LT2838539T - Estrogeniniai dariniai, skirti naudoti neurologinių sutrikimų gydymui - Google Patents
Estrogeniniai dariniai, skirti naudoti neurologinių sutrikimų gydymuiInfo
- Publication number
- LT2838539T LT2838539T LTEP13714917.5T LT13714917T LT2838539T LT 2838539 T LT2838539 T LT 2838539T LT 13714917 T LT13714917 T LT 13714917T LT 2838539 T LT2838539 T LT 2838539T
- Authority
- LT
- Lithuania
- Prior art keywords
- treatment
- neurological disorders
- estrogenic derivatives
- estrogenic
- derivatives
- Prior art date
Links
- 208000012902 Nervous system disease Diseases 0.000 title 1
- 208000025966 Neurological disease Diseases 0.000 title 1
- 230000001076 estrogenic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12164741.6A EP2653163A1 (en) | 2012-04-19 | 2012-04-19 | Estrogenic components for use in the treatment of neurological disorders |
| PCT/EP2013/057279 WO2013156329A1 (en) | 2012-04-19 | 2013-04-08 | Estrogenic components for use in the treatment of neurological disorders. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2838539T true LT2838539T (lt) | 2017-11-27 |
Family
ID=48050711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP13714917.5T LT2838539T (lt) | 2012-04-19 | 2013-04-08 | Estrogeniniai dariniai, skirti naudoti neurologinių sutrikimų gydymui |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9238035B2 (lt) |
| EP (2) | EP2653163A1 (lt) |
| JP (1) | JP6139662B2 (lt) |
| CN (1) | CN104379148B (lt) |
| AU (1) | AU2013248481B2 (lt) |
| CA (1) | CA2869902C (lt) |
| CY (1) | CY1119603T1 (lt) |
| DK (1) | DK2838539T3 (lt) |
| ES (1) | ES2647111T3 (lt) |
| HR (1) | HRP20171627T1 (lt) |
| HU (1) | HUE034902T2 (lt) |
| LT (1) | LT2838539T (lt) |
| NO (1) | NO2838539T3 (lt) |
| PL (1) | PL2838539T3 (lt) |
| PT (1) | PT2838539T (lt) |
| RS (1) | RS56595B1 (lt) |
| RU (1) | RU2627846C2 (lt) |
| SI (1) | SI2838539T1 (lt) |
| SM (1) | SMT201700531T1 (lt) |
| WO (1) | WO2013156329A1 (lt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012164095A1 (en) | 2011-06-01 | 2012-12-06 | Estetra S.A. | Process for the production of estetrol intermediates |
| AU2012264602B2 (en) | 2011-06-01 | 2017-03-09 | Estetra Srl | Process for the production of estetrol intermediates |
| EP2383279A1 (en) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Process for the preparation of estetrol |
| WO2016187558A2 (en) * | 2015-05-20 | 2016-11-24 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Method to improve neurologic outcomes in temperature managed patients |
| US20160367567A1 (en) | 2015-06-18 | 2016-12-22 | Mithra Pharmaceuticals S.A. | Orodispersible dosage unit containing an estetrol component |
| UA123099C2 (uk) | 2015-06-18 | 2021-02-17 | Естетра Спрл | Диспергована в порожнині рота одиниця дозування, яка містить естетрольний компонент |
| HRP20210668T1 (hr) * | 2015-06-18 | 2021-05-28 | Estetra Sprl | Orodisperzibilna tableta koja sadrži estetrol |
| MD3310346T2 (ro) * | 2015-06-18 | 2021-06-30 | Estetra Sprl | Comprimată orodispersabilă ce conține estetrol |
| CA3178291A1 (en) | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
| CN107260712A (zh) * | 2017-06-22 | 2017-10-20 | 中国人民解放军第三军医大学 | 奥培米芬在制备促进髓鞘形成和再生的药物中的应用 |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| JOP20200260A1 (ar) | 2018-04-19 | 2019-10-19 | Estetra Sprl | مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث |
| HU231240B1 (hu) | 2019-09-03 | 2022-04-28 | Richter Gedeon Nyrt. | Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására |
| CN113243332B (zh) * | 2020-02-07 | 2023-07-28 | 上海市东方医院（同济大学附属东方医院） | 一种广泛脑区神经元树突发育障碍动物模型的制备与应用 |
| TWI893101B (zh) | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
