CN104379148B - 用于治疗神经障碍的雌激素组分 - Google Patents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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Abstract
Description
Claims (5)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12164741.6 | 2012-04-19 | ||
EP12164741.6A EP2653163A1 (en) | 2012-04-19 | 2012-04-19 | Estrogenic components for use in the treatment of neurological disorders |
PCT/EP2013/057279 WO2013156329A1 (en) | 2012-04-19 | 2013-04-08 | Estrogenic components for use in the treatment of neurological disorders. |
Publications (2)
Publication Number | Publication Date |
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CN104379148A CN104379148A (zh) | 2015-02-25 |
CN104379148B true CN104379148B (zh) | 2017-08-25 |
Family
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Family Applications (1)
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CN201380020555.6A Active CN104379148B (zh) | 2012-04-19 | 2013-04-08 | 用于治疗神经障碍的雌激素组分 |
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US (1) | US9238035B2 (zh) |
EP (2) | EP2653163A1 (zh) |
JP (1) | JP6139662B2 (zh) |
CN (1) | CN104379148B (zh) |
AU (1) | AU2013248481B2 (zh) |
CA (1) | CA2869902C (zh) |
CY (1) | CY1119603T1 (zh) |
DK (1) | DK2838539T3 (zh) |
ES (1) | ES2647111T3 (zh) |
HR (1) | HRP20171627T1 (zh) |
HU (1) | HUE034902T2 (zh) |
LT (1) | LT2838539T (zh) |
NO (1) | NO2838539T3 (zh) |
PL (1) | PL2838539T3 (zh) |
PT (1) | PT2838539T (zh) |
RS (1) | RS56595B1 (zh) |
RU (1) | RU2627846C2 (zh) |
SI (1) | SI2838539T1 (zh) |
SM (1) | SMT201700531T1 (zh) |
WO (1) | WO2013156329A1 (zh) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2714710T3 (en) | 2011-06-01 | 2016-06-27 | Estetra Sprl | A process for the preparation of intermediates estetrol |
ES2600703T3 (es) | 2011-06-01 | 2017-02-10 | Estetra S.P.R.L. | Proceso para la producción de intermediarios de estetrol |
EP2383279A1 (en) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Process for the preparation of estetrol |
US11638745B2 (en) * | 2015-05-20 | 2023-05-02 | University of Pittsburgh—Of the Commonwealth Cvctom of Hierher Education | Method to improve neurologic outcomes in temperature managed patients |
LT3310345T (lt) * | 2015-06-18 | 2021-06-25 | Estetra Sprl | Burnoje disperguojama tabletė, turinti estetrolio |
MX384904B (es) | 2015-06-18 | 2025-03-14 | Estetra Sprl | Unidad de dosificacion orodispersable que contiene un componente estetrol. |
HRP20210555T1 (hr) * | 2015-06-18 | 2021-05-14 | Estetra Sprl | Orodisperzibilna tableta koja sadrži estetrol |
NO3106148T3 (zh) | 2015-06-18 | 2018-08-11 | ||
CA3178291A1 (en) | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
CN107260712A (zh) * | 2017-06-22 | 2017-10-20 | 中国人民解放军第三军医大学 | 奥培米芬在制备促进髓鞘形成和再生的药物中的应用 |
TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
JOP20200260A1 (ar) | 2018-04-19 | 2019-10-19 | Estetra Sprl | مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث |
HU231240B1 (hu) | 2019-09-03 | 2022-04-28 | Richter Gedeon Nyrt. | Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására |
CN113243332B (zh) * | 2020-02-07 | 2023-07-28 | 上海市东方医院(同济大学附属东方医院) | 一种广泛脑区神经元树突发育障碍动物模型的制备与应用 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1691947A (zh) * | 2002-06-11 | 2005-11-02 | 潘塔希生物科学股份有限公司 | 治疗或预防免疫介导的疾病的方法以及用于该方法中的药物组合物 |
WO2007038636A2 (en) * | 2005-09-26 | 2007-04-05 | The Regents Of The University Of California | Estriol therapy for autoimmune and neurodegenerataive diseases and disorders |
WO2009061428A1 (en) * | 2007-11-06 | 2009-05-14 | Kline Ellis L | Compositions and methods for treating parkinson's disease and related disorders |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
