KR960703335A - 캡슐화된 약제(encapsulated medicine) - Google Patents
캡슐화된 약제(encapsulated medicine) Download PDFInfo
- Publication number
- KR960703335A KR960703335A KR1019950705956A KR19950705956A KR960703335A KR 960703335 A KR960703335 A KR 960703335A KR 1019950705956 A KR1019950705956 A KR 1019950705956A KR 19950705956 A KR19950705956 A KR 19950705956A KR 960703335 A KR960703335 A KR 960703335A
- Authority
- KR
- South Korea
- Prior art keywords
- dosage form
- pct
- capsule
- fluid
- surfactant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Abstract
본 발명은 실질적으로 불용성 화합물 또는 이의 염 및 캡슐내 유체, 및/또는 계면활성제 및/또는 셀룰로오스 유도체를 포함하는 캡슐화된 약학적 투여 제형에 관한 것이다. 상기 투여 제형은 캡슐 쉘에서 캡슐 내용물이 방출시, 실질적으로 불용성 화합물 또는 이의 염의 결정체 크기가 감소되기 때문에 종래의 시스템에 비해, 향상된 경구 흡수성을 제공한다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (9)
- 실질적으로 불용성 화합물 또는 이의 염 및 캡슐내 유체, 및/또는 계면활성제 및/또는 셀룰로오스 유도체를 포함하는 것을 특징으로 하는 캡슐화된 약학적 투여 제형.
- 제1항에 있어서, 실질적으로 불용성 화합물 또는 이의 염, 캡슐내 유체 및 계면활성제를 포함하는 투여 제형.
- 제1항에 있어서, 실질적으로 불용성 화합물 또는 이의 염, 캡슐내 유체 및 셀룰로오스 유도체를 포함하는 투여 제형.
- 제2항에 있어서, 캡슐내 유체가 다가 알콜인 투여 제형.
- 제3항에 있어서, 캡슐내 유체가 다가 알콜인 투여 제형.
- 제4항에 있어서, 다가 알콜이 폴리에틸렌 글리콜이고, 계면활성제가 폴리옥실 스테아레이트인 투여 제형.
- 제5항에 있어서, 다가 알콜이 폴리에틸렌 글리콜이고, 셀룰로오스 유도체가 히드록시프로필 셀룰로오스인 투여 제형.
- 제7항에 있어서, 폴리에틸렌 글리콜이 폴리에틸렌 글리콜 400이고, 히드록시프로필 셀룰로오스가 중합도가 낮은 히드록시프로필셀룰로오스인 투여 제형.
- 제8항에 있어서, 실질적으로 불용성 화합물이 닐바디핀, 3-(디플루오로매틸)-1-(4-메톡시페닐)-5-(4-메틸설포닐페닐)피라졸, 또는 3-(디플루오로메틸)-1-(4-메톡시페닐)-5-(4-메틸설피닐페닐)피라졸인 투여 제형.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16098393 | 1993-06-30 | ||
JP93-160983 | 1993-06-30 | ||
PCT/JP1994/001043 WO1995001166A1 (en) | 1993-06-30 | 1994-06-28 | Encapsulated medicine |
Publications (1)
Publication Number | Publication Date |
---|---|
KR960703335A true KR960703335A (ko) | 1996-08-17 |
Family
ID=15726345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950705956A KR960703335A (ko) | 1993-06-30 | 1994-06-28 | 캡슐화된 약제(encapsulated medicine) |
Country Status (15)
Country | Link |
---|---|
US (1) | US5683716A (ko) |
EP (1) | EP0706380B1 (ko) |
JP (1) | JPH09501150A (ko) |
KR (1) | KR960703335A (ko) |
CN (1) | CN1087933C (ko) |
AT (1) | ATE204163T1 (ko) |
AU (1) | AU682192B2 (ko) |
CA (1) | CA2165789A1 (ko) |
DE (1) | DE69427981T2 (ko) |
DK (1) | DK0706380T3 (ko) |
ES (1) | ES2161768T3 (ko) |
GR (1) | GR3036407T3 (ko) |
PT (1) | PT706380E (ko) |
TW (1) | TW360543B (ko) |
WO (1) | WO1995001166A1 (ko) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6024980A (en) * | 1996-06-28 | 2000-02-15 | Mcneil-Ppc, Inc. | Multiphase soft gelatin dosage form |
US5919481A (en) * | 1996-06-28 | 1999-07-06 | Ncneil-Ppc, Inc. | Fill material for soft gelatin pharmaceutical dosage form |
US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
WO2001060353A1 (fr) * | 2000-02-21 | 2001-08-23 | Fujisawa Pharmaceutical Co., Ltd. | Preparation liquide a absorbabilite amelioree |
US6635277B2 (en) | 2000-04-12 | 2003-10-21 | Wockhardt Limited | Composition for pulsatile delivery of diltiazem and process of manufacture |
WO2002094173A2 (en) * | 2001-05-22 | 2002-11-28 | Euro-Celtique | Tamper resistant oral dosage form |
US20030077378A1 (en) * | 2001-10-22 | 2003-04-24 | Lou Wen Chin | Hydroxypropyl cellulose encapsulation material |
NZ584729A (en) * | 2007-10-05 | 2012-12-21 | Alzheimer S Inst Of America Inc | Method for reducing amyloid deposition, amyloid neurotoxicity, and microgliosis with (-)-nilvadipine enantiomer |
JP5750278B2 (ja) * | 2011-02-28 | 2015-07-15 | 東洋カプセル株式会社 | カンデサルタンシレキセチルのカプセル充填用組成物 |
