KR960700703A - 안정한 미코페놀산 함유 피부 외용제 조성물(stable mycophenolic acid-containing composition for epidermic application) - Google Patents

안정한 미코페놀산 함유 피부 외용제 조성물(stable mycophenolic acid-containing composition for epidermic application) Download PDF

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Publication number
KR960700703A
KR960700703A KR1019950703537A KR19950703537A KR960700703A KR 960700703 A KR960700703 A KR 960700703A KR 1019950703537 A KR1019950703537 A KR 1019950703537A KR 19950703537 A KR19950703537 A KR 19950703537A KR 960700703 A KR960700703 A KR 960700703A
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KR
South Korea
Prior art keywords
composition
mycophenolic acid
skin
stable
epidermic
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KR1019950703537A
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English (en)
Inventor
다꾸조 가미시다
다까시 미야자끼
Original Assignee
다꾸조 가미시다
도오교오 야꾸힝 고오교오 가부시기가이샤
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Application filed by 다꾸조 가미시다, 도오교오 야꾸힝 고오교오 가부시기가이샤 filed Critical 다꾸조 가미시다
Publication of KR960700703A publication Critical patent/KR960700703A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

크로타미톤, 살리실산 메틸 및 살리실산 글리콜으로부터 선택되는 안정제 1종 이상을 활성성분으로서 미코페놀산을 함유하는 조성물에 배합하여서 된 건선 등의 각종 피부질환 치료에 유용한 안정한 미코페놀산 함유 피부 외용제 조성물을 제공한다.

Description

안정한 미코페놀산 함유 피부 외용제 조성물(STABLE MYCOPHENOLIC ACID-CONTAINING COMPOSITION FOR EPIDERMIC APPLICATION)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 미코페놀산을 유효성분으로 하는 피부 외용제 조성물에 있어서, 크로타미톤, 살리실산 메틸 및 살리실산 글리콜로 된 군으로부터 선택되는 안정제 1종 이상을 배합한 것을 특징으로 하는 안정한 미코페놀산 함유 피부 외용제 조성물.
  2. 제1항에 있어서, 미코페놀산을 조성물 전체 중량에 대해 0.01∼5.0wt.%의 양으로 함유하는 피부 외용제 조성물.
  3. 제2항에 있어서, 미코페놀산을 조성물 전체 중량에 대해 0.01∼2.0wt.%의 양으로 함유하는 피부 외용제 조성물.
  4. 제1항∼제3항중 어느 한 항에 있어서, 크로타미톤, 살리실산 메틸 및 살리실산 글리콜로 된 군으로부터 선택되는 안정제 1종 이상을 조성물 전체 중량에 대해 1.0∼15.0wt.%의 양으로 함유하는 피부 외용제 조성물.
  5. 제1항∼제4항중 어느 한 항에 있어서, 연고제, 크리임제, 겔제, 겔크리임제, 로우션제 또는 액제로부터 선택되는 한가지 제형인 피부 외용제 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950703537A 1993-12-22 1994-12-19 안정한 미코페놀산 함유 피부 외용제 조성물(stable mycophenolic acid-containing composition for epidermic application) KR960700703A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5323851A JPH07179341A (ja) 1993-12-22 1993-12-22 安定なミコフェノール酸含有皮膚外用剤
JP93-323851 1993-12-22
PCT/JP1994/002131 WO1995017179A1 (fr) 1993-12-22 1994-12-19 Preparation dermatologique stable contenant de l'acide mycophenolique

Publications (1)

Publication Number Publication Date
KR960700703A true KR960700703A (ko) 1996-02-24

Family

ID=18159294

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950703537A KR960700703A (ko) 1993-12-22 1994-12-19 안정한 미코페놀산 함유 피부 외용제 조성물(stable mycophenolic acid-containing composition for epidermic application)

Country Status (6)

Country Link
EP (1) EP0685230A4 (ko)
JP (1) JPH07179341A (ko)
KR (1) KR960700703A (ko)
AU (1) AU669829B2 (ko)
CA (1) CA2156396A1 (ko)
WO (1) WO1995017179A1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1206937B1 (en) * 1999-07-16 2008-01-23 Shoei Co., Ltd. Nitroimidazole external preparations for the treatment of atopic dermatitis
WO2012011192A1 (ja) * 2010-07-23 2012-01-26 マルホ株式会社 タクロリムスを含有する水中油型クリーム状組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3868454A (en) * 1972-08-14 1975-02-25 Lilly Co Eli Psoriasis treatment with mycophenolic acid derivatives
JPS5815909A (ja) * 1981-07-22 1983-01-29 Toko Yakuhin Kogyo Kk 抗真菌外用剤
JPS63146817A (ja) * 1986-12-11 1988-06-18 Kao Corp 外用抗真菌剤
JPH06239740A (ja) * 1993-02-18 1994-08-30 Hiroshi Hibino ミコフェノール酸含有外用治療薬
JPH06256182A (ja) * 1993-03-05 1994-09-13 L T T Kenkyusho:Kk 外用製剤

Also Published As

Publication number Publication date
WO1995017179A1 (fr) 1995-06-29
EP0685230A4 (en) 1996-01-24
CA2156396A1 (en) 1995-06-29
EP0685230A1 (en) 1995-12-06
AU1201095A (en) 1995-07-10
JPH07179341A (ja) 1995-07-18
AU669829B2 (en) 1996-06-20

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