KR940002225A - 피리딘 유도체의 제조방법 - Google Patents
피리딘 유도체의 제조방법 Download PDFInfo
- Publication number
- KR940002225A KR940002225A KR1019920013031A KR920013031A KR940002225A KR 940002225 A KR940002225 A KR 940002225A KR 1019920013031 A KR1019920013031 A KR 1019920013031A KR 920013031 A KR920013031 A KR 920013031A KR 940002225 A KR940002225 A KR 940002225A
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- KR
- South Korea
- Prior art keywords
- compound
- following formula
- present
- acid catalyst
- preparing
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
본 발명은 위산분비를 억제시키는 벤조이미다졸 유도체의 제조에 사용되는, 다음 구조식(Ⅰ)의 피리딘 유도체의 제조방법에 관한 것이다.
본 발명에 따라, 다음 구조식(Ⅱ)의 디엔 화합물과 다음 구조식(Ⅲ)의 이면 화합물을 산촉매 하에서 반응시켜 다음 구조식(Ⅳ)의 피페리딘 화합물을 제조한 뒤, 알콜 용매 하에서 염기로 처리하여 방향족고리화시킴으로써 목적화합물을 제조한다.
본 발명은, 원하는 작용기가 이미 도입된 각각의 디엔 화합물과 이민 화합물을 고리화첨가반응시킴으로써, 목적화합물을 짧은 단계로 제조하는 효율적이며 더욱 진보된 제조방법을 제공한다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (2)
- 다음 구조식(Ⅱ)의 2-메틸-3-메톡시-1,3-펜타디엔과 다음 구조식(Ⅲ)의 이민 화합물을 산촉매 하에서 반응시켜 다음 구조식(Ⅳ)의 피페리딘 화합물을 제조한 뒤, 메탄올 또는 에탄올 용매 하에서 수산화바륨을 첨가하여 방향족 고리화시킴을 특징으로 하는 다음 일반식(Ⅰ)의 클로로메틸 피리딘 화합물의 제조방법.
- 제1항에 있어서, 산촉매가 사염화 티타늄, 삼불화 붕소 디에틸에테르 착물, 디에틸알루미늄 클로리드 또는 삼브롬화 붕소임을 특징으로 하는 일반식(Ⅰ)의 클로로메틸 피리딘 화합물의 제조방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019920013031A KR950008529B1 (ko) | 1992-07-22 | 1992-07-22 | 피리딘 유도체의 제조방법 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019920013031A KR950008529B1 (ko) | 1992-07-22 | 1992-07-22 | 피리딘 유도체의 제조방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR940002225A true KR940002225A (ko) | 1994-02-16 |
| KR950008529B1 KR950008529B1 (ko) | 1995-07-31 |
Family
ID=19336747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019920013031A KR950008529B1 (ko) | 1992-07-22 | 1992-07-22 | 피리딘 유도체의 제조방법 |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR950008529B1 (ko) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7024881B2 (en) | 2004-03-30 | 2006-04-11 | Samsung Electronics Co., Ltd. | Refrigerator with door handle |
| WO2021045300A1 (ko) * | 2019-09-03 | 2021-03-11 | 주식회사 위니아대우 | 냉장고 |
| KR20210107311A (ko) | 2020-02-24 | 2021-09-01 | 동국성신(주) | 코드히터와 호일을 부착하기 위한 핫프레스 공정 설비 |
-
1992
- 1992-07-22 KR KR1019920013031A patent/KR950008529B1/ko not_active IP Right Cessation
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7024881B2 (en) | 2004-03-30 | 2006-04-11 | Samsung Electronics Co., Ltd. | Refrigerator with door handle |
| WO2021045300A1 (ko) * | 2019-09-03 | 2021-03-11 | 주식회사 위니아대우 | 냉장고 |
| KR20210107311A (ko) | 2020-02-24 | 2021-09-01 | 동국성신(주) | 코드히터와 호일을 부착하기 위한 핫프레스 공정 설비 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR950008529B1 (ko) | 1995-07-31 |
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