KR930002346A - 데카히드로-8H-이소퀴노[2, 1-g][1, 6]나프티리딘 및 데카히드로벤조[a]피롤로[2, 3-e]퀴놀리진 유도체 - Google Patents

데카히드로-8H-이소퀴노[2, 1-g][1, 6]나프티리딘 및 데카히드로벤조[a]피롤로[2, 3-e]퀴놀리진 유도체 Download PDF

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Publication number
KR930002346A
KR930002346A KR1019920012695A KR920012695A KR930002346A KR 930002346 A KR930002346 A KR 930002346A KR 1019920012695 A KR1019920012695 A KR 1019920012695A KR 920012695 A KR920012695 A KR 920012695A KR 930002346 A KR930002346 A KR 930002346A
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KR
South Korea
Prior art keywords
carbon atoms
compound
lower alkyl
pharmaceutically acceptable
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019920012695A
Other languages
English (en)
Korean (ko)
Inventor
디. 클락 로빈
스페딩 마이클
살리스버리 레드펀 윌리암
Original Assignee
앨런 크루비너
신텍스(미합중국)인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 앨런 크루비너, 신텍스(미합중국)인크. filed Critical 앨런 크루비너
Publication of KR930002346A publication Critical patent/KR930002346A/ko
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019920012695A 1991-07-17 1992-07-16 데카히드로-8H-이소퀴노[2, 1-g][1, 6]나프티리딘 및 데카히드로벤조[a]피롤로[2, 3-e]퀴놀리진 유도체 Withdrawn KR930002346A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73169191A 1991-07-17 1991-07-17
US731,691 1991-07-17

Publications (1)

Publication Number Publication Date
KR930002346A true KR930002346A (ko) 1993-02-23

Family

ID=24940584

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920012695A Withdrawn KR930002346A (ko) 1991-07-17 1992-07-16 데카히드로-8H-이소퀴노[2, 1-g][1, 6]나프티리딘 및 데카히드로벤조[a]피롤로[2, 3-e]퀴놀리진 유도체

Country Status (14)

Country Link
EP (1) EP0524004A1 (https=)
JP (1) JPH0665242A (https=)
KR (1) KR930002346A (https=)
AU (1) AU655998B2 (https=)
CA (1) CA2074038A1 (https=)
FI (1) FI923267L (https=)
HU (2) HUT61550A (https=)
IE (1) IE922314A1 (https=)
IL (1) IL102521A (https=)
IT (1) IT1256880B (https=)
NO (1) NO922812L (https=)
NZ (1) NZ243586A (https=)
TW (1) TW209219B (https=)
ZA (1) ZA925324B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2339636C2 (ru) 2003-06-20 2008-11-27 Ф.Хоффманн-Ля Рош Аг Гексагидропиридоизохинолины в качестве ингибиторов дипептидилпептидазы iv (dpp-iv)
CN103387583B (zh) 2012-05-09 2018-04-13 中国科学院上海药物研究所 二芳基并[a,g]喹嗪类化合物、其制备方法、药物组合物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791108A (en) * 1987-04-13 1988-12-13 Syntex (U.S.A.) Inc. Sulfonyl-decahydro-8H-isoquino[2,1-G][1,6]-naphthyridines and related compounds useful as α2 -blockers

Also Published As

Publication number Publication date
HU9202333D0 (en) 1992-10-28
ITTO920606A0 (it) 1992-07-16
IT1256880B (it) 1995-12-27
HUT61550A (en) 1993-01-28
AU2031392A (en) 1993-01-21
IE922314A1 (en) 1993-01-27
CA2074038A1 (en) 1993-01-18
NO922812L (no) 1993-01-18
ITTO920606A1 (it) 1994-01-16
EP0524004A1 (en) 1993-01-20
FI923267A0 (fi) 1992-07-16
ZA925324B (en) 1994-07-17
IL102521A (en) 1996-05-14
NO922812D0 (no) 1992-07-16
HU210711A9 (en) 1995-06-28
TW209219B (https=) 1993-07-11
FI923267A7 (fi) 1993-01-18
AU655998B2 (en) 1995-01-19
NZ243586A (en) 1995-03-28
FI923267L (fi) 1993-01-18
JPH0665242A (ja) 1994-03-08

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19920716

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid