KR930703290A - 코티닌 면역검정용 합텐, 트레이서, 면역원 및 항체 - Google Patents
코티닌 면역검정용 합텐, 트레이서, 면역원 및 항체Info
- Publication number
- KR930703290A KR930703290A KR1019930702040A KR930702040A KR930703290A KR 930703290 A KR930703290 A KR 930703290A KR 1019930702040 A KR1019930702040 A KR 1019930702040A KR 930702040 A KR930702040 A KR 930702040A KR 930703290 A KR930703290 A KR 930703290A
- Authority
- KR
- South Korea
- Prior art keywords
- nhc
- formula
- divalent radical
- hapten
- immunogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000003018 immunoassay Methods 0.000 title claims abstract 13
- 125000004076 pyridyl group Chemical group 0.000 claims abstract 13
- 230000002163 immunogen Effects 0.000 claims abstract 12
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 8
- 125000005842 heteroatom Chemical group 0.000 claims abstract 8
- 229920006395 saturated elastomer Polymers 0.000 claims abstract 8
- 239000000700 radioactive tracer Substances 0.000 claims abstract 7
- 150000001875 compounds Chemical class 0.000 claims abstract 6
- UIKROCXWUNQSPJ-VIFPVBQESA-N (-)-cotinine Chemical compound C1CC(=O)N(C)[C@@H]1C1=CC=CN=C1 UIKROCXWUNQSPJ-VIFPVBQESA-N 0.000 claims abstract 5
- UIKROCXWUNQSPJ-UHFFFAOYSA-N Cotinine Natural products C1CC(=O)N(C)C1C1=CC=CN=C1 UIKROCXWUNQSPJ-UHFFFAOYSA-N 0.000 claims abstract 5
- 229950006073 cotinine Drugs 0.000 claims abstract 5
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims abstract 3
- 238000002875 fluorescence polarization Methods 0.000 claims abstract 3
- 125000002947 alkylene group Chemical group 0.000 claims 4
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 claims 4
- 229920001308 poly(aminoacid) Polymers 0.000 claims 3
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 2
- 229940098773 bovine serum albumin Drugs 0.000 claims 2
- 125000000524 functional group Chemical group 0.000 claims 1
- 239000000523 sample Substances 0.000 abstract 3
- 239000012472 biological sample Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/641,840 | 1991-01-16 | ||
| US07/641,840 US5164504A (en) | 1991-01-16 | 1991-01-16 | Haptens, tracers, immunogens and antibodies for immunoassays for cotinine derivatives |
| PCT/US1992/000382 WO1992012975A1 (en) | 1991-01-16 | 1992-01-16 | Haptens, tracers, immunogens and antibodies for immunoassays for cotinine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR930703290A true KR930703290A (ko) | 1993-11-29 |
Family
ID=24574070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019930702040A Withdrawn KR930703290A (ko) | 1991-01-16 | 1992-01-16 | 코티닌 면역검정용 합텐, 트레이서, 면역원 및 항체 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5164504A (enExample) |
| EP (1) | EP0569490A1 (enExample) |
| JP (1) | JPH06505251A (enExample) |
| KR (1) | KR930703290A (enExample) |
| AU (1) | AU652809B2 (enExample) |
| CA (1) | CA2100265A1 (enExample) |
| WO (1) | WO1992012975A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5527686A (en) * | 1991-07-29 | 1996-06-18 | Serex, Inc. | Differential binding affinities and dissociation assays based thereon |
| US5710009A (en) * | 1994-02-17 | 1998-01-20 | Serex, Inc. | Receptor:release ligand (reland) complexes and release assays using said reland and methods and kits based thereon |
| US5840307A (en) * | 1995-03-31 | 1998-11-24 | Immulogic Pharmacuetical Corp. | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation |
| US20020032316A1 (en) * | 1995-03-31 | 2002-03-14 | Cantab Pharmaceuticals Research Limited | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same |
| EP0888552A1 (en) * | 1996-03-20 | 1999-01-07 | Serex, Inc. | Chromatographic immunoassay device and method utilizing particle valency for quantitation |
| EP1015028A2 (en) * | 1997-09-19 | 2000-07-05 | Serex, Inc. | Methods to improve immunogenicity of antigens and specificity of antibodies |
| AU7808500A (en) | 1999-10-18 | 2001-04-30 | Denis Marshall-Fraser | Sample taking device |
