KR950016784A - 인터페론용작용효과증강제및 이 증강제와 인터페론을 함유하는 항비루스활성 증강조성물 - Google Patents

인터페론용작용효과증강제및 이 증강제와 인터페론을 함유하는 항비루스활성 증강조성물 Download PDF

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KR950016784A
KR950016784A KR1019940036164A KR19940036164A KR950016784A KR 950016784 A KR950016784 A KR 950016784A KR 1019940036164 A KR1019940036164 A KR 1019940036164A KR 19940036164 A KR19940036164 A KR 19940036164A KR 950016784 A KR950016784 A KR 950016784A
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South Korea
Prior art keywords
interferon
enhancer
fad
enhancing
flavin adenine
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KR1019940036164A
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English (en)
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요시로 이시와따
다까히또 조모리
히데쓰구 사이또
다까히꼬 미따니
기이찌 사와이
Original Assignee
다니모또 케이지
가부시끼가이샤 산와가가꾸겐꾸쇼
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Publication of KR950016784A publication Critical patent/KR950016784A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/407—Liver; Hepatocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Physiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

1. 청구범위에 기재된 발명이 속한 기술분야 ; 인터페론용작용효과 증강제 및 이 증강제와 인터페론을 함유하는 항비루스 활성증강조성물.
2. 발명이 해결하려고 하는 기술적 과제 ; 인터페론의 항비루스작용을 현저히 향상시켜, 본 발명의 작용증강제의 병용으로 고가의 인터페론사용량을 줄이고 B형 및 C형 만성감염에 대해 인터페론약효가 불충분한점의 개선.
3. 발명의 해결방법의 요지 ; 후라빈아데닌디누클레오티드(FAD), FAD와 돼지간장엑기스와의 혼합물, 후라빈아데닌모노클레오티드(FMN) 및 리보후라민(비타민 B2)는 어느것을 인터페론의 작용효과 증강제로 사용.
4. 발명의 중용한 용도 ; 인터페론B형 및 C형 만성간염치료제.

Description

인터페론용작용효과증강제 및 이 증강제와 인터페론을 함유하는 항비루스활성 증강조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 돼지간장엑기스와 후라빈아데닌디누클레오티드(FAD)와의 혼합물, FAD, 후라빈아데닌모노누클레오티드(FMN)및 리보후라빈(비타민 B2)의 적어도 1인 것을 특징으로 하는, 인터페론용작용효과증강제.
  2. 돼지간장엑기스와 후라빈아데닌디누클레오티드(FAD)와의 혼합물, FAD, 후라빈아데닌모노누클레오티드(FMN)및 리보후라빈(비타민 B2)의 적어도 1과, 인터페론을 함유하고, 이 인터페론이 인간유래의,및 r형 인터페론에서 선택되는 것을 특징으로 하는, 항비루스활성증강조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019940036164A 1993-12-27 1994-12-23 인터페론용작용효과증강제및 이 증강제와 인터페론을 함유하는 항비루스활성 증강조성물 KR950016784A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5332630A JPH07188052A (ja) 1993-12-27 1993-12-27 インターフェロン用作用効果増強剤及び該増強剤とインターフェロンとを含有する抗ウイルス活性増強組成物
JP93-332630 1993-12-27

Publications (1)

Publication Number Publication Date
KR950016784A true KR950016784A (ko) 1995-07-20

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ID=18257109

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940036164A KR950016784A (ko) 1993-12-27 1994-12-23 인터페론용작용효과증강제및 이 증강제와 인터페론을 함유하는 항비루스활성 증강조성물

Country Status (4)

Country Link
US (1) US5730971A (ko)
EP (1) EP0659436A1 (ko)
JP (1) JPH07188052A (ko)
KR (1) KR950016784A (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002060921A2 (en) * 2000-11-09 2002-08-08 Board Of Trustees Of The University Of Illinois Enhancement of immune response to vaccine by interferon alpha
CA2429793C (en) * 2000-11-29 2009-04-28 Morinaga Milk Industry Co., Ltd. Interferon therapeutic effect enhancer
EA013008B1 (ru) * 2007-09-05 2010-02-26 Николай Евгеньевич Шатуновский Композиции аполактоферрина и способы их применения в лечении вирусного гепатита с
JP2018131410A (ja) * 2017-02-15 2018-08-23 ヒノキ新薬株式会社 カスパーゼ−３阻害剤とその用途
CN108179151A (zh) * 2017-12-27 2018-06-19 青岛蔚蓝生物股份有限公司 一种重组猪α-干扰素、其制备方法及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53127811A (en) * 1977-04-14 1978-11-08 Nippon Netsukaritsuchi Yakuhin Treating agent for cirhosis of liver
US5550111A (en) * 1984-07-11 1996-08-27 Temple University-Of The Commonwealth System Of Higher Education Dual action 2',5'-oligoadenylate antiviral derivatives and uses thereof
JPH04200400A (ja) * 1990-11-30 1992-07-21 Sanwa Kagaku Kenkyusho Co Ltd ヒト生体由来の試料からのウイルスゲノムの抽出法及び該ウイルスゲノムの検出法
FR2674753B1 (fr) * 1991-04-02 1995-03-10 Jean Berque Nouvelles indications therapeutiques, en particulier pour le traitement du sida, d'un medicament deja existant et fabrique a partir d'une molecule denuee de contre-indications et d'effets indesirables.
FR2676648B1 (fr) * 1991-05-22 1993-09-10 Dolisos Lab Nouvelles compositions, leur procede de preparation et leurs applications comme substance active de medicament antigrippal ou antiviral.
GB9321558D0 (en) * 1993-10-19 1993-12-08 Radopath Ltd Anti-viral agents
JPH07149655A (ja) * 1993-11-29 1995-06-13 Ajinomoto Co Inc Ｎｏ合成酵素活性化剤

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Publication number Publication date
US5730971A (en) 1998-03-24
JPH07188052A (ja) 1995-07-25
EP0659436A1 (en) 1995-06-28

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