LU90843I2 - Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables - Google Patents

Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables

Info

Publication number
LU90843I2
LU90843I2 LU90843C LU90843C LU90843I2 LU 90843 I2 LU90843 I2 LU 90843I2 LU 90843 C LU90843 C LU 90843C LU 90843 C LU90843 C LU 90843C LU 90843 I2 LU90843 I2 LU 90843I2
Authority
LU
Luxembourg
Prior art keywords
crystals
solvent
compound
starlix
nateglinide
Prior art date
Application number
LU90843C
Other languages
English (en)
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27169694&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU90843(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of LU90843I2 publication Critical patent/LU90843I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU90843C 1991-07-30 2001-09-28 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables LU90843I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18969691 1991-07-30
JP19945391 1991-08-08
CA002114678A CA2114678C (fr) 1991-07-30 1994-02-01 Cristaux de n-(trans-4-isopropylcyclohexylcarbonyl)- d-phenylalanine et methodes pour les preparer

Publications (1)

Publication Number Publication Date
LU90843I2 true LU90843I2 (fr) 2002-02-04

Family

ID=27169694

Family Applications (2)

Application Number Title Priority Date Filing Date
LU90843C LU90843I2 (fr) 1991-07-30 2001-09-28 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables
LU90846C LU90846I2 (fr) 1991-07-30 2001-10-03 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables

Family Applications After (1)

Application Number Title Priority Date Filing Date
LU90846C LU90846I2 (fr) 1991-07-30 2001-10-03 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables

Country Status (11)

