LU81453A1 - Nouveaux derives de l'indole,leur preparation et leur application comme medicaments - Google Patents

Nouveaux derives de l'indole,leur preparation et leur application comme medicaments Download PDF

Info

Publication number
LU81453A1
LU81453A1 LU81453A LU81453A LU81453A1 LU 81453 A1 LU81453 A1 LU 81453A1 LU 81453 A LU81453 A LU 81453A LU 81453 A LU81453 A LU 81453A LU 81453 A1 LU81453 A1 LU 81453A1
Authority
LU
Luxembourg
Prior art keywords
group
indole
carbon atoms
signifies
formula
Prior art date
Application number
LU81453A
Other languages
English (en)
French (fr)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of LU81453A1 publication Critical patent/LU81453A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B13/00—Bundling articles
    • B65B13/18—Details of, or auxiliary devices used in, bundling machines or bundling tools
    • B65B13/24—Securing ends of binding material
    • B65B13/26—Securing ends of binding material by knotting
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LU81453A 1978-07-03 1979-07-02 Nouveaux derives de l'indole,leur preparation et leur application comme medicaments LU81453A1 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
CH724078 1978-07-03
CH724078 1978-07-03
CH723578 1978-07-03
CH723578 1978-07-03
CH49179 1979-01-18
CH49679 1979-01-18
CH49679 1979-01-18
CH49179 1979-01-18

Publications (1)

Publication Number Publication Date
LU81453A1 true LU81453A1 (fr) 1980-02-14

Family

ID=27427897

Family Applications (1)

Application Number Title Priority Date Filing Date
LU81453A LU81453A1 (fr) 1978-07-03 1979-07-02 Nouveaux derives de l'indole,leur preparation et leur application comme medicaments

Country Status (15)

Country Link
US (1) US4304915A (de)
AU (1) AU4857379A (de)
DE (1) DE2925448A1 (de)
DK (1) DK266479A (de)
ES (1) ES482117A1 (de)
FI (1) FI792009A (de)
FR (1) FR2430419A1 (de)
GB (1) GB2027018A (de)
IL (1) IL57708A0 (de)
LU (1) LU81453A1 (de)
NL (1) NL7905079A (de)
PT (1) PT69860A (de)
SU (1) SU826954A3 (de)
WO (1) WO1980000152A1 (de)
YU (1) YU160479A (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2935062A1 (de) * 1978-09-06 1980-03-20 Degussa Substituierte aminoalkylguanidine, deren herstellung und arzneimittel
DE3029980A1 (de) * 1980-08-08 1982-03-11 Boehringer Mannheim Gmbh, 6800 Mannheim Indolderivate und verfahren zu ihrer herstellung
DE3030047A1 (de) * 1980-08-08 1982-03-11 Boehringer Mannheim Gmbh, 6800 Mannheim Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3115993A1 (de) * 1981-04-13 1982-11-11 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue indol-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die diese verbindungen enthalten
DE3423429A1 (de) * 1984-06-26 1986-01-02 Beiersdorf Ag, 2000 Hamburg Substituierte phenoxyalkylaminopropanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
DE3424685A1 (de) * 1984-07-05 1986-02-06 Beiersdorf Ag, 2000 Hamburg Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
US4704390A (en) * 1986-02-13 1987-11-03 Warner-Lambert Company Phenyl and heterocyclic tetrahydropyridyl alkoxy-benzheterocyclic compounds as antipsychotic agents
DE3721260A1 (de) * 1987-06-27 1989-01-12 Beiersdorf Ag Neue indolylpropanole, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5229412A (en) * 1988-03-25 1993-07-20 The Board Of Trustees Of The Leland Stanford Junior University Method for relieving anxiety using 5-hydroxytryptamine-1a-receptor-binding compounds
US5013761A (en) * 1988-06-03 1991-05-07 Eli Lilly And Company Serotonin antagonists
FR2640969B1 (de) * 1988-12-23 1991-11-22 Midy Spa
CA2080475C (en) * 1990-05-10 2001-04-17 Bertrand Leo Chenard Neuroprotective indolone and related derivatives
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
PL179448B1 (pl) * 1994-01-31 2000-09-29 Pfizer Neuroochronne zwiazki chromanoloweoraz kompozycje farmaceutyczne zawierajace te zwiazki PL PL PL PL PL
US5536749A (en) * 1994-10-13 1996-07-16 Sl Pharmaceuticals, Inc. Method for attenuation of sympathetic nervous system activity or onset of migraine by selectively metabolized beta-blocking agents
US5789402A (en) * 1995-01-17 1998-08-04 Eli Lilly Company Compounds having effects on serotonin-related systems
US5741789A (en) 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5614523A (en) * 1995-01-17 1997-03-25 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5627196A (en) * 1995-01-17 1997-05-06 Eli Lilly And Company Compounds having effects on serotonin-related systems
WO2000038685A1 (en) * 1998-12-30 2000-07-06 Eli Lilly And Company Solution phase synthesis of compounds including amine alcohol functionality
CA2716369C (en) * 1999-05-24 2013-05-14 Mitsubishi Tanabe Pharma Corporation Phenoxypropylamine compounds
US7144898B2 (en) * 1999-12-20 2006-12-05 Eli Lilly And Company Indole derivatives for the treatment of depression and anxiety
AR028948A1 (es) * 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
AR035230A1 (es) * 2001-03-19 2004-05-05 Astrazeneca Ab Compuestos de bencimidazol, proceso para su preparacion, composicion farmaceutica, proceso para la preparacion de dicha composicion farmaceutica, y usos de estos compuestos para la elaboracion de medicamentos
SE0101038D0 (sv) * 2001-03-23 2001-03-23 Astrazeneca Ab Novel compounds
TW200738634A (en) * 2005-08-02 2007-10-16 Astrazeneca Ab New salt
CN102382032A (zh) * 2010-08-30 2012-03-21 广州医学院 1-(苯基)-4-[3-(4-吲哚氧基)-2-羟基丙基]哌嗪衍生物及其盐、制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1129072A (en) * 1966-02-01 1968-10-02 Ici Ltd Benzofuran and indole derivatives
CH469002A (de) * 1966-06-21 1969-02-28 Sandoz Ag Verfahren zur Herstellung neuer Indolderivate
FR1547056A (fr) * 1966-12-13 1968-11-22 Sandoz Sa Dérivés de l'indole et leur préparation
US3705907A (en) * 1970-02-19 1972-12-12 Sandoz Ltd 4-(2-hydroxy)-3-aminopropoxy)-indole derivatives
US3751429A (en) * 1970-03-24 1973-08-07 Sandoz Ltd 4-(3-amino-2-substituted propoxy)indole derivatives
CH540253A (de) * 1971-01-07 1973-08-15 Sandoz Ag Verfahren zur Herstellung neuer Indole
DE2337461A1 (de) * 1973-07-24 1975-02-06 Boehringer Mannheim Gmbh Neue indolderivate und verfahren zu deren herstellung
US4076829A (en) * 1974-11-16 1978-02-28 Boehringer Mannheim Gmbh Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases
DE2633839A1 (de) * 1975-08-07 1977-02-24 Sandoz Ag Neue 4-aminopropoxyindolderivate, ihre herstellung und verwendung

