LT3250610T - Fcrn antikūnai ir jų panaudojimo būdai - Google Patents

Fcrn antikūnai ir jų panaudojimo būdai

Info

Publication number
LT3250610T
LT3250610T LTEPPCT/US2016/015720T LT16015720T LT3250610T LT 3250610 T LT3250610 T LT 3250610T LT 16015720 T LT16015720 T LT 16015720T LT 3250610 T LT3250610 T LT 3250610T
Authority
LT
Lithuania
Prior art keywords
fcrn antibodies
fcrn
antibodies
Prior art date
Application number
LTEPPCT/US2016/015720T
Other languages
English (en)
Lithuanian (lt)
Inventor
Marilyn Kehry
David King
Leona Ling
James MEADOR III
Sucharita Roy
Anthony Manning
Original Assignee
Momenta Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Momenta Pharmaceuticals, Inc. filed Critical Momenta Pharmaceuticals, Inc.
Publication of LT3250610T publication Critical patent/LT3250610T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
LTEPPCT/US2016/015720T 2015-01-30 2016-01-29 Fcrn antikūnai ir jų panaudojimo būdai LT3250610T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562110071P 2015-01-30 2015-01-30
US201562258082P 2015-11-20 2015-11-20
PCT/US2016/015720 WO2016123521A2 (en) 2015-01-30 2016-01-29 Fcrn antibodies and methods of use thereof

Publications (1)

Publication Number Publication Date
LT3250610T true LT3250610T (lt) 2023-09-25

Family

ID=56544538

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/US2016/015720T LT3250610T (lt) 2015-01-30 2016-01-29 Fcrn antikūnai ir jų panaudojimo būdai

Country Status (21)

