LT3421601T - In vitro susintetintos ssrnr gamyba ir panaudojimas įvedimui į žinduolių ląsteles biologinio arba biocheminio poveikio sukėlimui - Google Patents

In vitro susintetintos ssrnr gamyba ir panaudojimas įvedimui į žinduolių ląsteles biologinio arba biocheminio poveikio sukėlimui

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Publication number
LT3421601T
LT3421601T LTEP18170777.9T LT18170777T LT3421601T LT 3421601 T LT3421601 T LT 3421601T LT 18170777 T LT18170777 T LT 18170777T LT 3421601 T LT3421601 T LT 3421601T
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LT
Lithuania
Prior art keywords
vitro
induce
biological
introducing
making
Prior art date
Application number
LTEP18170777.9T
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English (en)
Inventor
Judith Meis
Anthony D. PERSON
Cynthia S. Chin
Jerome Jendrisak
Gary A. Dahl
Original Assignee
Cellscript, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellscript, Llc filed Critical Cellscript, Llc
Publication of LT3421601T publication Critical patent/LT3421601T/lt

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A61K48/0066—Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
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    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
    • A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
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LTEP18170777.9T 2011-12-30 2012-12-31 In vitro susintetintos ssrnr gamyba ir panaudojimas įvedimui į žinduolių ląsteles biologinio arba biocheminio poveikio sukėlimui LT3421601T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161582050P 2011-12-30 2011-12-30
US201161582080P 2011-12-30 2011-12-30
US201261651738P 2012-05-25 2012-05-25

Publications (1)

Publication Number Publication Date
LT3421601T true LT3421601T (lt) 2020-01-10

Family

ID=47559751

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP18170777.9T LT3421601T (lt) 2011-12-30 2012-12-31 In vitro susintetintos ssrnr gamyba ir panaudojimas įvedimui į žinduolių ląsteles biologinio arba biocheminio poveikio sukėlimui
LTEP16186283.4T LT3144389T (lt) 2011-12-30 2012-12-31 In vitro susintetintos viengrandės rnr gavimas ir panaudojimas įvedimui į žinduolio ląsteles, siekiant sužadinti biologinį arba biocheminį poveikį

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP16186283.4T LT3144389T (lt) 2011-12-30 2012-12-31 In vitro susintetintos viengrandės rnr gavimas ir panaudojimas įvedimui į žinduolio ląsteles, siekiant sužadinti biologinį arba biocheminį poveikį

Country Status (13)

Country Link
US (3) US10201620B2 (lt)
EP (5) EP3421601B1 (lt)
AU (3) AU2012362113B2 (lt)
CA (1) CA2862377A1 (lt)
DK (3) DK3421601T3 (lt)
ES (2) ES2770314T3 (lt)
HK (1) HK1203559A1 (lt)
HR (1) HRP20200251T1 (lt)
HU (1) HUE047947T2 (lt)
LT (2) LT3421601T (lt)
PL (2) PL3421601T3 (lt)
SI (1) SI3421601T1 (lt)
WO (1) WO2013102203A1 (lt)

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RU2019143431A (ru) 2012-11-01 2020-04-28 Фэктор Байосайенс Инк. Способы и продукты для экспрессии белков в клетках
CA2890529C (en) 2012-11-09 2020-07-28 Biontech Ag Method for modification of cellular rna expression comprising interferon (ifn) receptors and signalling
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HUE042640T2 (hu) 2013-03-14 2019-07-29 Translate Bio Inc CFTR-mRNS-készítmények, valamint kapcsolódó eljárások és alkalmazások
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