LT2860175T - 4,4,7-trifluor-1,2,3,4-tetrahidro-5h-1-benzazepino junginio ir jo sintezei skirto tarpinio junginio gamybos būdas - Google Patents

4,4,7-trifluor-1,2,3,4-tetrahidro-5h-1-benzazepino junginio ir jo sintezei skirto tarpinio junginio gamybos būdas

Info

Publication number
LT2860175T
LT2860175T LTEP13804693.3T LT13804693T LT2860175T LT 2860175 T LT2860175 T LT 2860175T LT 13804693 T LT13804693 T LT 13804693T LT 2860175 T LT2860175 T LT 2860175T
Authority
LT
Lithuania
Prior art keywords
trifluoro
tetrahydro
synthesis
producing
benzazepine compound
Prior art date
Application number
LTEP13804693.3T
Other languages
English (en)
Inventor
Souichirou Kawazoe
Takahiro AKIBA
Kiichi Sato
Akio Miyafuji
Kazuyoshi Obitsu
Junji Itoh
Shun HIRASAWA
Hiroyuki Koshio
Original Assignee
Tacurion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tacurion filed Critical Tacurion
Publication of LT2860175T publication Critical patent/LT2860175T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D301/00Preparation of oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LTEP13804693.3T 2012-06-11 2013-06-11 4,4,7-trifluor-1,2,3,4-tetrahidro-5h-1-benzazepino junginio ir jo sintezei skirto tarpinio junginio gamybos būdas LT2860175T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012131504 2012-06-11
PCT/JP2013/066076 WO2013187406A1 (ja) 2012-06-11 2013-06-11 4,4,7-トリフルオロ-1,2,3,4-テトラヒドロ-5h-1-ベンゾアゼピン化合物の製造方法及びその合成中間体

Publications (1)

Publication Number Publication Date
LT2860175T true LT2860175T (lt) 2018-03-26

Family

ID=49758228

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP13804693.3T LT2860175T (lt) 2012-06-11 2013-06-11 4,4,7-trifluor-1,2,3,4-tetrahidro-5h-1-benzazepino junginio ir jo sintezei skirto tarpinio junginio gamybos būdas

Country Status (15)

Country Link
US (3) US9598373B2 (lt)
EP (1) EP2860175B1 (lt)
JP (2) JPWO2013187406A1 (lt)
CY (1) CY1119983T1 (lt)
DK (1) DK2860175T3 (lt)
ES (1) ES2659180T3 (lt)
HR (1) HRP20180032T8 (lt)
HU (1) HUE035391T2 (lt)
LT (1) LT2860175T (lt)
NO (1) NO2860175T3 (lt)
PL (1) PL2860175T3 (lt)
PT (1) PT2860175T (lt)
RS (1) RS56804B1 (lt)
SI (1) SI2860175T1 (lt)
WO (1) WO2013187406A1 (lt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013367084B2 (en) * 2012-12-26 2017-06-08 Sanwa Kagaku Kenkyusho Co., Ltd. Novel benzazepine derivative and pharmaceutical use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2857760B2 (ja) * 1989-02-17 1999-02-17 第一製薬株式会社 プロポキシニトロベンゼン類の製法
EP0930307B1 (en) * 1996-09-18 2002-12-04 Daiso Co., Ltd. Process for the preparation of glycidyl ethers
KR100632882B1 (ko) * 2001-11-16 2006-10-13 아스텔라스세이야쿠 가부시키가이샤 4, 4-디플루오로-1, 2, 3,4-테트라하이드로-5h-1-벤즈아제핀 유도체 또는 그 염
WO2004096775A1 (ja) * 2003-04-28 2004-11-11 Astellas Pharma Inc. 4,4-ジフルオロ-1,2,3,4-テトラヒドロ-5h-1-ベンゾアゼピン誘導体又はその塩
MXPA06014716A (es) * 2004-06-24 2007-03-12 Lilly Co Eli Compuestos y metodos para el tratamiento de dislipidemia.
JP4765545B2 (ja) * 2004-10-27 2011-09-07 アステラス製薬株式会社 ベンゾアゼピン誘導体を有効成分とする医薬組成物
JP4765546B2 (ja) * 2004-10-27 2011-09-07 アステラス製薬株式会社 ベンゾアゼピン誘導体又はその塩の製造法
KR101312150B1 (ko) * 2008-02-01 2013-09-26 인터디지탈 패튼 홀딩스, 인크 불연속 수신에서 동작하는 wtru에 대한 셀 재선택을 인에이블하기 위한 방법 및 장치

Also Published As

Publication number Publication date
US20150141641A1 (en) 2015-05-21
EP2860175B1 (en) 2017-11-29
PT2860175T (pt) 2018-02-02
WO2013187406A1 (ja) 2013-12-19
CY1119983T1 (el) 2018-12-12
JPWO2013187406A1 (ja) 2016-02-04
US9598373B2 (en) 2017-03-21
HRP20180032T8 (hr) 2018-12-14
HRP20180032T1 (hr) 2018-03-23
EP2860175A4 (en) 2015-12-09
SI2860175T1 (en) 2018-04-30
US10508084B2 (en) 2019-12-17
NO2860175T3 (lt) 2018-04-28
US9951022B2 (en) 2018-04-24
EP2860175A1 (en) 2015-04-15
RS56804B1 (sr) 2018-04-30
JP2019014716A (ja) 2019-01-31
US20170158639A1 (en) 2017-06-08
PL2860175T3 (pl) 2018-07-31
US20190062280A1 (en) 2019-02-28
HUE035391T2 (en) 2018-05-02
DK2860175T3 (da) 2018-01-29
ES2659180T3 (es) 2018-03-14

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