LT3010962T - Polilaktido-poliglikolido mikrodalelių, turinčių sigmoidinio atpalaidavimo profilį, gavimas - Google Patents
Polilaktido-poliglikolido mikrodalelių, turinčių sigmoidinio atpalaidavimo profilį, gavimasInfo
- Publication number
- LT3010962T LT3010962T LTEP14733524.4T LT14733524T LT3010962T LT 3010962 T LT3010962 T LT 3010962T LT 14733524 T LT14733524 T LT 14733524T LT 3010962 T LT3010962 T LT 3010962T
- Authority
- LT
- Lithuania
- Prior art keywords
- polylactide
- preparation
- release profile
- sigmoidal release
- polyglycolide microparticles
- Prior art date
Links
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 title 1
- 229920000954 Polyglycolide Polymers 0.000 title 1
- 239000011859 microparticle Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
- C08J3/14—Powdering or granulating by precipitation from solutions
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2300/00—Characterised by the use of unspecified polymers
- C08J2300/16—Biodegradable polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
- C08J2367/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2013001821 | 2013-06-20 | ||
| PCT/EP2014/001652 WO2014202214A1 (en) | 2013-06-20 | 2014-06-18 | Preparation of polylactide-polyglycolide microparticles having a sigmoidal release profile |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3010962T true LT3010962T (lt) | 2017-09-25 |
Family
ID=51022802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP14733524.4T LT3010962T (lt) | 2013-06-20 | 2014-06-18 | Polilaktido-poliglikolido mikrodalelių, turinčių sigmoidinio atpalaidavimo profilį, gavimas |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9943484B2 (https=) |
| JP (1) | JP6464154B2 (https=) |
| CN (1) | CN105308101B (https=) |
| AU (1) | AU2014283692B2 (https=) |
| CA (1) | CA2916301C (https=) |
| DK (1) | DK3010962T4 (https=) |
| ES (1) | ES2640486T5 (https=) |
| FI (1) | FI3010962T4 (https=) |
| HU (1) | HUE036141T2 (https=) |
| LT (1) | LT3010962T (https=) |
| PT (1) | PT3010962T (https=) |
| RU (1) | RU2658004C2 (https=) |
| SA (1) | SA515370296B1 (https=) |
| WO (1) | WO2014202214A1 (https=) |
| ZA (1) | ZA201509354B (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2956538C (en) | 2014-07-30 | 2023-01-03 | Merck Patent Gmbh | Directly compressible composition comprising microcrystalline cellulose |
| JP2016102093A (ja) * | 2014-11-28 | 2016-06-02 | ニプロ株式会社 | 塩基性の求核化合物を含有するマイクロカプセルの製造方法 |
| CA2998504C (en) | 2015-09-21 | 2023-06-20 | Teva Pharmaceuticals International Gmbh | Sustained release olanzapine formulations |
| WO2018172850A1 (en) | 2017-03-20 | 2018-09-27 | Teva Pharmaceuticals International Gmbh | Sustained release olanzapine formulaitons |
| KR102047983B1 (ko) | 2017-11-30 | 2019-11-22 | 주식회사 지투지바이오 | 안전성 및 저장 안정성이 향상된 생분해성 미립구의 제조방법 |
| GR1009870B (el) * | 2019-07-09 | 2020-11-12 | Φαρματεν Α.Β.Ε.Ε. | Φαρμακευτικο σκευασμα που περιλαμβανει ενα ατυπο αντιψυχωσικο φαρμακο και μεθοδος παρασκευης αυτου |
| KR102908216B1 (ko) * | 2019-12-31 | 2026-01-06 | 광저우 디치 파마슈티컬스 컴퍼니 리미티드 | 3차 아민 약학 조성물 및 이의 산업화 배치 제조 방법 |
| EP4125823A1 (en) | 2020-03-30 | 2023-02-08 | Biological E Limited | Risperidone microspheres, process for their prepartion and uses thereof |
| KR102259589B1 (ko) * | 2020-11-30 | 2021-06-02 | (주)인벤티지랩 | 미소구체 제조 시스템 및 미소구체 제조 방법 |
| US20240100012A1 (en) | 2021-01-18 | 2024-03-28 | Mark Hasleton | Pharmaceutical dosage form |
| US11992559B2 (en) * | 2021-02-24 | 2024-05-28 | Oakwood Laboratories, Llc | Microsphere formulations comprising lurasidone and methods for making and using the same |
