LU503112B1 - Use of invs protein in preparation of medicament for repairing heavy metal-induced testicular injury - Google Patents

Use of invs protein in preparation of medicament for repairing heavy metal-induced testicular injury Download PDF

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Publication number
LU503112B1
LU503112B1 LU503112A LU503112A LU503112B1 LU 503112 B1 LU503112 B1 LU 503112B1 LU 503112 A LU503112 A LU 503112A LU 503112 A LU503112 A LU 503112A LU 503112 B1 LU503112 B1 LU 503112B1
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LU
Luxembourg
Prior art keywords
protein
invs
injury
insdqualifier
insdfeature
Prior art date
Application number
LU503112A
Other languages
German (de)
English (en)
Inventor
Linxi Li
Original Assignee
The Second Affiliated Hospital And Yuying Childrens Hospital Of Wenzhou Medical Univ
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Publication of LU503112B1 publication Critical patent/LU503112B1/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0075Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Immunology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
LU503112A 2021-12-07 2022-11-25 Use of invs protein in preparation of medicament for repairing heavy metal-induced testicular injury LU503112B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202111486020.0A CN114129708B (zh) 2021-12-07 2021-12-07 Invs蛋白在制备修复重金属诱导的睾丸损伤的药物中的应用

Publications (1)

Publication Number Publication Date
LU503112B1 true LU503112B1 (en) 2023-06-07

Family

ID=80385026

Family Applications (1)

Application Number Title Priority Date Filing Date
LU503112A LU503112B1 (en) 2021-12-07 2022-11-25 Use of invs protein in preparation of medicament for repairing heavy metal-induced testicular injury

Country Status (3)

Country Link
CN (1) CN114129708B (zh)
LU (1) LU503112B1 (zh)
ZA (1) ZA202204058B (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL2033032B1 (en) * 2022-07-15 2024-01-25 The Second Affiliated Hospital And Yuying Childrens Hospital Of Wenzhou Medical Univ USE OF Dv13-DshC PEPTIDE FRAGMENT IN PREPARATION OF MEDICAMENT FOR REPAIRING TESTICULAR INJURY

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111494612B (zh) * 2020-05-22 2023-04-25 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 层粘蛋白α2功能区在制备维持或修复血睾屏障功能的药物中的应用
CN111569048B (zh) * 2020-05-22 2023-04-18 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 LamG5肽在制备修复睾丸中支持细胞损伤的药物中的应用
CN112516293A (zh) * 2020-12-02 2021-03-19 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 层粘蛋白α2功能区LamG3/4/5在制备预防避孕药诱导的睾丸损伤的药物中的应用

Also Published As

Publication number Publication date
CN114129708A (zh) 2022-03-04
CN114129708B (zh) 2024-06-07
ZA202204058B (en) 2022-06-29

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Effective date: 20230607