Country Link
US (1) US5488150A (fr)
EP (1) EP0526171B1 (fr)
JP (1) JP2508949B2 (fr)
AT (1) ATE149483T1 (fr)
BR (1) BR1100807A (fr)
CA (1) CA2114678C (fr)
DE (2) DE10199058I2 (fr)
DK (1) DK0526171T3 (fr)
ES (1) ES2100291T3 (fr)
LU (2) LU90843I2 (fr)
NL (1) NL300063I2 (fr)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2271865C (fr) 1996-11-15 2003-10-14 Ajinomoto Co., Inc. Preparation en comprimes
GB9713730D0 (en) 1997-06-30 1997-09-03 Ciba Geigy Ag Organic compounds
AR028299A1 (es) 1999-09-17 2003-05-07 Novartis Ag Una composicion farmaceutica que comprende nateglinida, un proceso para su preparacion y el uso de dicha composicion para la preparacion de un medicamento para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con diabetes.
US6878749B2 (en) * 1999-09-17 2005-04-12 Novartis Ag Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
US6559188B1 (en) 1999-09-17 2003-05-06 Novartis Ag Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
DE122008000018I1 (de) 2000-01-21 2008-08-14 Novartis Pharma Ag Zusammensetzungen bestehend aus Dipeptidylpeptidase-IV Inhibitoren und Antidiabetica
PE20020617A1 (es) 2000-08-22 2002-08-05 Novartis Ag Composicion que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina o un sensibilizante a la insulina
DK1334962T3 (da) * 2000-10-18 2007-12-10 Ajinomoto Kk Fremgangsmåder til fremstilling af acylphenylalanin
MXPA03003484A (es) * 2000-10-18 2003-07-14 Ajinomoto Kk Procedimiento para producir cristales de nateglinida.
EP1334720B1 (fr) * 2000-10-24 2008-09-03 Ajinomoto Co., Inc. Preparations contenant du nateglinide
JP4225057B2 (ja) * 2000-10-24 2009-02-18 味の素株式会社 ナテグリニドｂ型結晶の製造方法
SI1334721T1 (sl) * 2000-10-24 2009-08-31 Ajinomoto Kk Hidrofilni farmacevtski pripravki, ki vsebujejo nateglinid
AR035425A1 (es) * 2001-01-30 2004-05-26 Teijin Ltd Cristal de diclorhidrato del acido 3-(3-amidinofenil)-5-[({[1-(iminoetil)-4-piperidil]metil}amino)metil]benzoico y proceso para prepararlo
WO2003022251A1 (fr) * 2001-09-12 2003-03-20 Alembic Limited Nouvelle forme de cristal stable de n-(trans-4-isopropylcyclohexyl carbonyl)-d-phenylalanine et procede de preparation correspondant
TW200304813A (en) * 2002-03-11 2003-10-16 Novartis Ag Salts of organic acid
US7411089B2 (en) 2002-04-15 2008-08-12 Ajinomoto Co., Inc. Nateglinide crystals
EP2264004A1 (fr) 2002-04-15 2010-12-22 Ajinomoto Co., Inc. Nouveau crystals des nateglinide
CN1304366C (zh) * 2002-04-15 2007-03-14 诺瓦提斯公司 N－(反式－4－异丙基环己基羰基)－d－苯丙氨酸的晶形
MXNL04000084A (es) * 2002-04-29 2006-02-28 Biocon Ltd Forma novedosa de n-(trans-4-isopropilciclohexilcarbonil)-d-fenilalanina.
EP1487782A1 (fr) * 2002-07-03 2004-12-22 Teva Pharmaceutical Industries Ltd. Procede de preparation du nateglinide et intermediaires
US6861553B2 (en) * 2002-07-03 2005-03-01 Teva Pharmaceuticals Industries Ltd. Process for preparing nateglinide and intermediates thereof
US7420084B2 (en) * 2002-07-18 2008-09-02 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7358390B2 (en) * 2002-07-18 2008-04-15 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7148376B2 (en) * 2002-07-18 2006-12-12 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7534913B2 (en) * 2002-07-18 2009-05-19 Teva Pharmaceutica Industries Ltd. Crystalline form of nateglinide
US20050075400A1 (en) * 2002-07-18 2005-04-07 Ronit Yahalomi Polymorphic forms of nateglinide
AU2003262928A1 (en) * 2002-08-28 2004-03-19 Dr. Reddy's Laboratories Limited Crystalline form of nateglinide and process for preparation thereof
EP1616886A4 (fr) * 2003-02-18 2006-06-14 Konishi Co Ltd Resine durcissable, son procede de production et composition de resine durcissable
HU227073B1 (hu) 2003-07-10 2010-06-28 Richter Gedeon Nyrt Eljárás királisan tiszta N-(transz-4-izopropil-ciklohexilkarbonil)-D-fenil-alanin (nateglinid) és kristálymódosulatainak elõállítására, valamint a G-kristálymódosulata
JP2007528858A (ja) * 2004-05-07 2007-10-18 テバ ファーマシューティカル インダストリーズ リミティド ナテグリニドの多形形態
US7425648B2 (en) 2005-01-03 2008-09-16 A.M.S.A. Anonima Materie Sintetiche E. Affini S.P.A. Process for the preparation of nateglinide, preferably in B-form
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
CA2622608C (fr) 2005-09-14 2014-08-19 Takeda Pharmaceutical Company Limited Administration d'inhibiteurs de dipeptidyl peptidase
CN101415668B (zh) * 2006-03-31 2013-06-19 味之素株式会社 羧酸酰氯化合物的制造方法
CN103951583B (zh) * 2006-12-06 2016-01-06 科内图斯医药公司 一种抑制剂的结晶形式
BRPI1010600A2 (pt) 2009-05-15 2016-03-15 Novartis Ag aril piridina como inibidores de aldosterona sintase
EA019511B1 (ru) 2009-05-28 2014-04-30 Новартис Аг Замещенные производные аминопропионовой кислоты в качестве ингибиторов неприлизина
MA33364B1 (fr) 2009-05-28 2012-06-01 Novartis Ag Dérivés aminobutyriques substitués en tant qu'inhibiteurs de néprilysine
WO2011041293A1 (fr) 2009-09-30 2011-04-07 Takeda Pharmaceutical Company Limited Dérivés pyrazolo [1, 5—a] pyrimidines comme inhibiteurs de kinase 1 régulatrice de signal d'apoptose
EP2993169B1 (fr) 2009-11-17 2017-12-20 Novartis AG Dérivés de l'arylpyridine comme inhibiteurs de l'aldosterone synthase
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
EP2507234B1 (fr) 2009-11-30 2014-03-12 Novartis AG Dérivés d'imidazole en tant qu'inhibiteurs de l'aldostérone synthase
CN102834393B (zh) 2010-02-03 2015-07-22 武田药品工业株式会社 细胞凋亡信号调节激酶1抑制剂
US8673974B2 (en) 2010-11-16 2014-03-18 Novartis Ag Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
US8877815B2 (en) 2010-11-16 2014-11-04 Novartis Ag Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
UY35144A (es) 2012-11-20 2014-06-30 Novartis Ag Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
SI2956464T1 (en) 2013-02-14 2018-08-31 Novartis Ag Substituted bisphenyl butanoic phosphonic acid derivatives as NEP inhibitors (neutral endopeptidases)
UY35671A (es) 2013-07-25 2015-02-27 Novartis Ag Bioconjugados de polipéptidos de apelina sintética
SG11201600211XA (en) 2013-07-25 2016-02-26 Novartis Ag Cyclic polypeptides for the treatment of heart failure
MA41580A (fr) 2015-01-23 2017-11-29 Novartis Ag Conjugués d'acides gras de l'apeline synthétique présentant une demi-vie améliorée
UY38072A (es) 2018-02-07 2019-10-01 Novartis Ag Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos
CN109369443A (zh) * 2018-11-05 2019-02-22 扬子江药业集团江苏海慈生物药业有限公司 一种新的那格列奈h晶型的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US196222A (en) * 1877-10-16 Improvement in belt-tighteners
JPS6354321A (ja) * 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤

Also Published As

Publication number Publication date
ATE149483T1 (de) 1997-03-15
US5488150A (en) 1996-01-30
DE69217762D1 (de) 1997-04-10
ES2100291T3 (es) 1997-06-16
CA2114678C (fr) 1999-04-27
JPH05208943A (ja) 1993-08-20
NL300063I1 (nl) 2001-12-01
DE69217762T2 (de) 1997-10-09
JP2508949B2 (ja) 1996-06-19
DE10199058I1 (de) 2002-01-24
EP0526171B1 (fr) 1997-03-05
EP0526171A2 (fr) 1993-02-03
LU90846I2 (fr) 2002-02-04
CA2114678A1 (fr) 1995-08-02
BR1100807A (pt) 1999-12-28
NL300063I2 (nl) 2002-02-01
DE10199058I2 (de) 2006-04-27
DK0526171T3 (da) 1997-08-25
EP0526171A3 (en) 1993-05-05

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