Country Link
US (3) US10676526B2 (enExample)
EP (2) EP4286011A3 (enExample)
JP (2) JP6853178B2 (enExample)
KR (3) KR20250052465A (enExample)
CN (13) CN113384693B (enExample)
AU (2) AU2016211280B2 (enExample)
DK (1) DK3250610T3 (enExample)
ES (1) ES2962824T3 (enExample)
FI (1) FI3250610T3 (enExample)
HR (1) HRP20231399T1 (enExample)
HU (1) HUE063778T2 (enExample)
IL (1) IL252837B (enExample)
LT (1) LT3250610T (enExample)
NZ (1) NZ772383A (enExample)
PL (1) PL3250610T3 (enExample)
PT (1) PT3250610T (enExample)
RS (1) RS64768B1 (enExample)
SG (2) SG10202007232WA (enExample)
SI (1) SI3250610T1 (enExample)
SM (1) SMT202300365T1 (enExample)
WO (1) WO2016123521A2 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016014810B1 (pt) 2013-12-24 2023-12-26 Argenx Bvba Antagonistas de fcrn e métodos de uso
EP3155013B1 (en) * 2014-06-12 2019-03-27 F. Hoffmann-La Roche AG Method for selecting antibodies with modified fcrn interaction
HRP20231399T1 (hr) * 2015-01-30 2024-02-16 Momenta Pharmaceuticals, Inc. Fcrn antitijela i načini njihove uporabe
KR20240151878A (ko) 2016-07-29 2024-10-18 모멘타 파머슈티컬스 인코포레이티드 FcRn 항체 및 이의 사용 방법
BR112019026694A2 (pt) * 2017-06-15 2020-06-23 UCB Biopharma SRL Método para o tratamento da trombocitopenia imune
AU2018380979B2 (en) 2017-12-08 2023-07-20 argenx BV Use of FcRn antagonists for treatment of generalized myasthenia gravis
WO2019118791A1 (en) * 2017-12-13 2019-06-20 Momenta Pharmaceuticals, Inc. Fcrn antibodies and methods of use thereof
SG11202011849VA (en) 2018-06-08 2020-12-30 Argenx Bvba Compositions and methods for treating immune thrombocytopenia
JOP20210013A1 (ar) * 2018-07-20 2021-01-19 Momenta Pharmaceuticals Inc تركيبات جسم مضاد fcrn
EA202190335A1 (ru) * 2018-07-20 2021-06-11 Момента Фармасьютикалз, Инк. Композиции антител против fcrn и способы их применения
BR112021007092A2 (pt) 2018-10-16 2021-08-03 UCB Biopharma SRL método para o tratamento de miastenia grave
JP7565951B2 (ja) 2019-06-07 2024-10-11 アルジェニクス ビーブイ 皮下投与に好適なＦｃＲｎインヒビターの医薬製剤
CA3148826A1 (en) * 2019-08-01 2021-02-04 Janssen Biotech, Inc. Fcrn antibodies and methods of use thereof
TW202132346A (zh) * 2019-11-19 2021-09-01 瑞士商依牧諾萬科學有限公司 使用抗-fcrn抗體治療溫抗體型自體免疫性溶血性貧血之方法
EP4087875B1 (en) 2020-01-08 2024-08-28 Argenx BV Antagonists of human neonatal fc receptor (fcrn) for treating pemphigus disorders
AU2021376364A1 (en) * 2020-11-06 2023-06-22 Momenta Pharmaceuticals, Inc. Fcrn antibodies and methods of use thereof
CN114410643B (zh) * 2021-02-02 2024-08-02 百奥赛图(北京)医药科技股份有限公司 FcRn基因人源化的非人动物及其构建方法和应用
JP7755725B2 (ja) * 2021-08-13 2025-10-16 ジャンスー バイオジェッテイ バイオテクノロジー カンパニー リミテッド Ｆｃｒｎを特異的に認識する抗体およびその使用
WO2023030501A1 (zh) * 2021-09-03 2023-03-09 舒泰神（北京）生物制药股份有限公司 特异性识别FcRn的抗体及其应用
KR20250018382A (ko) 2022-05-30 2025-02-05 한올바이오파마주식회사 안정성이 향상된 항-FcRn 항체 또는 이의 항원 결합 단편
JP2025518971A (ja) 2022-06-15 2025-06-19 アルジェニクス ビーブイ ｐＨ依存性ＨＳＡ結合分子及び使用方法
CN120693177A (zh) 2023-02-04 2025-09-23 动量制药公司 用于治疗胎儿和新生儿溶血性疾病的组合物和方法
TW202527982A (zh) 2023-09-11 2025-07-16 美商默門塔醫藥公司 Fcrn抗體之醫藥組成物
WO2025099576A1 (en) 2023-11-06 2025-05-15 Momenta Pharmaceuticals, Inc. Compositions and methods for treating rheumatoid arthritis
WO2025163617A1 (en) 2024-02-04 2025-08-07 Momenta Pharmaceuticals, Inc. Compositions and methods for treating sjögren's disease
WO2025186787A1 (en) 2024-03-08 2025-09-12 Momenta Pharmaceuticals, Inc. Compositions and methods for treating fetal and neonatal alloimmune thrombocytopenia

