RS56804B1 - Postupak za proizvodnju jedinjenja 4,4,7-trifluoro-1,2,3,4-tetrahidro-5h-1-benzazepina i intermedijer za njegovu sintezu - Google Patents
Postupak za proizvodnju jedinjenja 4,4,7-trifluoro-1,2,3,4-tetrahidro-5h-1-benzazepina i intermedijer za njegovu sintezuInfo
- Publication number
- RS56804B1 RS56804B1 RS20180081A RSP20180081A RS56804B1 RS 56804 B1 RS56804 B1 RS 56804B1 RS 20180081 A RS20180081 A RS 20180081A RS P20180081 A RSP20180081 A RS P20180081A RS 56804 B1 RS56804 B1 RS 56804B1
- Authority
- RS
- Serbia
- Prior art keywords
- trifluoro
- tetrahydro
- synthesis
- producing
- benzazepine compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012131504 | 2012-06-11 | ||
| EP13804693.3A EP2860175B1 (en) | 2012-06-11 | 2013-06-11 | Method for producing 4,4,7-trifluoro-1,2,3,4-tetrahydro-5h-1-benzazepine compound and intermediate for synthesis thereof |
| PCT/JP2013/066076 WO2013187406A1 (ja) | 2012-06-11 | 2013-06-11 | 4,4,7-トリフルオロ-1,2,3,4-テトラヒドロ-5h-1-ベンゾアゼピン化合物の製造方法及びその合成中間体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS56804B1 true RS56804B1 (sr) | 2018-04-30 |
Family
ID=49758228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20180081A RS56804B1 (sr) | 2012-06-11 | 2013-06-11 | Postupak za proizvodnju jedinjenja 4,4,7-trifluoro-1,2,3,4-tetrahidro-5h-1-benzazepina i intermedijer za njegovu sintezu |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US9598373B2 (sr) |
| EP (1) | EP2860175B1 (sr) |
| JP (2) | JPWO2013187406A1 (sr) |
| CY (1) | CY1119983T1 (sr) |
| DK (1) | DK2860175T3 (sr) |
| ES (1) | ES2659180T3 (sr) |
| HR (1) | HRP20180032T8 (sr) |
| HU (1) | HUE035391T2 (sr) |
| LT (1) | LT2860175T (sr) |
| NO (1) | NO2860175T3 (sr) |
| PL (1) | PL2860175T3 (sr) |
| PT (1) | PT2860175T (sr) |
| RS (1) | RS56804B1 (sr) |
| SI (1) | SI2860175T1 (sr) |
| WO (1) | WO2013187406A1 (sr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX362478B (es) * | 2012-12-26 | 2019-01-11 | Sanwa Kagaku Kenkyusho Co | Derivado de benzoazepina novedoso y uso medico del mismo. |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2857760B2 (ja) * | 1989-02-17 | 1999-02-17 | 第一製薬株式会社 | プロポキシニトロベンゼン類の製法 |
| CA2263267C (en) * | 1996-09-18 | 2006-05-02 | Daiso Co., Ltd. | Process for the preparation of glycidyl ethers |
| DE60233251D1 (de) | 2001-11-16 | 2009-09-17 | Astellas Pharma Inc | 4,4-difluor-1,2,3,4-tetrahydro-5h-1-benzazepinderivate und deren salze |
| EP1619185B1 (en) * | 2003-04-28 | 2011-06-15 | Astellas Pharma Inc. | 4,4-difluoro-1,2,3,4-tetrahydro-5h-1-benzazepine derivative or salt thereof |
| US20080269284A1 (en) * | 2004-06-24 | 2008-10-30 | Eli Lilly And Company | Compounds and Methods for Treating Dyslipidemia |
| JP4765545B2 (ja) * | 2004-10-27 | 2011-09-07 | アステラス製薬株式会社 | ベンゾアゼピン誘導体を有効成分とする医薬組成物 |
| JP4765546B2 (ja) * | 2004-10-27 | 2011-09-07 | アステラス製薬株式会社 | ベンゾアゼピン誘導体又はその塩の製造法 |
| CN103634940B (zh) * | 2008-02-01 | 2017-06-06 | 交互数字专利控股公司 | 用于在wtru中执行的drx的方法以及wtru |
-
2013
- 2013-06-11 PL PL13804693T patent/PL2860175T3/pl unknown
- 2013-06-11 US US14/406,568 patent/US9598373B2/en not_active Expired - Fee Related
- 2013-06-11 SI SI201330925T patent/SI2860175T1/en unknown
- 2013-06-11 PT PT138046933T patent/PT2860175T/pt unknown
- 2013-06-11 NO NO13804693A patent/NO2860175T3/no unknown
- 2013-06-11 EP EP13804693.3A patent/EP2860175B1/en active Active
- 2013-06-11 RS RS20180081A patent/RS56804B1/sr unknown
- 2013-06-11 JP JP2014521349A patent/JPWO2013187406A1/ja not_active Ceased
- 2013-06-11 WO PCT/JP2013/066076 patent/WO2013187406A1/ja active Application Filing
- 2013-06-11 DK DK13804693.3T patent/DK2860175T3/da active
- 2013-06-11 HU HUE13804693A patent/HUE035391T2/en unknown
- 2013-06-11 ES ES13804693.3T patent/ES2659180T3/es active Active
- 2013-06-11 LT LTEP13804693.3T patent/LT2860175T/lt unknown
-
2017
- 2017-02-16 US US15/434,678 patent/US9951022B2/en not_active Expired - Fee Related
-
2018
- 2018-01-09 HR HRP20180032TT patent/HRP20180032T8/hr unknown
- 2018-01-24 CY CY20181100092T patent/CY1119983T1/el unknown
- 2018-03-23 US US15/933,804 patent/US10508084B2/en not_active Expired - Fee Related
- 2018-08-15 JP JP2018152818A patent/JP2019014716A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US9598373B2 (en) | 2017-03-21 |
| SI2860175T1 (en) | 2018-04-30 |
| HRP20180032T1 (hr) | 2018-03-23 |
| LT2860175T (lt) | 2018-03-26 |
| US9951022B2 (en) | 2018-04-24 |
| HUE035391T2 (en) | 2018-05-02 |
| US20170158639A1 (en) | 2017-06-08 |
| HRP20180032T8 (hr) | 2018-12-14 |
| JPWO2013187406A1 (ja) | 2016-02-04 |
| DK2860175T3 (da) | 2018-01-29 |
| US20150141641A1 (en) | 2015-05-21 |
| PT2860175T (pt) | 2018-02-02 |
| PL2860175T3 (pl) | 2018-07-31 |
| ES2659180T3 (es) | 2018-03-14 |
| EP2860175A4 (en) | 2015-12-09 |
| EP2860175A1 (en) | 2015-04-15 |
| WO2013187406A1 (ja) | 2013-12-19 |
| US10508084B2 (en) | 2019-12-17 |
| EP2860175B1 (en) | 2017-11-29 |
| CY1119983T1 (el) | 2018-12-12 |
| NO2860175T3 (sr) | 2018-04-28 |
| US20190062280A1 (en) | 2019-02-28 |
| JP2019014716A (ja) | 2019-01-31 |
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