LTIP230A - Crystaline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and medicaments containing these sompounds - Google Patents

Crystaline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and medicaments containing these sompounds

Info

Publication number
LTIP230A
LTIP230A LTIP230A LTIP230A LTIP230A LT IP230 A LTIP230 A LT IP230A LT IP230 A LTIP230 A LT IP230A LT IP230 A LTIP230 A LT IP230A LT IP230 A LTIP230 A LT IP230A
Authority
LT
Lithuania
Prior art keywords
alkylene
fumaric acid
acid salts
sompounds
crystaline
Prior art date
Application number
LTIP230A
Other languages
English (en)
Inventor
Uwe Schoen
Walter Heitmann
Uwe Maetzel
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of LTIP230A publication Critical patent/LTIP230A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/15—Fumaric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
LTIP230A 1991-12-03 1992-11-17 Crystaline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and medicaments containing these sompounds LTIP230A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4139763A DE4139763A1 (de) 1991-12-03 1991-12-03 Kristalline fumarsaure salze von 9,9-alkylen-3,7-diazabicyclononan-verbindungen und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
LTIP230A true LTIP230A (en) 1994-05-15

Family

ID=6446125

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP230A LTIP230A (en) 1991-12-03 1992-11-17 Crystaline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and medicaments containing these sompounds

Country Status (25)

Country Link
US (1) US5324732A (de)
EP (1) EP0550383B1 (de)
JP (1) JP3180848B2 (de)
KR (1) KR100252389B1 (de)
CN (1) CN1040758C (de)
AT (1) ATE124411T1 (de)
AU (1) AU652869B2 (de)
CA (1) CA2084489C (de)
CZ (1) CZ281930B6 (de)
DE (2) DE4139763A1 (de)
DK (1) DK0550383T3 (de)
DZ (1) DZ1636A1 (de)
ES (1) ES2073900T3 (de)
FI (1) FI100053B (de)
HK (1) HK1006568A1 (de)
HU (3) HU9203698D0 (de)
IL (1) IL103819A (de)
LT (1) LTIP230A (de)
MX (1) MX9206988A (de)
NO (1) NO300687B1 (de)
NZ (1) NZ245227A (de)
PH (1) PH31114A (de)
SK (1) SK279519B6 (de)
TW (1) TW274084B (de)
ZA (1) ZA928863B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4421324A1 (de) * 1994-06-17 1995-12-21 Kali Chemie Pharma Gmbh Neue 3,7-Diazabicyclo [3,3,1] nonan-Verbindungen enthaltende Arzneimittel
CA2426666A1 (en) * 2000-09-29 2002-04-04 Solvay Pharmaceuticals B.V. Ion-strength independent sustained release pharmaceutical formulation
TW200418468A (en) * 2002-11-18 2004-10-01 Solvay Pharm Gmbh Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events
AU2004260624A1 (en) * 2003-07-21 2005-02-10 Solvay Pharmaceuticals Gmbh Use of 3,7-diazabicyclo`3, 3,1 !nonane compounds for the treatment and/or prophylaxis of anti-arrhythmic events in male human patients
US20050054667A1 (en) * 2003-07-21 2005-03-10 Solvay Pharmaceuticals Gmbh Method of treating or inhibiting anti-arrhythmic events in male human patients
WO2005030207A1 (en) * 2003-09-26 2005-04-07 Solvay Pharmaceuticals Gmbh Use of 3, 7-diazabicyclo (3.3.1) nonane compounds for the treatment of brugada syndrome