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101721362B (zh) 2002-02-14 2018-07-03 中外制药株式会社 包含抗体的溶液制剂
US7662928B2 (en) 2003-08-08 2010-02-16 The Research Foundation Of State University Of New York Anti-FcRn antibodies for treatment of auto/allo immune conditions
WO2005013912A2 (en) * 2003-08-08 2005-02-17 The Research Foundation Of State University Of Newyork Anti-fcrn antibodies for treatment of auto/allo immune conditions
CN101124245A (zh) * 2003-11-12 2008-02-13 比奥根艾迪克Ma公司 新生儿Fc受体(FcRn)-结合多肽变体、二聚体Fc结合蛋白及其相关方法
US20090110681A1 (en) 2005-03-08 2009-04-30 Pfizer, Inc. Anti-M-CSF Antibody Compositions
WO2007087289A2 (en) 2006-01-25 2007-08-02 The Research Foundation Of State University Of New York Anti-fcrn antibodies for treatement of auto/allo immune conditions
CN101421297A (zh) * 2006-02-17 2009-04-29 森托尼克斯制药有限公司 阻断lgG对FcRn的结合的肽
CA2644405A1 (en) * 2006-03-13 2007-09-20 Ablynx N.V. Amino acid sequences directed against il-6 and polypeptides comprising the same for the treatment of diseases and disorders associated with il-6-mediated signalling
CN108467431A (zh) * 2008-04-25 2018-08-31 戴埃克斯有限公司 针对fcrn的抗体及其用途
CN102549016B (zh) * 2009-06-30 2015-05-06 研究发展基金会 免疫球蛋白fc多肽
PH12013502378A1 (en) * 2011-06-02 2014-01-06 Dyax Corp Fc RECEPTOR BINDING PROTEINS
GB201208370D0 (en) 2012-05-14 2012-06-27 Ucb Pharma Sa Antibodies
US20130323242A1 (en) 2012-06-01 2013-12-05 Ophthotech Corp. Compositions comprising an anti-pdgf aptamer and a vegf antagonist
US9844594B2 (en) 2012-12-18 2017-12-19 Merck Sharp & Dohme Corp. Liquid formulations for an anti-TNF α antibody
EP3719122A1 (en) 2013-05-02 2020-10-07 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
KR101815265B1 (ko) 2013-06-20 2018-01-04 한올바이오파마주식회사 FcRn 특이적 인간 항체 및 이를 포함하는 자가면역 질환 치료용 조성물
HRP20231399T1 (hr) 2015-01-30 2024-02-16 Momenta Pharmaceuticals, Inc. Fcrn antitijela i načini njihove uporabe
DK3268391T3 (da) 2015-03-09 2021-09-13 Argenx Bvba Fremgangsmåder til reduktion af serumniveauer af Fc-indeholdende midler ved anvendelse af FcRn-antagonister
CA3022547A1 (en) 2015-05-12 2016-11-17 Syntimmune, Inc. Humanized affinity matured anti-fcrn antibodies
KR20240151878A (ko) 2016-07-29 2024-10-18 모멘타 파머슈티컬스 인코포레이티드 FcRn 항체 및 이의 사용 방법
AU2018380979B2 (en) 2017-12-08 2023-07-20 argenx BV Use of FcRn antagonists for treatment of generalized myasthenia gravis
WO2019118791A1 (en) 2017-12-13 2019-06-20 Momenta Pharmaceuticals, Inc. Fcrn antibodies and methods of use thereof
JOP20210013A1 (ar) 2018-07-20 2021-01-19 Momenta Pharmaceuticals Inc تركيبات جسم مضاد fcrn
EA202190335A1 (ru) 2018-07-20 2021-06-11 Момента Фармасьютикалз, Инк. Композиции антител против fcrn и способы их применения

