LT3449939T - Farmacinė kompozicija, skirta vėžio metastazės slopinimui, apimanti, kaip veiklųjį ingredientą, antikūną, kuris specifiškai rišasi prie epidermio augimo faktoriaus receptoriaus - Google Patents
Farmacinė kompozicija, skirta vėžio metastazės slopinimui, apimanti, kaip veiklųjį ingredientą, antikūną, kuris specifiškai rišasi prie epidermio augimo faktoriaus receptoriausInfo
- Publication number
- LT3449939T LT3449939T LTEPPCT/KR2016/004418T LTKR2016004418T LT3449939T LT 3449939 T LT3449939 T LT 3449939T LT KR2016004418 T LTKR2016004418 T LT KR2016004418T LT 3449939 T LT3449939 T LT 3449939T
- Authority
- LT
- Lithuania
- Prior art keywords
- antibody
- cancer
- pharmaceutical composition
- active ingredient
- growth factor
- Prior art date
Links
- 102000001301 EGF receptor Human genes 0.000 title 1
- 108060006698 EGF receptor Proteins 0.000 title 1
- 206010027476 Metastases Diseases 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 230000009401 metastasis Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3046—Stomach, Intestines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/KR2016/004418 WO2017188472A1 (ko) | 2016-04-27 | 2016-04-27 | 표피 성장 인자 수용체에 특이적으로 결합하는 항체를 유효성분으로 포함하는 암의 전이 억제용 약학 조성물 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3449939T true LT3449939T (lt) | 2022-05-25 |
Family
ID=60159801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEPPCT/KR2016/004418T LT3449939T (lt) | 2016-04-27 | 2016-04-27 | Farmacinė kompozicija, skirta vėžio metastazės slopinimui, apimanti, kaip veiklųjį ingredientą, antikūną, kuris specifiškai rišasi prie epidermio augimo faktoriaus receptoriaus |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11198733B2 (lt) |
| EP (1) | EP3449939B1 (lt) |
| JP (1) | JP6701382B2 (lt) |
| KR (1) | KR102128556B1 (lt) |
| CN (1) | CN109195627B (lt) |
| DK (1) | DK3449939T3 (lt) |
| ES (1) | ES2912903T3 (lt) |
| HR (1) | HRP20220576T1 (lt) |
| HU (1) | HUE058745T2 (lt) |
| LT (1) | LT3449939T (lt) |
| PL (1) | PL3449939T3 (lt) |
| SI (1) | SI3449939T1 (lt) |
| WO (1) | WO2017188472A1 (lt) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7790164B2 (en) | 2006-11-14 | 2010-09-07 | Van Andel Research Institute | Fragments of antibodies to epidermal growth factor receptor and methods of their use |
| KR101108642B1 (ko) * | 2009-09-29 | 2012-02-09 | 주식회사 녹십자 | 표피 성장 인자 수용체에 특이적으로 결합하는 항체 |
| AU2011248088B2 (en) * | 2010-05-04 | 2015-06-25 | Merrimack Pharmaceuticals, Inc. | Antibodies against epidermal growth factor receptor (EGFR) and uses thereof |
| KR20130083090A (ko) * | 2012-01-10 | 2013-07-22 | 강원대학교산학협력단 | 암 세포의 ｅｇｆｒ에 특이적으로 결합하는 항체 및 이의 용도 |
| NZ630020A (en) | 2012-03-08 | 2016-08-26 | Halozyme Inc | Conditionally active anti-epidermal growth factor receptor antibodies and methods of use thereof |
| JP6441792B2 (ja) * | 2012-05-17 | 2018-12-19 | ソレント・セラピューティクス・インコーポレイテッドＳｏｒｒｅｎｔｏ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | Ｅｇｆｒに結合する抗原結合蛋白質 |
| US20150147309A1 (en) | 2012-06-06 | 2015-05-28 | Fondazione Telethon | Allosteric chaperones and uses thereof |
| CA2908819A1 (en) * | 2013-04-22 | 2014-10-30 | Glycotope Gmbh | Anti-cancer treatments with anti-egfr antibodies having a low fucosylation |
-
2016
- 2016-04-27 SI SI201631511T patent/SI3449939T1/sl unknown
- 2016-04-27 HR HRP20220576TT patent/HRP20220576T1/hr unknown
- 2016-04-27 WO PCT/KR2016/004418 patent/WO2017188472A1/ko active Application Filing
- 2016-04-27 LT LTEPPCT/KR2016/004418T patent/LT3449939T/lt unknown
- 2016-04-27 EP EP16900546.9A patent/EP3449939B1/en active Active
- 2016-04-27 CN CN201680086176.0A patent/CN109195627B/zh active Active
- 2016-04-27 JP JP2018556298A patent/JP6701382B2/ja active Active
- 2016-04-27 HU HUE16900546A patent/HUE058745T2/hu unknown
- 2016-04-27 PL PL16900546T patent/PL3449939T3/pl unknown
- 2016-04-27 KR KR1020187031020A patent/KR102128556B1/ko active IP Right Grant
- 2016-04-27 US US16/096,988 patent/US11198733B2/en active Active
- 2016-04-27 DK DK16900546.9T patent/DK3449939T3/da active
- 2016-04-27 ES ES16900546T patent/ES2912903T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK3449939T3 (da) | 2022-05-02 |
| JP6701382B2 (ja) | 2020-05-27 |
| CN109195627A (zh) | 2019-01-11 |
| CN109195627B (zh) | 2022-09-09 |
| US20190119388A1 (en) | 2019-04-25 |
| JP2019514909A (ja) | 2019-06-06 |
| ES2912903T3 (es) | 2022-05-30 |
| US11198733B2 (en) | 2021-12-14 |
| EP3449939A1 (en) | 2019-03-06 |
| EP3449939B1 (en) | 2022-03-30 |
| WO2017188472A1 (ko) | 2017-11-02 |
| KR20180137502A (ko) | 2018-12-27 |
| HUE058745T2 (hu) | 2022-09-28 |
| EP3449939A4 (en) | 2019-12-18 |
| KR102128556B1 (ko) | 2020-06-30 |
| HRP20220576T1 (hr) | 2022-06-10 |
| PL3449939T3 (pl) | 2022-06-20 |
| SI3449939T1 (sl) | 2022-06-30 |
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