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2551283C3 (de) * 1975-11-14 1981-02-19 Hokuriku Pharmaceutical Co., Ltd., Katsuyama, Fukui (Japan) Monofumarsäuresalz von 3-Pyridylmethylnikotinat und Verfahren zu seiner Herstellung
DE2658558A1 (de) * 1976-12-23 1978-06-29 Bayer Ag Diazabicyclo(3,3,1)nonane, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
PT88381B (pt) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline
DE4019080A1 (de) * 1990-06-15 1991-12-19 Kali Chemie Pharma Gmbh Neue 3,7-diazabicycolo (3,3,1)nonan-verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
KR930012772A (ko) 1993-07-21
US5324732A (en) 1994-06-28
DE59202726D1 (de) 1995-08-03
HU213672B (en) 1997-09-29
CZ332292A3 (en) 1993-08-11
ES2073900T3 (es) 1995-08-16
NZ245227A (en) 1994-06-27
NO924647D0 (no) 1992-12-02
CN1072931A (zh) 1993-06-09
EP0550383A1 (de) 1993-07-07
DK0550383T3 (da) 1995-08-28
NO300687B1 (no) 1997-07-07
CA2084489A1 (en) 1993-06-04
ZA928863B (en) 1993-05-13
AU2981592A (en) 1993-06-10
JPH05247040A (ja) 1993-09-24
FI925482A0 (fi) 1992-12-02
KR100252389B1 (ko) 2000-05-01
SK332292A3 (en) 1998-12-02
HUT63417A (en) 1993-08-30
HK1006568A1 (en) 1999-03-05
CA2084489C (en) 2002-10-08
MX9206988A (es) 1993-06-01
TW274084B (de) 1996-04-11
PH31114A (en) 1998-02-23
SK279519B6 (sk) 1998-12-02
IL103819A0 (en) 1993-04-04
FI100053B (fi) 1997-09-15
AU652869B2 (en) 1994-09-08
CN1040758C (zh) 1998-11-18
HU9203698D0 (en) 1993-03-29
NO924647L (no) 1993-06-04
EP0550383B1 (de) 1995-06-28
DZ1636A1 (fr) 2002-02-17
JP3180848B2 (ja) 2001-06-25
HU210215A9 (en) 1995-02-28
IL103819A (en) 1996-09-12
CZ281930B6 (cs) 1997-04-16
ATE124411T1 (de) 1995-07-15
DE4139763A1 (de) 1993-06-09
FI925482A (fi) 1993-06-04

Similar Documents

Publication Publication Date Title
ZA925128B (en) Pyrrolidine derivatives,their preparation and medicaments containing them
IL103778A (en) Organic salts of N,N'-diacetyl cystine process for their preparation and pharmaceutical compositions containing them
EP0498471A3 (en) Liposomes comprising a guanidino aminoglycoside
HU896498D0 (en) Process for preparation of low volatility salts
TW289018B (de)
GR3006426T3 (de)
IL89807A (en) Topical preparation containing ofloxacin for treating otopathy
KR970009583B1 (en) Calcium supplements
EP0221728A3 (en) Monosaccharide containing wound healing preparation
LTIP230A (en) Crystaline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and medicaments containing these sompounds
EP0136464A3 (en) Therapeutic compositions for oral use containing stable s-adenosy1-l-methionine salts
AU7253587A (en) Nylon containing calcium salts
IL79933A0 (en) (+)-6-chloro-5,10-dihydro-5-((1-methyl-4-piperidinyl)-acetyl)-11h-dibenzo(b,e)(1,4)diazepin-11-one and its acid addition salts,their preparation and pharmaceutical compositions containing them
IL76394A0 (en) 7-(pyridinyl)-1-alkyl-1,1,4-dihydro-4-oxoquinolinecarboxylic acid derivatives and salts thereof,their preparation and their antibacterial use
EP0468327A3 (en) Oral pharmaceutical compositions containing hirudin
GR3030042T3 (en) Enantiomeric pure cis-2-oxa-5,8-diazabicyclo (4.3.0)nonanes and process for their preparation
IL70007A0 (en) Azepino(1,2-a)pyrimidine derivatives and acid addition salts thereof and pharmaceutical compositions containing same
PH25927A (en) 3,4-dihydroisoquinolinylacetic acid derivatives and pharmaceutical composition containing these compounds
IL76579A0 (en) Octahydroindolo(2,3-a)quinoli-zin-1-yl-alkanecarboxylic acid amides and their acid addition salts,their preparation and pharmaceutical compositions containing them
JPS5770861A (en) N,n'-bis(5-oxo-1-methyl-pyrrolidine-2-yl-acetic acid)-hydrazide, manufacture and medicinal composition
IL76458A0 (en) Polyether ionophore,its preparation and pharmaceutical and veterinary preparations containing it
HU207316B (en) Process for producing octahydro-indolo/2,3-a/quinolyzinepphenyl-sulfonamide derivatives, acid additional salts thereof and pharmaceutical compositions containing them
IL74064A (en) 1,7-disubstituted-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives and antibacterial compositions containing them
GR80342B (en) Baby's feeding bottle

Legal Events

Date Code Title Description
FD9A Withdrawn applications

Free format text: 941021