LT2993231T - Rekombinantinio baltymo raiškai skirtas bakterijų kamienas, turintis proteazės negaminantį degp su išlaikytų šaperoniniu aktyvumu ir išveiklintus tsp ir ptr genus - Google Patents

Rekombinantinio baltymo raiškai skirtas bakterijų kamienas, turintis proteazės negaminantį degp su išlaikytų šaperoniniu aktyvumu ir išveiklintus tsp ir ptr genus

Info

Publication number
LT2993231T
LT2993231T LTEP15182886.0T LT15182886T LT2993231T LT 2993231 T LT2993231 T LT 2993231T LT 15182886 T LT15182886 T LT 15182886T LT 2993231 T LT2993231 T LT 2993231T
Authority
LT
Lithuania
Prior art keywords
saperonic
suspensioned
ptr
tsp
campaign
Prior art date
Application number
LTEP15182886.0T
Other languages
English (en)
Lithuanian (lt)
Inventor
Mark Ellis
David Paul Humphreys
Original Assignee
Ucb Biopharma Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0916822.0A external-priority patent/GB0916822D0/en
Priority claimed from GB0916821A external-priority patent/GB0916821D0/en
Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl
Publication of LT2993231T publication Critical patent/LT2993231T/lt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
LTEP15182886.0T 2009-09-24 2010-09-23 Rekombinantinio baltymo raiškai skirtas bakterijų kamienas, turintis proteazės negaminantį degp su išlaikytų šaperoniniu aktyvumu ir išveiklintus tsp ir ptr genus LT2993231T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0916822.0A GB0916822D0 (en) 2009-09-24 2009-09-24 Bacterial host strain
GB0916821A GB0916821D0 (en) 2009-09-24 2009-09-24 Bacterial host strain

Publications (1)

Publication Number Publication Date
LT2993231T true LT2993231T (lt) 2018-11-12

Family

ID=43003459

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP15182886.0T LT2993231T (lt) 2009-09-24 2010-09-23 Rekombinantinio baltymo raiškai skirtas bakterijų kamienas, turintis proteazės negaminantį degp su išlaikytų šaperoniniu aktyvumu ir išveiklintus tsp ir ptr genus

Country Status (21)

Country Link
US (3) US9109216B2 (forum.php)
EP (2) EP2993231B1 (forum.php)
JP (2) JP6132551B2 (forum.php)
KR (1) KR101758942B1 (forum.php)
CN (1) CN102575241B (forum.php)
AU (2) AU2010299640B2 (forum.php)
BR (1) BR112012006670B8 (forum.php)
CA (1) CA2774692C (forum.php)
CY (1) CY1120947T1 (forum.php)
DK (1) DK2993231T3 (forum.php)
ES (1) ES2692811T3 (forum.php)
HR (1) HRP20181482T1 (forum.php)
HU (1) HUE040306T2 (forum.php)
IN (1) IN2012DN02401A (forum.php)
LT (1) LT2993231T (forum.php)
PL (1) PL2993231T3 (forum.php)
PT (1) PT2993231T (forum.php)
SG (1) SG10201606462WA (forum.php)
SI (1) SI2993231T1 (forum.php)
SM (1) SMT201800549T1 (forum.php)
WO (1) WO2011036454A1 (forum.php)

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CN117965503B (zh) * 2024-02-02 2024-08-09 南京迪诺薇华生物科技有限公司 一种蛋白酶突变体及其在洗护肤品、化妆品中的应用

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Also Published As

Publication number Publication date
HUE040306T2 (hu) 2019-03-28
EP2993231A3 (en) 2016-05-11
IN2012DN02401A (forum.php) 2015-08-21
JP2016116517A (ja) 2016-06-30
CN102575241B (zh) 2016-02-24
PL2993231T3 (pl) 2019-01-31
SMT201800549T1 (it) 2018-11-09
PT2993231T (pt) 2018-11-12
CY1120947T1 (el) 2019-12-11
ES2692811T3 (es) 2018-12-05
EP2480661A1 (en) 2012-08-01
DK2993231T3 (en) 2018-10-22
HK1172650A1 (zh) 2013-04-26
EP2993231B1 (en) 2018-08-01
AU2010299640B2 (en) 2016-02-25
BR112012006670A2 (pt) 2015-09-08
US20160200810A1 (en) 2016-07-14
US9550973B2 (en) 2017-01-24
EP2993231A2 (en) 2016-03-09
BR112012006670B8 (pt) 2022-03-03
BR112012006670B1 (pt) 2021-08-03
KR20120083435A (ko) 2012-07-25
CN102575241A (zh) 2012-07-11
WO2011036454A1 (en) 2011-03-31
SG10201606462WA (en) 2016-09-29
JP2013505714A (ja) 2013-02-21
CA2774692A1 (en) 2011-03-31
US9109216B2 (en) 2015-08-18
US20120258492A1 (en) 2012-10-11
US20150344840A1 (en) 2015-12-03
KR101758942B1 (ko) 2017-07-17
HRP20181482T1 (hr) 2018-11-02
CA2774692C (en) 2017-12-19
JP6132551B2 (ja) 2017-05-24
SI2993231T1 (sl) 2018-10-30
AU2010299640A1 (en) 2012-04-12
US9315770B2 (en) 2016-04-19
AU2016201536A1 (en) 2016-03-24

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