JPS55153753A - New synthesis of 5-halogeno-2-methylaminobenzophenone - Google Patents

New synthesis of 5-halogeno-2-methylaminobenzophenone

Info

Publication number
JPS55153753A
JPS55153753A JP6094479A JP6094479A JPS55153753A JP S55153753 A JPS55153753 A JP S55153753A JP 6094479 A JP6094479 A JP 6094479A JP 6094479 A JP6094479 A JP 6094479A JP S55153753 A JPS55153753 A JP S55153753A
Authority
JP
Japan
Prior art keywords
methylaminobenzophenone
halogeno
halogenoamide
halogenoimide
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6094479A
Other languages
Japanese (ja)
Inventor
Tsutomu Sugasawa
Tatsuro Toyoda
Kazuyuki Sasakura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP6094479A priority Critical patent/JPS55153753A/en
Publication of JPS55153753A publication Critical patent/JPS55153753A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To prepare a 5-halogeno-2-methylaminobenzophenone useful as an intermediate for the synthesis of medicines, e.g. diazepam etc., ecomonically, in an industrial scale, by reacting a specific benzophenone derivative with an N-halogenoimide or an N-halogenoamide.
CONSTITUTION: (A) 2-Methylamino-2'-halogenated benzophenone I (X is H or halogen) and (B) an N-halogenoimide (e.g. N-chlorosuccinimide) or an N-halogenoamide (e.g. N-chloroacetamide) are heated and refluxed in a solvent, e.g. tetrahydrofuran. The formed imide or amide is filtered off and thereafter the filtrate is concentrated and the residue is purified e.g. by recrystallization to give the compound II (Y is halogen).
COPYRIGHT: (C)1980,JPO&Japio
JP6094479A 1979-05-17 1979-05-17 New synthesis of 5-halogeno-2-methylaminobenzophenone Pending JPS55153753A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6094479A JPS55153753A (en) 1979-05-17 1979-05-17 New synthesis of 5-halogeno-2-methylaminobenzophenone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6094479A JPS55153753A (en) 1979-05-17 1979-05-17 New synthesis of 5-halogeno-2-methylaminobenzophenone

Publications (1)

Publication Number Publication Date
JPS55153753A true JPS55153753A (en) 1980-11-29

Family

ID=13156991

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6094479A Pending JPS55153753A (en) 1979-05-17 1979-05-17 New synthesis of 5-halogeno-2-methylaminobenzophenone

Country Status (1)

Country Link
JP (1) JPS55153753A (en)

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