LT4043B - A novel pharmaceutical for oral administration comprising progesterone and a polyethylene glycol together with an excipient - Google Patents

A novel pharmaceutical for oral administration comprising progesterone and a polyethylene glycol together with an excipient Download PDF

Info

Publication number
LT4043B
LT4043B LT96-010A LT96010A LT4043B LT 4043 B LT4043 B LT 4043B LT 96010 A LT96010 A LT 96010A LT 4043 B LT4043 B LT 4043B
Authority
LT
Lithuania
Prior art keywords
progesterone
starch
pharmaceutical composition
estradiol
composition according
Prior art date
Application number
LT96-010A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT96010A (da
Inventor
Karen Susanne Gram
Annelise Jensen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of LT96010A publication Critical patent/LT96010A/xx
Publication of LT4043B publication Critical patent/LT4043B/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
LT96-010A 1993-08-20 1996-02-15 A novel pharmaceutical for oral administration comprising progesterone and a polyethylene glycol together with an excipient LT4043B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK93950A DK95093D0 (da) 1993-08-20 1993-08-20 Farmaceutisk formulering indeholdende et hormon

Publications (2)

Publication Number Publication Date
LT96010A LT96010A (da) 1996-06-25
LT4043B true LT4043B (en) 1996-09-25

Family

ID=8099329

Family Applications (1)

Application Number Title Priority Date Filing Date
LT96-010A LT4043B (en) 1993-08-20 1996-02-15 A novel pharmaceutical for oral administration comprising progesterone and a polyethylene glycol together with an excipient

Country Status (17)

Country Link
EP (1) EP0789560A1 (da)
JP (1) JPH09501682A (da)
KR (1) KR960703570A (da)
CN (1) CN1132478A (da)
AU (1) AU7530594A (da)
BR (1) BR9407306A (da)
CA (1) CA2169840A1 (da)
CZ (1) CZ42596A3 (da)
DK (1) DK95093D0 (da)
FI (1) FI960749A7 (da)
HU (1) HUT74167A (da)
LT (1) LT4043B (da)
NO (1) NO960653D0 (da)
NZ (1) NZ271617A (da)
PL (1) PL313113A1 (da)
SK (1) SK19396A3 (da)
WO (1) WO1995005807A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2772617B1 (fr) * 1997-12-19 2001-03-09 Besins Iscovesco Lab Comprime de progesterone et son procede de preparation
FR2775599B1 (fr) 1998-03-09 2001-08-17 Besins Iscovesco Lab Composition pharmaceutique a base de progesterone naturelle de synthese et d'oestradiol et son procede de preparation
GB2339114B (en) * 1998-06-30 2003-03-05 Ericsson Telefon Ab L M Secure messaging in mobile telephones
IL127129A (en) * 1998-11-18 2004-06-01 Ferring Bv Method for preparation of progesterone tablets for vaginal delivery and tablets so prepared
EP1598069B1 (en) * 1999-08-31 2009-04-22 Bayer Schering Pharma Aktiengesellschaft Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive
US6544553B1 (en) * 1999-12-28 2003-04-08 Watson Pharmaceuticals, Inc. Dosage forms and methods for oral delivery of progesterone
FI20002768L (fi) * 2000-12-18 2002-06-19 Licentia Oy Enteropäällysteisiä lääkekoostumuksia ja niiden valmistus
WO2003077923A1 (en) * 2002-03-14 2003-09-25 Watson Pharmaceuticals, Inc. Progesterone oral drug delivery system
MXPA05011626A (es) * 2003-04-29 2006-01-23 Akzo Nobel Nv Procedimiento de soldificacion con antisolvente.
DK1874278T3 (da) 2005-04-28 2009-09-28 Wyeth Corp Sammensætninger indeholdende mikroniseret tanaproget
DE202007019049U1 (de) * 2007-11-05 2010-05-12 Bayer Schering Pharma Aktiengesellschaft Verwendung eines Gestagens in Kombination mit einem Estrogen zur Prophylaxe der Laktoseintoleranz bei der oralen Kontrazeption
US20110312928A1 (en) * 2010-06-18 2011-12-22 Lipocine Inc. Progesterone Containing Oral Dosage Forms and Related Methods
US9375437B2 (en) 2010-06-18 2016-06-28 Lipocine Inc. Progesterone containing oral dosage forms and kits
US8951996B2 (en) 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
BR112014012444B1 (pt) * 2011-11-23 2021-12-14 Therapeuticsmd, Inc Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
MX2017016823A (es) 2015-06-22 2018-03-12 Lipocine Inc Composiciones orales que contienen éster de 17- hydroxiprogesterona y métodos relacionados.
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196188A (en) 1976-11-30 1980-04-01 Besins Jean Louis A Orally administrable form of progesterone
GB2091552A (en) 1980-09-09 1982-08-04 Carnrick G W Ltd Use of progesterone for the treatment of post-menopausal women
US5084277A (en) 1988-08-30 1992-01-28 Greco John C Vaginal progesterone tablet
US5116619A (en) 1988-08-30 1992-05-26 Lee Roy Morgan Vaginal progesterone tablet

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862311A (en) * 1971-04-12 1975-01-21 Ciba Geigy Corp Novel method of enhancing progestational endometrial proliferation with progesterone
US4963540A (en) * 1986-04-16 1990-10-16 Maxson Wayne S Method for treatment of premenstrual syndrome
AU5157590A (en) * 1989-02-06 1990-08-24 Abbott Laboratories Pharmaceutical compositions for oral administration
US5223268A (en) * 1991-05-16 1993-06-29 Sterling Drug, Inc. Low solubility drug-coated bead compositions

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196188A (en) 1976-11-30 1980-04-01 Besins Jean Louis A Orally administrable form of progesterone
GB2091552A (en) 1980-09-09 1982-08-04 Carnrick G W Ltd Use of progesterone for the treatment of post-menopausal women
US5084277A (en) 1988-08-30 1992-01-28 Greco John C Vaginal progesterone tablet
US5116619A (en) 1988-08-30 1992-05-26 Lee Roy Morgan Vaginal progesterone tablet

Also Published As

Publication number Publication date
AU7530594A (en) 1995-03-21
CZ42596A3 (en) 1996-06-12
BR9407306A (pt) 1996-10-08
WO1995005807A1 (en) 1995-03-02
DK95093D0 (da) 1993-08-20
HU9600376D0 (en) 1996-04-29
FI960749A0 (fi) 1996-02-19
EP0789560A1 (en) 1997-08-20
PL313113A1 (en) 1996-06-10
FI960749L (fi) 1996-02-19
NO960653L (no) 1996-02-19
CN1132478A (zh) 1996-10-02
KR960703570A (ko) 1996-08-31
FI960749A7 (fi) 1996-02-19
NZ271617A (en) 1996-11-26
JPH09501682A (ja) 1997-02-18
SK19396A3 (en) 1997-03-05
CA2169840A1 (en) 1995-03-02
LT96010A (da) 1996-06-25
NO960653D0 (no) 1996-02-19
HUT74167A (en) 1996-11-28

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MM9A Lapsed patents

Effective date: 19980819