| HUP2400151A1 (hu) | 2024-02-28 | 2025-09-28 | Richter Gedeon Nyrt | Ösztetrol-monohidrát kristályosítási eljárás |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2378898A (en) * | 2001-08-14 | 2003-02-26 | Hunter Fleming Ltd | Prophylactic and therapeutic use of hydroxysteroids |
| WO2003103684A1 (en) * | 2002-06-11 | 2003-12-18 | Pantarhei Bioscience B.V. | Method of treating or preventing immune mediated disorders and pharmaceutical formulation for use therein |
| WO2003103683A1 (en) | 2002-06-11 | 2003-12-18 | Pantarhei Bioscience B.V. | Use of estetrol and analogues for treating or preventing cardiovascular pathologies, in particular atherosclerosis |
| EP3045177A1 (en) * | 2005-09-26 | 2016-07-20 | The Regents of The University of California | Estriol therapy for autoimmune and neurodegenerative diseases and disorders |
| US20090221540A1 (en) * | 2006-01-09 | 2009-09-03 | Pantarhei Bioscience B.V. | Method of Treating An Acute Vascular Disorder |
| ATE537833T1 (de) * | 2007-06-21 | 2012-01-15 | Pantarhei Bioscience Bv | Behandlung des mekoniumaspirationssyndroms mit östrogenen |
| AU2008325211B2 (en) * | 2007-11-06 | 2014-11-13 | Signal Coordinating Therapy, Inc. | Compositions and methods for treating Parkinson's disease and related disorders |
| CN101884638B (zh) * | 2010-07-09 | 2011-11-09 | 中山大学 | 5α-雄甾(烷)-3β,5,6β-三醇在制备神经元保护药物中的应用 |
-
2012
- 2012-04-19 EP EP12164741.6A patent/EP2653163A1/en not_active Withdrawn
-
2013
- 2013-04-08 HU HUE13714917A patent/HUE034902T2/hu unknown
- 2013-04-08 RS RS20171122A patent/RS56595B1/sr unknown
- 2013-04-08 US US14/395,465 patent/US9238035B2/en active Active
- 2013-04-08 HR HRP20171627TT patent/HRP20171627T1/hr unknown
- 2013-04-08 CA CA2869902A patent/CA2869902C/en active Active
- 2013-04-08 AU AU2013248481A patent/AU2013248481B2/en active Active
- 2013-04-08 ES ES13714917.5T patent/ES2647111T3/es active Active
- 2013-04-08 SI SI201330825T patent/SI2838539T1/sl unknown
- 2013-04-08 LT LTEP13714917.5T patent/LT2838539T/lt unknown
- 2013-04-08 EP EP13714917.5A patent/EP2838539B1/en active Active
- 2013-04-08 JP JP2015506173A patent/JP6139662B2/ja active Active
- 2013-04-08 WO PCT/EP2013/057279 patent/WO2013156329A1/en not_active Ceased
- 2013-04-08 NO NO13714917A patent/NO2838539T3/no unknown
- 2013-04-08 PL PL13714917T patent/PL2838539T3/pl unknown
- 2013-04-08 RU RU2014145800A patent/RU2627846C2/ru active
- 2013-04-08 DK DK13714917.5T patent/DK2838539T3/da active
- 2013-04-08 CN CN201380020555.6A patent/CN104379148B/zh active Active
- 2013-04-08 PT PT137149175T patent/PT2838539T/pt unknown
- 2013-04-08 SM SM20170531T patent/SMT201700531T1/it unknown
-
2017
- 2017-11-14 CY CY20171101193T patent/CY1119603T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN104379148A (zh) | 2015-02-25 |
| JP6139662B2 (ja) | 2017-05-31 |
| WO2013156329A1 (en) | 2013-10-24 |
| CA2869902A1 (en) | 2013-10-24 |
| EP2838539B1 (en) | 2017-08-16 |
| SI2838539T1 (sl) | 2017-12-29 |
| HUE034902T2 (hu) | 2018-03-28 |
| RS56595B1 (sr) | 2018-02-28 |
| PT2838539T (pt) | 2017-11-15 |
| CY1119603T1 (el) | 2018-04-04 |
| EP2653163A1 (en) | 2013-10-23 |
| RU2014145800A (ru) | 2016-06-10 |
| AU2013248481B2 (en) | 2017-02-16 |
| HRP20171627T1 (hr) | 2017-12-01 |
| ES2647111T3 (es) | 2017-12-19 |
| AU2013248481A1 (en) | 2014-10-30 |
| PL2838539T3 (pl) | 2018-01-31 |
| RU2627846C2 (ru) | 2017-08-14 |
| JP2015514731A (ja) | 2015-05-21 |
| CN104379148B (zh) | 2017-08-25 |
| SMT201700531T1 (it) | 2018-01-11 |
| US20150133419A1 (en) | 2015-05-14 |
| DK2838539T3 (da) | 2017-11-27 |
| NO2838539T3 (lt) | 2018-01-13 |
| EP2838539A1 (en) | 2015-02-25 |
| CA2869902C (en) | 2019-07-02 |
| US9238035B2 (en) | 2016-01-19 |
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