LT3211B - Novel derivatives of hydroxyanthranilic acid, methods for their preparation and the use thereof - Google Patents

Novel derivatives of hydroxyanthranilic acid, methods for their preparation and the use thereof Download PDF

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Publication number
LT3211B
LT3211B LTIP1882A LTIP1882A LT3211B LT 3211 B LT3211 B LT 3211B LT IP1882 A LTIP1882 A LT IP1882A LT IP1882 A LTIP1882 A LT IP1882A LT 3211 B LT3211 B LT 3211B
Authority
LT
Lithuania
Prior art keywords
alkyl
oso
different
same
formula
Prior art date
Application number
LTIP1882A
Other languages
English (en)
Lithuanian (lt)
Inventor
Susanna Karin Maria Bjoerk
Barry Keith Carpenter
Kristina Birgitta Gotthammar
Mats Torbjoern Linderberg
Per Johan Luthman
Kerstin Margareta Irma Persson
Robert Schwarcz
Original Assignee
Astra Ab
Cornell Res Foundation Inc
Univ Maryland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab, Cornell Res Foundation Inc, Univ Maryland filed Critical Astra Ab
Publication of LTIP1882A publication Critical patent/LTIP1882A/xx
Publication of LT3211B publication Critical patent/LT3211B/lt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C205/60—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms in ortho-position to the carboxyl group, e.g. nitro-salicylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/64—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Use Of Switch Circuits For Exchanges And Methods Of Control Of Multiplex Exchanges (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
LTIP1882A 1993-02-26 1994-02-23 Novel derivatives of hydroxyanthranilic acid, methods for their preparation and the use thereof LT3211B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9300658A SE9300658D0 (sv) 1993-02-26 1993-02-26 New compounds

Publications (2)

Publication Number Publication Date
LTIP1882A LTIP1882A (en) 1994-09-25
LT3211B true LT3211B (en) 1995-04-25

Family

ID=20389054

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1882A LT3211B (en) 1993-02-26 1994-02-23 Novel derivatives of hydroxyanthranilic acid, methods for their preparation and the use thereof

Country Status (22)

Country Link
US (2) US5523475A (ja)
EP (1) EP0686145B1 (ja)
JP (1) JPH08509468A (ja)
CN (1) CN1121345A (ja)
AT (1) ATE189206T1 (ja)
AU (1) AU6160094A (ja)
BR (1) BR9406091A (ja)
CZ (1) CZ216895A3 (ja)
DE (1) DE69422800D1 (ja)
EE (1) EE9400386A (ja)
FI (1) FI954017A0 (ja)
HU (1) HUT72744A (ja)
IL (1) IL108753A0 (ja)
IS (1) IS4134A (ja)
LT (1) LT3211B (ja)
MX (1) MX9401456A (ja)
NO (1) NO953333D0 (ja)
NZ (1) NZ262219A (ja)
PL (1) PL310399A1 (ja)
SE (1) SE9300658D0 (ja)
SK (1) SK97095A3 (ja)
WO (1) WO1994019316A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2788768B1 (fr) 1999-01-21 2001-02-16 Oreal Nouveaux 2-acylaminophenols cationiques, leur utilisation a titre de coupleur pour la teinture d'oxydation, compositions les comprenant, et procedes de teinture
FR2788691B1 (fr) 1999-01-21 2002-06-14 Oreal Compositions pour la teinture d'oxydation des fibres keratiniques comprenant un coupleur cationique, nouveaux coupleurs cationiques, leur utilisation pour la teinture d'oxydation, et procedes de teinture
JP5641582B2 (ja) * 2009-05-21 2014-12-17 静岡県公立大学法人 芳香族フッ素化合物の製造方法および新規化合物
US11867487B1 (en) 2021-03-03 2024-01-09 Wach Llc System and method for aeronautical stabilization

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1847518A (en) * 1930-01-23 1932-03-01 Gen Aniline Works Inc Omicron-amino-p-cresol-carboxylic-acid and process of making same
US2652332A (en) * 1951-07-19 1953-09-15 Harold S Olcott Stabilization of lipoidal substances
US2843599A (en) * 1954-09-28 1958-07-15 Bayer Ag Process for the production of phthalocyanine dyestuffs
US2894984A (en) * 1958-05-15 1959-07-14 Pennsalt Chemicals Corp 4-trifluoromethyl salicylic acids and their preparation
US3211610A (en) * 1961-09-29 1965-10-12 Merck & Co Inc Benzoic acid ester derivatives for treating coccidiosis and method of using same
US3657436A (en) * 1970-02-09 1972-04-18 Hoffmann La Roche Method of treating col-sk virus infections
US4119609A (en) * 1977-03-28 1978-10-10 Shell Oil Company Curable epoxy-carboxylic acid adducts
DE2751136A1 (de) * 1977-11-16 1979-05-23 Bayer Ag Verfahren zur herstellung aromatischer aminohydroxyverbindungen
US5514676A (en) * 1984-03-19 1996-05-07 The Rockefeller University Amino-benzoic acids and derivatives, and methods of use
DE3608726A1 (de) * 1986-03-15 1987-09-17 Hoechst Ag Verwendung aminosubstituierter benzoesaeuren als heilmittel gegen diarrhoe und arzneimittel auf basis dieser verbindungen
US5025036A (en) * 1987-10-01 1991-06-18 Hoffmann-La Roche Inc. Catechol carboxylic acids
JP2684276B2 (ja) * 1991-11-27 1997-12-03 富士写真フイルム株式会社 ハロゲン化銀カラー写真感光材料
US5512596A (en) * 1994-09-02 1996-04-30 Gilead Sciences, Inc. Aromatic compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
C.J. PARLI P. KRIETER, B. SCHEDT: "Metabolism of 6-chlorotryptophan to 4-chloroanthranilic acid: A potent inhibitor of 3-hydroxyanthranlilic acid oxidase", ARCH. BIOCHEM AND BIOPHYS, pages 161 - 166
M.P. HEYES B. HUTTO S MARKEY: "4-cloro-3hydroxyanthranilate inhibits brain 3-hydroxxxynathrinilate oxidase", NEUROCHEM, 13,1988, pages 405 - 408

Also Published As

Publication number Publication date
CZ216895A3 (en) 1996-04-17
MX9401456A (es) 1994-08-31
NO953333L (no) 1995-08-24
CN1121345A (zh) 1996-04-24
EP0686145B1 (en) 2000-01-26
EP0686145A1 (en) 1995-12-13
EE9400386A (et) 1996-06-17
PL310399A1 (en) 1995-12-11
LTIP1882A (en) 1994-09-25
JPH08509468A (ja) 1996-10-08
BR9406091A (pt) 1995-12-12
ATE189206T1 (de) 2000-02-15
NZ262219A (en) 1997-04-24
NO953333D0 (no) 1995-08-24
IS4134A (is) 1994-08-27
WO1994019316A1 (en) 1994-09-01
HU9502490D0 (en) 1995-10-30
HUT72744A (en) 1996-05-28
US5883129A (en) 1999-03-16
US5523475A (en) 1996-06-04
FI954017A (fi) 1995-08-25
AU6160094A (en) 1994-09-14
SE9300658D0 (sv) 1993-02-26
IL108753A0 (en) 1994-06-24
FI954017A0 (fi) 1995-08-25
SK97095A3 (en) 1996-10-02
DE69422800D1 (de) 2000-03-02

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Effective date: 19970223