DK2838539T3 - Østrogenderivater til anvendelse i behandlingen af neurologiske forstyrrelser - Google Patents

Østrogenderivater til anvendelse i behandlingen af neurologiske forstyrrelser

Info

Publication number
DK2838539T3
DK2838539T3 DK13714917.5T DK13714917T DK2838539T3 DK 2838539 T3 DK2838539 T3 DK 2838539T3 DK 13714917 T DK13714917 T DK 13714917T DK 2838539 T3 DK2838539 T3 DK 2838539T3
Authority
DK
Denmark
Prior art keywords
estrogender
derivatives
treatment
neurological disorders
neurological
Prior art date
Application number
DK13714917.5T
Other languages
English (en)
Inventor
Jean-Michel Foidart
Ekaterine Tskitishvili
Original Assignee
Univ Liege
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Liege filed Critical Univ Liege
Application granted granted Critical
Publication of DK2838539T3 publication Critical patent/DK2838539T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
DK13714917.5T 2012-04-19 2013-04-08 Østrogenderivater til anvendelse i behandlingen af neurologiske forstyrrelser DK2838539T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12164741.6A EP2653163A1 (en) 2012-04-19 2012-04-19 Estrogenic components for use in the treatment of neurological disorders
PCT/EP2013/057279 WO2013156329A1 (en) 2012-04-19 2013-04-08 Estrogenic components for use in the treatment of neurological disorders.

Publications (1)

Publication Number Publication Date
DK2838539T3 true DK2838539T3 (da) 2017-11-27

Family

ID=48050711

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13714917.5T DK2838539T3 (da) 2012-04-19 2013-04-08 Østrogenderivater til anvendelse i behandlingen af neurologiske forstyrrelser

Country Status (19)

Country Link
US (1) US9238035B2 (da)
EP (2) EP2653163A1 (da)
JP (1) JP6139662B2 (da)
CN (1) CN104379148B (da)
AU (1) AU2013248481B2 (da)
CA (1) CA2869902C (da)
CY (1) CY1119603T1 (da)
DK (1) DK2838539T3 (da)
ES (1) ES2647111T3 (da)
HR (1) HRP20171627T1 (da)
HU (1) HUE034902T2 (da)
LT (1) LT2838539T (da)
NO (1) NO2838539T3 (da)
PL (1) PL2838539T3 (da)
PT (1) PT2838539T (da)
RS (1) RS56595B1 (da)
RU (1) RU2627846C2 (da)
SI (1) SI2838539T1 (da)
WO (1) WO2013156329A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013030830B1 (pt) 2011-06-01 2019-12-03 Estetra S A processo para a preparação de um composto de fórmula (i) e processo de preparação de estetrol
KR101957937B1 (ko) 2011-06-01 2019-03-14 에스테트라 에스.피.알.엘. 에스테트롤 중간체의 제조 방법
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
US11638745B2 (en) * 2015-05-20 2023-05-02 University of Pittsburgh—Of the Commonwealth Cvctom of Hierher Education Method to improve neurologic outcomes in temperature managed patients
PL3106148T3 (pl) 2015-06-18 2018-08-31 Mithra Pharmaceuticals S A Jednostka dawkowania ulegająca rozpadowi w jamie ustnej zawierająca składnik estetrolowy
ES2877186T3 (es) * 2015-06-18 2021-11-16 Estetra Sprl Comprimido orodispersable que contiene estetrol
ES2877476T3 (es) 2015-06-18 2021-11-16 Estetra Sprl Comprimido orodispersable que contiene estetrol
PL3310333T3 (pl) 2015-06-18 2020-07-13 Estetra Sprl Ulegająca rozpadowi w jamie ustnej jednostka dawkowana zawierająca składnik estetrolowy
KR20220144885A (ko) 2016-08-05 2022-10-27 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 월경통 및 생리통의 관리방법
CN107260712A (zh) * 2017-06-22 2017-10-20 中国人民解放军第三军医大学 奥培米芬在制备促进髓鞘形成和再生的药物中的应用
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
CN113243332B (zh) * 2020-02-07 2023-07-28 上海市东方医院(同济大学附属东方医院) 一种广泛脑区神经元树突发育障碍动物模型的制备与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2378898A (en) * 2001-08-14 2003-02-26 Hunter Fleming Ltd Prophylactic and therapeutic use of hydroxysteroids
SI1511496T1 (sl) * 2002-06-11 2007-04-30 Pantarhei Bioscience Bv Metoda zdravljenja ali prevencije imunsko mediiranih motenj in farmacevtska formulacija za njeno uporabo
AU2003274943A1 (en) 2002-06-11 2003-12-22 Pantarhei Bioscience B.V. Use of estetrol and analogues for treating or preventing cardiovascular pathologies, in particular atherosclerosis
EP1929291A4 (en) * 2005-09-26 2010-12-22 Univ California ÖSTRIOL THERAPY FOR AUTOIMMUNE AND NEURODEGENERATIVE DISEASES AND DISEASES
US20090221540A1 (en) * 2006-01-09 2009-09-03 Pantarhei Bioscience B.V. Method of Treating An Acute Vascular Disorder
US8367647B2 (en) * 2007-06-21 2013-02-05 Pantarhei Bioscience B.V. Treatment of meconium aspiration syndrome with estrogens
AU2008325211B2 (en) * 2007-11-06 2014-11-13 Signal Coordinating Therapy, Inc. Compositions and methods for treating Parkinson's disease and related disorders
CN101884638B (zh) * 2010-07-09 2011-11-09 中山大学 5α-雄甾(烷)-3β,5,6β-三醇在制备神经元保护药物中的应用

Also Published As

Publication number Publication date
RU2627846C2 (ru) 2017-08-14
PL2838539T3 (pl) 2018-01-31
EP2838539B1 (en) 2017-08-16
EP2653163A1 (en) 2013-10-23
SI2838539T1 (sl) 2017-12-29
US20150133419A1 (en) 2015-05-14
RS56595B1 (sr) 2018-02-28
AU2013248481A1 (en) 2014-10-30
NO2838539T3 (da) 2018-01-13
EP2838539A1 (en) 2015-02-25
AU2013248481B2 (en) 2017-02-16
CY1119603T1 (el) 2018-04-04
CN104379148B (zh) 2017-08-25
HUE034902T2 (hu) 2018-03-28
HRP20171627T1 (hr) 2017-12-01
JP2015514731A (ja) 2015-05-21
LT2838539T (lt) 2017-11-27
ES2647111T3 (es) 2017-12-19
CN104379148A (zh) 2015-02-25
CA2869902C (en) 2019-07-02
WO2013156329A1 (en) 2013-10-24
US9238035B2 (en) 2016-01-19
RU2014145800A (ru) 2016-06-10
JP6139662B2 (ja) 2017-05-31
CA2869902A1 (en) 2013-10-24
PT2838539T (pt) 2017-11-15

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