DK2838539T3 - Østrogenderivater til anvendelse i behandlingen af neurologiske forstyrrelser - Google Patents

Østrogenderivater til anvendelse i behandlingen af neurologiske forstyrrelser

Info

Publication number
DK2838539T3
DK2838539T3 DK13714917.5T DK13714917T DK2838539T3 DK 2838539 T3 DK2838539 T3 DK 2838539T3 DK 13714917 T DK13714917 T DK 13714917T DK 2838539 T3 DK2838539 T3 DK 2838539T3
Authority
DK
Denmark
Prior art keywords
estrogender
derivatives
treatment
neurological disorders
neurological
Prior art date
Application number
DK13714917.5T
Other languages
English (en)
Inventor
Jean-Michel Foidart
Ekaterine Tskitishvili
Original Assignee
Univ Liege
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Liege filed Critical Univ Liege
Application granted granted Critical
Publication of DK2838539T3 publication Critical patent/DK2838539T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
DK13714917.5T 2012-04-19 2013-04-08 Østrogenderivater til anvendelse i behandlingen af neurologiske forstyrrelser DK2838539T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12164741.6A EP2653163A1 (en) 2012-04-19 2012-04-19 Estrogenic components for use in the treatment of neurological disorders
PCT/EP2013/057279 WO2013156329A1 (en) 2012-04-19 2013-04-08 Estrogenic components for use in the treatment of neurological disorders.

Publications (1)

Publication Number Publication Date
DK2838539T3 true DK2838539T3 (da) 2017-11-27

Family

ID=48050711

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13714917.5T DK2838539T3 (da) 2012-04-19 2013-04-08 Østrogenderivater til anvendelse i behandlingen af neurologiske forstyrrelser

Country Status (19)

Country Link
US (1) US9238035B2 (da)
EP (2) EP2653163A1 (da)
JP (1) JP6139662B2 (da)
CN (1) CN104379148B (da)
AU (1) AU2013248481B2 (da)
CA (1) CA2869902C (da)
CY (1) CY1119603T1 (da)
DK (1) DK2838539T3 (da)
ES (1) ES2647111T3 (da)
HR (1) HRP20171627T1 (da)
HU (1) HUE034902T2 (da)
LT (1) LT2838539T (da)
NO (1) NO2838539T3 (da)
PL (1) PL2838539T3 (da)
PT (1) PT2838539T (da)
RS (1) RS56595B1 (da)
RU (1) RU2627846C2 (da)
SI (1) SI2838539T1 (da)
WO (1) WO2013156329A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6425540B2 (ja) 2011-06-01 2018-11-21 エステトラ エス.ペ.エール.エル. エステトロール中間体を製造するための方法
RS55293B1 (sr) 2011-06-01 2017-03-31 Estetra Sprl Postupak proizvodnje intermedijara estetrola
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
US11638745B2 (en) * 2015-05-20 2023-05-02 University of Pittsburgh—Of the Commonwealth Cvctom of Hierher Education Method to improve neurologic outcomes in temperature managed patients
EP3310345B1 (en) 2015-06-18 2021-03-31 Estetra SPRL Orodispersible tablet containing estetrol
CA2988495C (en) 2015-06-18 2022-02-08 Mithra Pharmaceuticals S.A. Orodispersible dosage unit containing an estetrol component
HUE054551T2 (hu) * 2015-06-18 2021-09-28 Estetra Sprl Ösztetrolt tartalmazó, szájban diszpergálódó tabletta
CU24523B1 (es) 2015-06-18 2021-06-08 Estetra Sprl Unidad de dosificación orodispersable que contiene un componente estetrol
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
CN107260712A (zh) * 2017-06-22 2017-10-20 中国人民解放军第三军医大学 奥培米芬在制备促进髓鞘形成和再生的药物中的应用
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
CN113243332B (zh) * 2020-02-07 2023-07-28 上海市东方医院(同济大学附属东方医院) 一种广泛脑区神经元树突发育障碍动物模型的制备与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007038636A2 (en) * 2005-09-26 2007-04-05 The Regents Of The University Of California Estriol therapy for autoimmune and neurodegenerataive diseases and disorders
GB2378898A (en) * 2001-08-14 2003-02-26 Hunter Fleming Ltd Prophylactic and therapeutic use of hydroxysteroids
US7923440B2 (en) * 2002-06-11 2011-04-12 Pantarhei Bioscience B.V. Method of treating or preventing immune mediated disorders and pharmaceutical formulation for use therein
AU2003274943A1 (en) 2002-06-11 2003-12-22 Pantarhei Bioscience B.V. Use of estetrol and analogues for treating or preventing cardiovascular pathologies, in particular atherosclerosis
US20090221540A1 (en) * 2006-01-09 2009-09-03 Pantarhei Bioscience B.V. Method of Treating An Acute Vascular Disorder
WO2008156365A1 (en) * 2007-06-21 2008-12-24 Pantarhei Bioscience B.V. Treatment of meconium aspiration syndrome with estrogens
EP2214488B1 (en) * 2007-11-06 2016-12-21 Signal Coordinating Therapy, Inc. Compositions and methods for treating parkinson's disease and related disorders
CN101884638B (zh) * 2010-07-09 2011-11-09 中山大学 5α-雄甾(烷)-3β,5,6β-三醇在制备神经元保护药物中的应用

Also Published As

Publication number Publication date
US9238035B2 (en) 2016-01-19
PL2838539T3 (pl) 2018-01-31
EP2653163A1 (en) 2013-10-23
CN104379148A (zh) 2015-02-25
CY1119603T1 (el) 2018-04-04
SI2838539T1 (sl) 2017-12-29
RU2014145800A (ru) 2016-06-10
HRP20171627T1 (hr) 2017-12-01
CN104379148B (zh) 2017-08-25
AU2013248481A1 (en) 2014-10-30
RS56595B1 (sr) 2018-02-28
EP2838539B1 (en) 2017-08-16
EP2838539A1 (en) 2015-02-25
AU2013248481B2 (en) 2017-02-16
PT2838539T (pt) 2017-11-15
US20150133419A1 (en) 2015-05-14
NO2838539T3 (da) 2018-01-13
CA2869902A1 (en) 2013-10-24
JP2015514731A (ja) 2015-05-21
ES2647111T3 (es) 2017-12-19
CA2869902C (en) 2019-07-02
HUE034902T2 (hu) 2018-03-28
JP6139662B2 (ja) 2017-05-31
RU2627846C2 (ru) 2017-08-14
WO2013156329A1 (en) 2013-10-24
LT2838539T (lt) 2017-11-27

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