Also Published As

Publication number Publication date
DE2925448A1 (de) 1980-01-24
FR2430419A1 (fr) 1980-02-01
DK266479A (da) 1980-02-04
WO1980000152A1 (en) 1980-02-07
AU4857379A (en) 1980-01-10
ES482117A1 (es) 1980-04-01
FI792009A (fi) 1980-01-04
NL7905079A (nl) 1980-01-07
PT69860A (fr) 1979-08-01
GB2027018A (en) 1980-02-13
YU160479A (en) 1983-02-28
US4304915A (en) 1981-12-08
SU826954A3 (ru) 1981-04-30
IL57708A0 (en) 1979-11-30

Similar Documents

Publication Publication Date Title
LU81453A1 (fr) Nouveaux derives de l'indole,leur preparation et leur application comme medicaments
CA1088939A (fr) Medicaments derives de l'indole
EP0581939B1 (de) N-sulfonyl-2-oxoindol-derivate mit einer affinität für die vasopressin und/oder ocytocin rezeptoren
LU79761A1 (fr) Procede de preparation de nouveaux composes de phtalazine et de composition pharmaceutique les contenant
EP0370901A1 (de) Zentralnervensystem wirksame Chromanderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
FR2531707A1 (fr) Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
FR2701708A1 (fr) Dérivés de 2-amido-4-phénylthiazoles polysubstitués, procédé de préparation, composition pharmaceutique et utilisation de ces dérivés pour la préparation d'un médicament.
LU80458A1 (fr) Nouveaux derives de phtalazine,leur procede de production,et composition pharmaceutique les contenant
EP0429344A1 (de) Pyridazin-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
FR2495153A1 (fr) Nouvelles dibenzazepines, leur preparation et leur application comme medicaments
EP1214313B1 (de) Heteroaryloxypropanolamine als beta3-adrenergischer rezeptor-agonisten
EP0498718B1 (de) Verwendung von 4-(3-trifluormethylphenyl)-1,2,3,6-Tetrahydropyridinderivaten als freie Radikalfänger
EP0620221A1 (de) 5-Acylamino-1,2,4-Thiadiazole als cholecystokin Antagonisten oder Agonisten
CA1095047A (fr) Procede de preparation de nouveaux derives du 1,4- benzodioxane
EP0004494B1 (de) 1,3-Dihydro-3-(1-(2-(2,3-dihydro-1,4-benzodioxin-2-yl)2-hydroxy-äthyl)piperidin-4-yl)2H-indol-2-on Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel und diese enthaltende pharmazeutische Zubereitungen
EP0114850B1 (de) Substituierte 2,5-diamino 1,4-diazole, verfahren zu ihrer herstellung, und diese enthaltende farmazeutische zusammenstellungen
FR2758329A1 (fr) Derives d'imidazole-4-butane boronique, leur preparation et leur utilisation en therapeutique
EP0382618B1 (de) Aminoalkoxyphenyl-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Zusammensetzungen
EP0647639A1 (de) Heteroarylpiperidinen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutischen Zusammenstellungen
EP0427606A1 (de) 4-Amidino-Chroman und 4-Amidino-Pyrano(3,2-c)pyridinderivate, Verfahren zur Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
FR2543952A1 (fr) Composes hydrocarbones heterocycliques appartenant aux series indoliques et leur application pharmacologique
EP1266896A1 (de) Lineare oder zyklische Harnstoffe, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
FR2485530A1 (fr) Nouveaux derives du dibenz(cd,f)indole, leur preparation et leur application comme medicaments
CH620678A5 (en) Process for the preparation of a derivative of piperidine
FR2592882A2 (fr) Nouveaux amides substitues, leur preparation et les medicaments qui les contiennent