| CA3227324A1 (en) | 2021-07-06 | 2023-01-12 | Mark Hasleton | Treatment of serotonin reuptake inhibitor withdrawal syndrome |
| GR1010327B (el) * | 2021-10-06 | 2022-10-17 | Φαρματεν Α.Β.Ε.Ε., | Παρατεταμενης αποδεσμευσης ενεσιμο φαρμακευτικο σκευασμα λεβοθυροξινης και μεθοδος παρασκευης αυτου |
| WO2025135778A1 (ko) * | 2023-12-18 | 2025-06-26 | 주식회사 포스테라헬스사이언스 | 약물의 특성에 따른 활성형 미립자의 제조 방법, 이의 제조 방법으로 제조된 활성형 미립자 및 상기 활성형 미립자를 이용한 약물을 포함하는 장기 지속 제형의 제조 방법 |
| WO2025207396A1 (en) * | 2024-03-27 | 2025-10-02 | Avidence Therapeutics, Inc. | Microsphere-based injectable rofecoxib formulation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478564A (en) * | 1990-02-22 | 1995-12-26 | Teva Pharmaceutical Industries, Ltd. | Preparation of microparticles for controlled release of water-soluble substances |
| US5288496A (en) * | 1990-05-15 | 1994-02-22 | Stolle Research & Development Corporation | Growth promoters for animals |
| WO1997026869A1 (en) * | 1996-01-24 | 1997-07-31 | United States Government Represented By The Secretary Of The Army | Novel 'burst-free' sustained release poly-(lactide/glycolide) microspheres |
| US5792477A (en) * | 1996-05-07 | 1998-08-11 | Alkermes Controlled Therapeutics, Inc. Ii | Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent |
| US6194006B1 (en) * | 1998-12-30 | 2001-02-27 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of microparticles having a selected release profile |
| US6264987B1 (en) | 2000-05-19 | 2001-07-24 | Alkermes Controlled Therapeutics Inc. Ii | Method for preparing microparticles having a selected polymer molecular weight |
| US7690026B2 (en) * | 2005-08-22 | 2010-03-30 | Microsoft Corporation | Distributed single sign-on service |
-
2014
- 2014-06-18 RU RU2016101418A patent/RU2658004C2/ru active
- 2014-06-18 HU HUE14733524A patent/HUE036141T2/hu unknown
- 2014-06-18 ES ES14733524T patent/ES2640486T5/es active Active
- 2014-06-18 FI FIEP14733524.4T patent/FI3010962T4/fi active
- 2014-06-18 CA CA2916301A patent/CA2916301C/en active Active
- 2014-06-18 PT PT147335244T patent/PT3010962T/pt unknown
- 2014-06-18 JP JP2016520312A patent/JP6464154B2/ja active Active
- 2014-06-18 LT LTEP14733524.4T patent/LT3010962T/lt unknown
- 2014-06-18 WO PCT/EP2014/001652 patent/WO2014202214A1/en not_active Ceased
- 2014-06-18 CN CN201480034979.2A patent/CN105308101B/zh active Active
- 2014-06-18 AU AU2014283692A patent/AU2014283692B2/en active Active
- 2014-06-18 DK DK14733524.4T patent/DK3010962T4/da active
- 2014-06-18 US US14/898,415 patent/US9943484B2/en active Active
-
2015
- 2015-12-17 SA SA515370296A patent/SA515370296B1/ar unknown
- 2015-12-23 ZA ZA2015/09354A patent/ZA201509354B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK3010962T4 (da) | 2023-04-17 |
| WO2014202214A1 (en) | 2014-12-24 |
| CN105308101A (zh) | 2016-02-03 |
| CA2916301A1 (en) | 2014-12-24 |
| US9943484B2 (en) | 2018-04-17 |
| AU2014283692A1 (en) | 2016-01-21 |
| JP2017507895A (ja) | 2017-03-23 |
| ES2640486T3 (es) | 2017-11-03 |
| JP6464154B2 (ja) | 2019-02-06 |
| DK3010962T3 (en) | 2017-10-23 |
| ES2640486T5 (es) | 2023-04-28 |
| PT3010962T (pt) | 2017-09-05 |
| RU2016101418A (ru) | 2017-07-25 |
| HUE036141T2 (hu) | 2018-06-28 |
| CN105308101B (zh) | 2018-10-23 |
| RU2658004C2 (ru) | 2018-06-19 |
| FI3010962T4 (fi) | 2023-05-04 |
| CA2916301C (en) | 2020-01-07 |
| ZA201509354B (en) | 2017-07-26 |
| AU2014283692B2 (en) | 2017-04-27 |
| SA515370296B1 (ar) | 2017-10-12 |
| US20160143851A1 (en) | 2016-05-26 |
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