| GB0031079D0 (en) * | 2000-12-20 | 2001-01-31 | Smithkline Beecham Plc | Vaccine |
| EP1685138B1 (en) * | 2003-11-17 | 2009-10-14 | North Carolina State University | Regiospecific synthesis of nicotine derivatives |
| US7112678B2 (en) | 2003-11-17 | 2006-09-26 | North Carolina State University | Regiospecific synthesis of nicotine derivatives |
| WO2022243270A1 (en) | 2021-05-21 | 2022-11-24 | Philip Morris Products S.A. | Mouthpiece with capillary channel for an aerosol-generating device |
| EP4340648A1 (en) | 2021-05-21 | 2024-03-27 | Philip Morris Products S.A. | Aerosol-generating article with biomarker sensor |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61126084A (ja) * | 1984-11-26 | 1986-06-13 | Japan Tobacco Inc | ４−アミノコチニン及びその製造方法 |
| JPS61126083A (ja) * | 1984-11-26 | 1986-06-13 | Japan Tobacco Inc | ４−アミノコチニン及びその製造方法 |
-
1991
- 1991-01-16 US US07/641,840 patent/US5164504A/en not_active Expired - Fee Related
-
1992
- 1992-01-16 KR KR1019930702040A patent/KR930703290A/ko not_active Withdrawn
- 1992-01-16 CA CA002100265A patent/CA2100265A1/en not_active Abandoned
- 1992-01-16 AU AU12571/92A patent/AU652809B2/en not_active Expired - Fee Related
- 1992-01-16 EP EP92904991A patent/EP0569490A1/en not_active Withdrawn
- 1992-01-16 JP JP4505358A patent/JPH06505251A/ja active Pending
- 1992-01-16 WO PCT/US1992/000382 patent/WO1992012975A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1992012975A1 (en) | 1992-08-06 |
| AU652809B2 (en) | 1994-09-08 |
| CA2100265A1 (en) | 1992-07-17 |
| JPH06505251A (ja) | 1994-06-16 |
| AU1257192A (en) | 1992-08-27 |
| EP0569490A4 (enExample) | 1994-04-06 |
| EP0569490A1 (en) | 1993-11-18 |
| US5164504A (en) | 1992-11-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69121844D1 (de) | Immunotest für Cyclosporin | |
| ATE102948T1 (de) | Neue digoxigenin-derivate und ihre verwendung. | |
| KR910020438A (ko) | 다수염소화된 비페닐을 검출하기 위한 시약 및 방법 | |
| US8367842B2 (en) | Fluorescent dyes and uses thereof | |
| KR930703290A (ko) | 코티닌 면역검정용 합텐, 트레이서, 면역원 및 항체 | |
| KR910020036A (ko) | 펜사이클리딘 및 펜사이클리딘 대사체 검정법, 트레이서, 면역원, 항체 및 시약 키트 | |
| AU602090B2 (en) | Fluorescent conjugates and biological diagnostic assay | |
| CA2014318A1 (en) | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay | |
| FI914298A0 (fi) | Monoklonala motkroppar foer metall- katjoner och smao molekyler. | |
| ATE194339T1 (de) | Verbesserte immunoessayreagenzien zum nachweis von kannabinoiden | |
| ES2153361T3 (es) | Reactivos y procedimientos de cuantificacion de la totalidad de las doxepinas en fluidos biologicos. | |
| CA1339439C (en) | Benzodiazepines assay, tracers, immunogens and antibodies | |
| DE3483941D1 (de) | Immunofluoreszierender nachweis, zusammensetzung und verfahren. | |
| KR910020436A (ko) | 바비튜레이트 검정법, 트레이서, 면역원, 항체 및 키트 | |
| CA2117536A1 (en) | Immunological detection of organophosphates | |
| ES2152229T3 (es) | Reactivos y procedimientos de cuantificacion de la amitriptilina o de la nortriptilina en fluidos biologicos. | |
| US5939332A (en) | Phencyclidine analogs for immunoassay | |
| ES522722A1 (es) | Procedimiento de inmunoanalisis para determinar propanolol en una muestra | |
| ES2151491T3 (es) | Reactivos y procedimientos de cuantificacion de la imipramina o de la desipramina en fluidos biologicos. | |
| EP0373508A3 (en) | Barbiturate assay, tracers, immunogens and antibodies | |
| CA2114327A1 (en) | Haptens, tracers, immunogens and antibodies for immunoassays for propoxyphene | |
| WO1997024621A3 (en) | Reagents for measuring lead levels via the quantification of porphobilinogen | |
| EP0095665A1 (en) | Labelled conjugates of ethosuximide, ethosuximide immunogens, antibodies thereto, immunoassay method employing the antibodies and reagent means, test kit and test device for the immunoassay method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19930708 |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |