LV11463B - Process for the preparation of substituted 4,6-diamino-5-cyanopyrimidines - Google Patents

Process for the preparation of substituted 4,6-diamino-5-cyanopyrimidines Download PDF

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Publication number
LV11463B
LV11463B LVP-96-53A LV960053A LV11463B LV 11463 B LV11463 B LV 11463B LV 960053 A LV960053 A LV 960053A LV 11463 B LV11463 B LV 11463B
Authority
LV
Latvia
Prior art keywords
formula
water
mixture
alkali metal
amino
Prior art date
Application number
LVP-96-53A
Other languages
English (en)
Latvian (lv)
Other versions
LV11463A (lv
Inventor
Assercq Jean-Marie
Heinz P Schwemlein
Jeffrey W Perine
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of LV11463A publication Critical patent/LV11463A/xx
Publication of LV11463B publication Critical patent/LV11463B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
LVP-96-53A 1993-07-26 1996-02-26 Process for the preparation of substituted 4,6-diamino-5-cyanopyrimidines LV11463B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9714193A 1993-07-26 1993-07-26
US21098094A 1994-03-21 1994-03-21
PCT/EP1994/002312 WO1995003282A2 (en) 1993-07-26 1994-07-14 Process for the preparation of substituted 4,6-diamino-5-cyanopyrimidines

Publications (2)

Publication Number Publication Date
LV11463A LV11463A (lv) 1996-08-20
LV11463B true LV11463B (en) 1996-12-20

Family

ID=26792702

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-96-53A LV11463B (en) 1993-07-26 1996-02-26 Process for the preparation of substituted 4,6-diamino-5-cyanopyrimidines

Country Status (15)

Country Link
EP (1) EP0711285A1 (xx)
JP (1) JPH09500632A (xx)
CN (1) CN1128024A (xx)
AU (1) AU7385994A (xx)
BG (1) BG100366A (xx)
BR (1) BR9407024A (xx)
CA (1) CA2166989A1 (xx)
CZ (1) CZ22496A3 (xx)
FI (1) FI960332A (xx)
HU (1) HUT73357A (xx)
IL (1) IL110425A0 (xx)
LV (1) LV11463B (xx)
NO (1) NO960307L (xx)
SK (1) SK10396A3 (xx)
WO (1) WO1995003282A2 (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1007516T3 (da) * 1997-08-27 2004-10-18 Novartis Ag Dicyclanylpolymorfe og hydrater og fremstilling deraf
US8273899B2 (en) 2007-04-19 2012-09-25 Nippon Soda Co., Ltd. Method for production of N-(2-amino-1,2-dicyanovinyl)imidates, method for production of N-(2-amino-1,2-dicyanovinyl)formamidine, and method for production of aminoimidazole derivatives
CN102250017A (zh) * 2011-06-15 2011-11-23 扬州天和药业有限公司 地昔尼尔的一种合成方法
CN102399193A (zh) * 2011-12-15 2012-04-04 连云港市亚晖医药化工有限公司 4,6-二氨基-2-环丙胺基-5-腈基嘧啶的制备方法
CN104130197A (zh) * 2014-07-29 2014-11-05 华中农业大学 2,4,6-三氨基-5-氰基嘧啶的化学合成方法
CN104649982B (zh) * 2015-02-26 2016-12-07 齐鲁晟华制药有限公司 一种地昔尼尔的制备方法
CN107056655B (zh) * 2017-01-22 2018-12-04 营口三征新科技化工有限公司 一种1-氨基-1-氰氨基-2,2-二氰乙烯钠盐的制备方法
CN106966922B (zh) * 2017-03-28 2020-10-27 中国科学院大学 一种功能化取代的二氰基乙烯类化合物的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1135913B (de) * 1960-11-08 1962-09-06 Bayer Ag Verfahren zur Herstellung von 2-Methyl-4-amino-5-cyanpyrimidin
US3226424A (en) * 1962-10-03 1965-12-28 Hoffmann La Roche Process for preparing 2-lower alkoxy-1,1-dicyanoethylene and 2-amino-1,1-dicyanoethylene
US4783468A (en) * 1986-04-30 1988-11-08 Ciba-Geigy Corporation Insecticidal 5-pyrimidine carbonitriles

Also Published As

Publication number Publication date
NO960307D0 (no) 1996-01-25
FI960332A0 (fi) 1996-01-24
EP0711285A1 (en) 1996-05-15
BR9407024A (pt) 1996-09-10
HUT73357A (en) 1996-07-29
IL110425A0 (en) 1994-10-21
CA2166989A1 (en) 1995-02-02
CN1128024A (zh) 1996-07-31
JPH09500632A (ja) 1997-01-21
WO1995003282A2 (en) 1995-02-02
WO1995003282A3 (en) 1995-04-13
SK10396A3 (en) 1996-09-04
HU9503959D0 (en) 1996-03-28
NO960307L (no) 1996-01-25
AU7385994A (en) 1995-02-20
FI960332A (fi) 1996-01-24
LV11463A (lv) 1996-08-20
CZ22496A3 (en) 1996-04-17
BG100366A (en) 1996-07-31

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