Also Published As

Publication number Publication date
JP7224382B2 (ja) 2023-02-17
ES2962824T3 (es) 2024-03-21
CN118667015A (zh) 2024-09-20
CN113384693B (zh) 2025-07-04
KR20230007545A (ko) 2023-01-12
AU2016211280B2 (en) 2021-11-25
NZ772383A (en) 2024-11-29
FI3250610T3 (fi) 2023-11-01
US20240158508A1 (en) 2024-05-16
PT3250610T (pt) 2023-11-13
CN118667013A (zh) 2024-09-20
CN113384693A (zh) 2021-09-14
SMT202300365T1 (it) 2023-11-13
US10676526B2 (en) 2020-06-09
US20180016334A1 (en) 2018-01-18
EP4286011A2 (en) 2023-12-06
SG10202007232WA (en) 2020-09-29
HRP20231399T1 (hr) 2024-02-16
AU2022201145A1 (en) 2022-03-17
DK3250610T3 (da) 2023-10-30
US11732047B2 (en) 2023-08-22
CN118638229A (zh) 2024-09-13
EP3250610A4 (en) 2018-08-22
HUE063778T2 (hu) 2024-01-28
CN107567460A (zh) 2018-01-09
SG11201705475QA (en) 2017-08-30
KR20170109020A (ko) 2017-09-27
US20200299382A1 (en) 2020-09-24
NZ733097A (en) 2024-07-05
EP3250610A2 (en) 2017-12-06
EP4286011A3 (en) 2024-02-14
JP2021061854A (ja) 2021-04-22
WO2016123521A3 (en) 2016-09-22
CN107567460B (zh) 2021-04-23
CN118638230A (zh) 2024-09-13
IL252837B (en) 2021-10-31
SI3250610T1 (sl) 2023-11-30
AU2016211280A1 (en) 2017-07-13
CN118667011A (zh) 2024-09-20
CN118667012A (zh) 2024-09-20
JP2018504907A (ja) 2018-02-22
BR112017015287A2 (pt) 2018-01-16
EP3250610B1 (en) 2023-08-09
WO2016123521A2 (en) 2016-08-04
KR102483016B1 (ko) 2023-01-03
CN118652337A (zh) 2024-09-17
CN118667010A (zh) 2024-09-20
AU2022201145B2 (en) 2024-11-14
JP6853178B2 (ja) 2021-03-31
RS64768B1 (sr) 2023-11-30
CN118562003A (zh) 2024-08-30
CA2972822A1 (en) 2016-08-04
IL252837A0 (en) 2017-08-31
PL3250610T3 (pl) 2024-01-29
CN118667009A (zh) 2024-09-20
KR102792441B1 (ko) 2025-04-08
CN118667014A (zh) 2024-09-20
KR20250052465A (ko) 2025-04-18

Similar Documents

Publication Publication Date Title
IL283965A (en) Antibodies against cd73 and uses thereof
LT3250610T (lt) Fcrn antikūnai ir jų panaudojimo būdai
LT3280441T (lt) Anti-sortilino antikūnai ir jų naudojimo būdai
LT3491025T (lt) Fcrn antikūnai ir jų panaudojimo būdai
IL263452A (en) Anti-ige antibodies
LT3215532T (lt) Anti-tim3 antikūnai ir jų naudojimo būdai
LT3347379T (lt) Anti-tigit antikūnai, anti-pvrig antikūnai ir jų kombinacijos
LT3303394T (lt) Anti-ctla-4 antikūnai ir jų naudojimo būdai
LT3274370T (lt) Antikūnai prieš ceacam6 ir jų panaudojimas
LT3443009T (lt) Anti-tim-3 antikūnai ir kompozicijos
LT3333191T (lt) Anti-c10orf54 antikūnai ir jų panaudojimas
LT3353212T (lt) Optimizuoti anti-cd3 bispecifiniai antikūnai ir jų naudojimas
LT3148579T (lt) Anti-gitr antikūnai ir jų panaudojimo būdai
LT3317284T (lt) Benzoksazepino oksazolidinono junginiai ir jų naudojimo būdai
DK3344654T3 (da) Anti-lag-3-antistoffer
DK3126388T3 (da) Anti-EGFRvIII-antistoffer og anvendelser deraf
LT3653221T (lt) Anti-pvrig antikūnai ir naudojimo būdai
DK3350218T3 (da) Polyomavirus-neutraliserende antistoffer
HUE060878T2 (hu) Anti-transztiretin antitestek
IL262776A (en) Humanized anti-il-1r3 antibodies
LT3532499T (lt) Antikūnai prieš il-33 ir jų panaudojimas
DK3250593T3 (da) Anti-transthyretin-antistoffer
EP3835319C0 (en) Humanized Anti-ACTH Antibodies and Their Use
IL256099A (en) Antibody
IL247590A0 (en) Bispecific antibodies and their uses