WO2014010008A1 (ja) * | 2012-07-09 | 2014-01-16 | 東洋カプセル株式会社 | カンデサルタンシレキセチルのカプセル充填用組成物 |
US11491088B2 (en) | 2012-11-06 | 2022-11-08 | CoLabs International Corporation | Compositions containing a capsule with a moisturizing agent |
US11724134B2 (en) | 2012-11-06 | 2023-08-15 | CoLabs International Corporation | Compositions containing a cellulose derived capsule with a sunscreen active agent |
US10322301B2 (en) | 2012-11-06 | 2019-06-18 | CoLabs International Corporation | Compositions containing a cellulose derived capsule with a sunscreen active agent |
US11690793B2 (en) | 2012-11-06 | 2023-07-04 | Colabs Int'l Corp. | Composition containing a cellulose derived capsule with a sunscreen |
US11707421B2 (en) | 2012-11-06 | 2023-07-25 | Colabs Int'l Corp. | Compositions containing a flexible derived capsule with an active agent |
JP2015536985A (ja) | 2012-11-06 | 2015-12-24 | コラブス インターナショナル コーポレーション | 日焼け止めを含むセルロース由来カプセル含有組成物 |
EP3813786A4 (en) | 2018-06-27 | 2022-06-29 | Colabs International Corporation | Compositions comprising silicon dioxide-based particles including one or more agents |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8507779D0 (en) * | 1985-03-26 | 1985-05-01 | Fujisawa Pharmaceutical Co | Drug carrier |
DE3636123A1 (de) * | 1986-10-23 | 1988-05-05 | Rentschler Arzneimittel | Arzneizubereitungen zur oralen verabreichung, die als einzeldosis 10 bis 240 mg dihydropyridin enthalten |
GB8629761D0 (en) * | 1986-12-12 | 1987-01-21 | Harris Pharma Ltd | Capsules |
KR920008948B1 (ko) * | 1987-02-12 | 1992-10-12 | 니혼 덴네쯔 게이기 가부시끼가이샤 | 프린트 기판의 납땜방법 및 그의 장치 |
US5340591A (en) * | 1992-01-24 | 1994-08-23 | Fujisawa Pharmaceutical Co., Ltd. | Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine |
-
1994
- 1994-06-28 US US08/569,122 patent/US5683716A/en not_active Expired - Fee Related
- 1994-06-28 CA CA002165789A patent/CA2165789A1/en not_active Abandoned
- 1994-06-28 AU AU69842/94A patent/AU682192B2/en not_active Ceased
- 1994-06-28 JP JP7503396A patent/JPH09501150A/ja not_active Ceased
- 1994-06-28 DE DE69427981T patent/DE69427981T2/de not_active Expired - Fee Related
- 1994-06-28 WO PCT/JP1994/001043 patent/WO1995001166A1/en active IP Right Grant
- 1994-06-28 ES ES94918588T patent/ES2161768T3/es not_active Expired - Lifetime
- 1994-06-28 AT AT94918588T patent/ATE204163T1/de not_active IP Right Cessation
- 1994-06-28 DK DK94918588T patent/DK0706380T3/da active
- 1994-06-28 KR KR1019950705956A patent/KR960703335A/ko not_active Application Discontinuation
- 1994-06-28 CN CN94192941A patent/CN1087933C/zh not_active Expired - Fee Related
- 1994-06-28 PT PT94918588T patent/PT706380E/pt unknown
- 1994-06-28 EP EP94918588A patent/EP0706380B1/en not_active Expired - Lifetime
- 1994-06-29 TW TW083105987A patent/TW360543B/zh active
-
2001
- 2001-08-17 GR GR20010401130T patent/GR3036407T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT706380E (pt) | 2002-02-28 |
CN1127990A (zh) | 1996-07-31 |
ES2161768T3 (es) | 2001-12-16 |
US5683716A (en) | 1997-11-04 |
JPH09501150A (ja) | 1997-02-04 |
EP0706380A1 (en) | 1996-04-17 |
GR3036407T3 (en) | 2001-11-30 |
DE69427981D1 (de) | 2001-09-20 |
EP0706380B1 (en) | 2001-08-16 |
AU682192B2 (en) | 1997-09-25 |
TW360543B (en) | 1999-06-11 |
CN1087933C (zh) | 2002-07-24 |
DE69427981T2 (de) | 2001-11-29 |
DK0706380T3 (da) | 2001-10-08 |
ATE204163T1 (de) | 2001-09-15 |
WO1995001166A1 (en) | 1995-01-12 |
AU6984294A (en) | 1995-01-24 |
CA2165789A1 (en) | 1995-01-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E601 | Decision to refuse application |