LU80937A1 - Nouveaux amides derives d'acides carboxyliques-5 pyrimidiniques,leur preparation et leur application en therapeutique - Google Patents

Nouveaux amides derives d'acides carboxyliques-5 pyrimidiniques,leur preparation et leur application en therapeutique

Info

Publication number
LU80937A1
LU80937A1 LU80937A LU80937A LU80937A1 LU 80937 A1 LU80937 A1 LU 80937A1 LU 80937 A LU80937 A LU 80937A LU 80937 A LU80937 A LU 80937A LU 80937 A1 LU80937 A1 LU 80937A1
Authority
LU
Luxembourg
Prior art keywords
pyrimidinic
therapeutics
carboxylic
acids
preparation
Prior art date
Application number
LU80937A
Other languages
English (en)
Inventor
T Imbert
J Ancher
B Bucher
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7804921A external-priority patent/FR2417506A1/fr
Priority claimed from FR7902286A external-priority patent/FR2457286A2/fr
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of LU80937A1 publication Critical patent/LU80937A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/38—One sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
LU80937A 1978-02-21 1979-02-19 Nouveaux amides derives d'acides carboxyliques-5 pyrimidiniques,leur preparation et leur application en therapeutique LU80937A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7804921A FR2417506A1 (fr) 1978-02-21 1978-02-21 Nouveaux amides derives d'acides carboxyliques-5 pyrimidiniques utiles notamment dans le traitement des troubles du psychisme
FR7902286A FR2457286A2 (fr) 1979-01-30 1979-01-30 Nouveaux amides derives d'acides carboxyliques-5 pyrimidiniques, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
LU80937A1 true LU80937A1 (fr) 1979-10-29

Family

ID=26220449

Family Applications (1)

Application Number Title Priority Date Filing Date
LU80937A LU80937A1 (fr) 1978-02-21 1979-02-19 Nouveaux amides derives d'acides carboxyliques-5 pyrimidiniques,leur preparation et leur application en therapeutique

Country Status (13)

Country Link
US (1) US4250178A (fr)
JP (1) JPS54130585A (fr)
AU (1) AU526298B2 (fr)
CA (1) CA1096868A (fr)
CH (1) CH639078A5 (fr)
DE (1) DE2906461A1 (fr)
ES (1) ES477852A1 (fr)
GB (1) GB2014984B (fr)
GR (1) GR66581B (fr)
IT (1) IT1113438B (fr)
LU (1) LU80937A1 (fr)
NL (1) NL7901333A (fr)
SE (1) SE446450B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112617B1 (fr) * 1982-11-04 1986-12-30 Imperial Chemical Industries Plc Procédé d'extraction de valeurs métalliques et extractants métalliques
US4743605A (en) * 1987-02-24 1988-05-10 Warner-Lambert Company Saturated fatty acid amides as inhibitors of acyl-coa:cholesterol acyltransferase
DE4425143A1 (de) * 1994-07-15 1996-01-18 Basf Ag Substituierte Pyrimidinverbindungen und deren Verwendung
JPH11512399A (ja) * 1995-09-01 1999-10-26 シグナル ファーマシューティカルズ，インコーポレイテッド ピリミジンカルボキサミドおよび関連化合物ならびに炎症状態を処置するための方法
US5811428A (en) * 1995-12-18 1998-09-22 Signal Pharmaceuticals, Inc. Pyrimidine carboxamides and related compounds and methods for treating inflammatory conditions
ATE284684T1 (de) * 1997-10-27 2005-01-15 Sumitomo Pharma Amidderivate zur behandlung neurodegenerativer erkrankungen der netzhaut
US7504396B2 (en) * 2003-06-24 2009-03-17 Amgen Inc. Substituted heterocyclic compounds and methods of use
TW200827346A (en) * 2006-11-03 2008-07-01 Astrazeneca Ab Chemical compounds
TW200836719A (en) * 2007-02-12 2008-09-16 Astrazeneca Ab Chemical compounds
KR20100126306A (ko) * 2008-02-04 2010-12-01 아스트라제네카 아베 4-[4-(2-(아다만틸카르바모일)-5-ｔｅｒｔ-부틸-피라졸-1-일]벤조산의 신규한 결정형
CA2719936A1 (fr) * 2008-04-22 2009-10-29 Astrazeneca Ab Pyrimidine-5-carboxamides substitues
EP3193609A4 (fr) * 2014-09-10 2018-02-28 Epizyme, Inc. Composés de pyrrolidine carboxamide substitués

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2789979A (en) * 1954-09-22 1957-04-23 Searle & Co Basically substituted nu-alkyl-2-amino-4-hydroxy-5-pyrimidine carboxamides and salts thereof

Also Published As

Publication number Publication date
AU526298B2 (en) 1983-01-06
CA1096868A (fr) 1981-03-03
GB2014984B (en) 1982-06-09
JPS54130585A (en) 1979-10-09
GB2014984A (en) 1979-09-05
IT7920206A0 (it) 1979-02-15
SE7901493L (sv) 1979-08-22
NL7901333A (nl) 1979-08-23
AU4439279A (en) 1979-07-19
US4250178A (en) 1981-02-10
GR66581B (fr) 1981-03-27
IT1113438B (it) 1986-01-20
CH639078A5 (fr) 1983-10-31
ES477852A1 (es) 1979-08-01
DE2906461A1 (de) 1979-08-23
SE446450B (sv) 1986-09-15

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