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GB2378898A (en) * | 2001-08-14 | 2003-02-26 | Hunter Fleming Ltd | Prophylactic and therapeutic use of hydroxysteroids |
AU2003274943A1 (en) | 2002-06-11 | 2003-12-22 | Pantarhei Bioscience B.V. | Use of estetrol and analogues for treating or preventing cardiovascular pathologies, in particular atherosclerosis |
US20090221540A1 (en) * | 2006-01-09 | 2009-09-03 | Pantarhei Bioscience B.V. | Method of Treating An Acute Vascular Disorder |
CA2691654C (en) * | 2007-06-21 | 2016-06-07 | Pantarhei Bioscience B.V. | Treatment of meconium aspiration syndrome with estrogens |
CN101884638B (zh) * | 2010-07-09 | 2011-11-09 | 中山大学 | 5α-雄甾(烷)-3β,5,6β-三醇在制备神经元保护药物中的应用 |
-
2012
- 2012-04-19 EP EP12164741.6A patent/EP2653163A1/en not_active Withdrawn
-
2013
- 2013-04-08 ES ES13714917.5T patent/ES2647111T3/es active Active
- 2013-04-08 NO NO13714917A patent/NO2838539T3/no unknown
- 2013-04-08 CA CA2869902A patent/CA2869902C/en active Active
- 2013-04-08 SM SM20170531T patent/SMT201700531T1/it unknown
- 2013-04-08 WO PCT/EP2013/057279 patent/WO2013156329A1/en active Application Filing
- 2013-04-08 LT LTEP13714917.5T patent/LT2838539T/lt unknown
- 2013-04-08 RS RS20171122A patent/RS56595B1/sr unknown
- 2013-04-08 DK DK13714917.5T patent/DK2838539T3/da active
- 2013-04-08 JP JP2015506173A patent/JP6139662B2/ja active Active
- 2013-04-08 PL PL13714917T patent/PL2838539T3/pl unknown
- 2013-04-08 SI SI201330825T patent/SI2838539T1/sl unknown
- 2013-04-08 EP EP13714917.5A patent/EP2838539B1/en active Active
- 2013-04-08 HR HRP20171627TT patent/HRP20171627T1/hr unknown
- 2013-04-08 RU RU2014145800A patent/RU2627846C2/ru active
- 2013-04-08 CN CN201380020555.6A patent/CN104379148B/zh active Active
- 2013-04-08 AU AU2013248481A patent/AU2013248481B2/en active Active
- 2013-04-08 HU HUE13714917A patent/HUE034902T2/hu unknown
- 2013-04-08 PT PT137149175T patent/PT2838539T/pt unknown
- 2013-04-08 US US14/395,465 patent/US9238035B2/en active Active
-
2017
- 2017-11-14 CY CY20171101193T patent/CY1119603T1/el unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1691947A (zh) * | 2002-06-11 | 2005-11-02 | 潘塔希生物科学股份有限公司 | 治疗或预防免疫介导的疾病的方法以及用于该方法中的药物组合物 |
WO2007038636A2 (en) * | 2005-09-26 | 2007-04-05 | The Regents Of The University Of California | Estriol therapy for autoimmune and neurodegenerataive diseases and disorders |
WO2009061428A1 (en) * | 2007-11-06 | 2009-05-14 | Kline Ellis L | Compositions and methods for treating parkinson's disease and related disorders |
Non-Patent Citations (1)
Title |
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17β-Estradiol protects the neonatal brain from hypoxia–ischemia;Joseph Nuñez et al.;《Experimental Neurology》;20070912;第208卷;第269–276页 * |
Also Published As
Publication number | Publication date |
---|---|
CY1119603T1 (el) | 2018-04-04 |
PT2838539T (pt) | 2017-11-15 |
US20150133419A1 (en) | 2015-05-14 |
HUE034902T2 (hu) | 2018-03-28 |
EP2838539B1 (en) | 2017-08-16 |
EP2838539A1 (en) | 2015-02-25 |
CA2869902A1 (en) | 2013-10-24 |
ES2647111T3 (es) | 2017-12-19 |
RU2014145800A (ru) | 2016-06-10 |
JP6139662B2 (ja) | 2017-05-31 |
PL2838539T3 (pl) | 2018-01-31 |
WO2013156329A1 (en) | 2013-10-24 |
US9238035B2 (en) | 2016-01-19 |
EP2653163A1 (en) | 2013-10-23 |
SI2838539T1 (sl) | 2017-12-29 |
CN104379148A (zh) | 2015-02-25 |
DK2838539T3 (da) | 2017-11-27 |
JP2015514731A (ja) | 2015-05-21 |
SMT201700531T1 (it) | 2018-01-11 |
AU2013248481A1 (en) | 2014-10-30 |
RU2627846C2 (ru) | 2017-08-14 |
AU2013248481B2 (en) | 2017-02-16 |
NO2838539T3 (zh) | 2018-01-13 |
LT2838539T (lt) | 2017-11-27 |
HRP20171627T1 (hr) | 2017-12-01 |
RS56595B1 (sr) | 2018-02-28 |
CA2869902C (en) | 2019-07-02 |
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