SG10201606462WA - Bacterial host strain - Google Patents

Bacterial host strain

Info

Publication number
SG10201606462WA
SG10201606462WA SG10201606462WA SG10201606462WA SG10201606462WA SG 10201606462W A SG10201606462W A SG 10201606462WA SG 10201606462W A SG10201606462W A SG 10201606462WA SG 10201606462W A SG10201606462W A SG 10201606462WA SG 10201606462W A SG10201606462W A SG 10201606462WA
Authority
SG
Singapore
Prior art keywords
bacterial host
host strain
strain
bacterial
host
Prior art date
Application number
SG10201606462WA
Inventor
Mark Ellis
David Paul Humphreys
Original Assignee
Ucb Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0916821A external-priority patent/GB0916821D0/en
Priority claimed from GBGB0916822.0A external-priority patent/GB0916822D0/en
Application filed by Ucb Pharma Sa filed Critical Ucb Pharma Sa
Publication of SG10201606462WA publication Critical patent/SG10201606462WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
SG10201606462WA 2009-09-24 2010-09-23 Bacterial host strain SG10201606462WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0916821A GB0916821D0 (en) 2009-09-24 2009-09-24 Bacterial host strain
GBGB0916822.0A GB0916822D0 (en) 2009-09-24 2009-09-24 Bacterial host strain

Publications (1)

Publication Number Publication Date
SG10201606462WA true SG10201606462WA (en) 2016-09-29

Family

ID=43003459

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201606462WA SG10201606462WA (en) 2009-09-24 2010-09-23 Bacterial host strain

Country Status (21)

Country Link
US (3) US9109216B2 (en)
EP (2) EP2480661A1 (en)
JP (2) JP6132551B2 (en)
KR (1) KR101758942B1 (en)
CN (1) CN102575241B (en)
AU (2) AU2010299640B2 (en)
BR (1) BR112012006670B8 (en)
CA (1) CA2774692C (en)
CY (1) CY1120947T1 (en)
DK (1) DK2993231T3 (en)
ES (1) ES2692811T3 (en)
HK (1) HK1172650A1 (en)
HR (1) HRP20181482T1 (en)
HU (1) HUE040306T2 (en)
IN (1) IN2012DN02401A (en)
LT (1) LT2993231T (en)
PL (1) PL2993231T3 (en)
PT (1) PT2993231T (en)
SG (1) SG10201606462WA (en)
SI (1) SI2993231T1 (en)
WO (1) WO2011036454A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010299640B2 (en) * 2009-09-24 2016-02-25 Ucb Pharma S.A. Bacterial host strain
GB201000590D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial host strain
GB201000591D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial hoist strain
GB201000587D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial hoist strain
GB201012599D0 (en) 2010-07-27 2010-09-08 Ucb Pharma Sa Process for purifying proteins
EP3339325A1 (en) * 2011-07-13 2018-06-27 UCB Biopharma SPRL Bacterial host strain expressing recombinant dsbc
GB201208367D0 (en) 2012-05-14 2012-06-27 Ucb Pharma Sa Biological product
JP2022525775A (en) 2019-03-18 2022-05-19 バイオ-ラッド エービーディー セロテック ゲーエムベーハー Protection of SpyTag-containing periplasmic fusion proteins from protease TSP and OMPT degradation
CN110616181A (en) * 2019-09-27 2019-12-27 北京理工大学 Engineering strain based on escherichia coli transformation

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US6083715A (en) 1997-06-09 2000-07-04 Board Of Regents, The University Of Texas System Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells
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US6306619B1 (en) * 1999-06-29 2001-10-23 Washington University DegP periplasmic protease a new anti-infective target and an in vitro assay for DegP protease function
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EP1314037A2 (en) 2000-09-01 2003-05-28 Biogen, Inc. Methods of designing and producing compounds having improved binding affinity for cd154 or other trimeric proteins
AU8867501A (en) 2000-09-01 2002-03-13 Biogen Inc Co-crystal structure of monoclonal antibody 5c8 and cd154, and use thereof in drug design
US7041479B2 (en) 2000-09-06 2006-05-09 The Board Of Trustess Of The Leland Stanford Junior University Enhanced in vitro synthesis of active proteins containing disulfide bonds
ATE405650T1 (en) 2000-12-14 2008-09-15 Genentech Inc PRODUCTION OF WHOLE ANTIBODIES IN PROKARYONTIC CELLS
US6828121B2 (en) 2000-12-14 2004-12-07 Genentech, Inc. Bacterial host strains
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TWI334439B (en) 2001-08-01 2010-12-11 Centocor Inc Anti-tnf antibodies, compositions, methods and uses
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SI2496601T1 (en) 2009-11-05 2017-09-29 F. Hoffmann-La Roche Ag Methods and composition for secretion of heterologous polypeptides
GB201000587D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial hoist strain
GB201000590D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial host strain
GB201000588D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial host strain
GB201000591D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial hoist strain
GB201001791D0 (en) 2010-02-03 2010-03-24 Ucb Pharma Sa Process for obtaining antibodies
GB201012599D0 (en) 2010-07-27 2010-09-08 Ucb Pharma Sa Process for purifying proteins
EP3339325A1 (en) 2011-07-13 2018-06-27 UCB Biopharma SPRL Bacterial host strain expressing recombinant dsbc
EP2546267A1 (en) 2011-07-13 2013-01-16 UCB Pharma S.A. Bacterial host strain expressing recombinant DsbC
GB201208367D0 (en) 2012-05-14 2012-06-27 Ucb Pharma Sa Biological product

Also Published As

Publication number Publication date
JP6132551B2 (en) 2017-05-24
AU2016201536A1 (en) 2016-03-24
BR112012006670B8 (en) 2022-03-03
CA2774692C (en) 2017-12-19
PT2993231T (en) 2018-11-12
ES2692811T3 (en) 2018-12-05
EP2993231A3 (en) 2016-05-11
EP2480661A1 (en) 2012-08-01
EP2993231A2 (en) 2016-03-09
EP2993231B1 (en) 2018-08-01
AU2010299640B2 (en) 2016-02-25
WO2011036454A1 (en) 2011-03-31
PL2993231T3 (en) 2019-01-31
HUE040306T2 (en) 2019-03-28
KR101758942B1 (en) 2017-07-17
SI2993231T1 (en) 2018-10-30
DK2993231T3 (en) 2018-10-22
KR20120083435A (en) 2012-07-25
US9550973B2 (en) 2017-01-24
HRP20181482T1 (en) 2018-11-02
AU2010299640A1 (en) 2012-04-12
JP2016116517A (en) 2016-06-30
CY1120947T1 (en) 2019-12-11
US9109216B2 (en) 2015-08-18
CN102575241A (en) 2012-07-11
US20120258492A1 (en) 2012-10-11
IN2012DN02401A (en) 2015-08-21
US9315770B2 (en) 2016-04-19
CN102575241B (en) 2016-02-24
CA2774692A1 (en) 2011-03-31
BR112012006670B1 (en) 2021-08-03
US20160200810A1 (en) 2016-07-14
BR112012006670A2 (en) 2015-09-08
JP2013505714A (en) 2013-02-21
US20150344840A1 (en) 2015-12-03
HK1172650A1 (en) 2013-04-26
LT2993231T (en) 2018-11-12

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