 단일 클론성 항체의 제조방법
JPH06502997A (ja) * 1991-02-12 1994-04-07 ルセル　ユクラフ ヒトＴリンパ球レセプターのβ鎖の可変領域をコードするヌクレオチド配列対応するペプチドセグメント並びに診断及び治療への利用
JPH07502977A (ja) * 1991-05-31 1995-03-30 ゾーマ・コーポレーション 免疫関連疾患用治療薬としてのｔ細胞レセプターペプチド
JPH06511241A (ja) * 1991-09-23 1994-12-15 ジェネンテク，インコーポレイテッド 自己免疫疾患の診断および治療
US5333487A (en) * 1991-11-15 1994-08-02 Hughes Aircraft Company Spark-excited fluorescence sensor
US5212091A (en) * 1992-03-02 1993-05-18 Monsanto Company Method of producing tissue factor pathway inhibitor

Also Published As

Publication number Publication date
ZA95261B (en) 1995-11-14
AU700661B2 (en) 1999-01-14
WO1995019435A3 (en) 1995-08-24
WO1995019435A2 (en) 1995-07-20
PL319374A1 (en) 1997-08-04
US5552300A (en) 1996-09-03
PL181072B1 (pl) 2001-05-31
SG52342A1 (en) 1999-06-22
BR9506612A (pt) 1997-09-16
CZ9602009A3 (en) 1997-12-17
CA2181171A1 (en) 1995-07-20
KR100213396B1 (ko) 1999-08-02
LV11630A (lv) 1996-12-20
HUT75551A (en) 1997-05-28
FI962844A (fi) 1996-08-29
NZ279605A (en) 1999-01-28
HU9601908D0 (en) 1996-09-30
FI962844A0 (fi) 1996-07-12
SK90696A3 (en) 1997-07-09
NZ332715A (en) 2000-06-23
KR970700772A (ko) 1997-02-12
IL112316A0 (en) 1995-03-30
MX9602750A (es) 1997-05-31
EE03287B1 (et) 2000-08-15
NO962921D0 (no) 1996-07-11
JPH10501961A (ja) 1998-02-24
NO962921L (no) 1996-09-02
EP0738322A1 (en) 1996-10-23
AU1678495A (en) 1995-08-01

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