KR920700028A - 감속형 스펀섬유상 시스템 및 이의 제조방법 - Google Patents

감속형 스펀섬유상 시스템 및 이의 제조방법

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KR920700028A
KR920700028A KR1019900702473A KR900702473A KR920700028A KR 920700028 A KR920700028 A KR 920700028A KR 1019900702473 A KR1019900702473 A KR 1019900702473A KR 900702473 A KR900702473 A KR 900702473A KR 920700028 A KR920700028 A KR 920700028A
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saccharide
pharmaceutical product
spun
beeswax
product
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KR1019900702473A
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KR0139107B1 (ko
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씨. 휘츠 리챠드
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씨. 휘츠 리챠드
휘츠 파마슈티칼 리미티드
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G3/368—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins, antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A21—BAKING; EDIBLE DOUGHS
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    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/02—Apparatus specially adapted for manufacture or treatment of sweetmeats or confectionery; Accessories therefor
    • A23G3/10—Candy-pulling machines ; Processes or apparatus for making cotton candy or candy floss
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
    • A61L2300/222—Steroids, e.g. corticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

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Abstract

내용 없음

Description

감속형 스펀섬유상 시스템 및 이의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (40)

  1. 약제와 적어도 하나의 삭카라이드를 함유하는 조성물(여기서, 조성물의 함량은 통상적인 실온하의 물에 가해질 때 스펀 섬유(SuPn fiber)덩어리가 소수성인 것으로 여겨지긴 하지만 물의 온도가 통상적으로 실온보다 훨씬 높아질 때 분산되어 콜로이드성 또는 콜로이드 유사성 분산액이 형성되도록 선택한다)을 용융방사시켜 약제 함유 스펀 섬유 덩어리를 제조함을 특징으로 하여, 예정된 방출 패턴을 지닌 약제학적 생성물을 제조하는 방법.
  2. 제 1 항에 있어서, 삭카라이드에 대한 약제의 비가 통상적인 실온하의 물에 높여질 때 그 안에서 신속하게 분산되는 스펀 섬유 덩어리를 생성시키는 비율을 초과하도록 조성물의 함량을 선택하는 방법.
  3. 제 2 항에 있어서, 조성물을 약제 함유 비히콜(여기서, 비히콜은 광유를 포함한다)과 삭카라이드를 배합하여 제조하는 방법.
  4. 제 1 항에 있어서, 조성물이 약제와 삭카라이드 이외에, 통상적인 실온하의 물에서는 명백한 소수성을 유발시키는 반면, 승온하에서는 분산되는 스펀 섬유 덩어리를 안정화시키는 성분을 포함하는 방법.
  5. 제 4 항에 있어서, 성분이 밀랍 및 석유 젤리로 이루어진 그룹으로부터 선택되는 방법.
  6. 용이하게 수용성인 섬유내로 방사될 수 있는 적어도 하나의 삭카라이드와 광유, 밀랍 및 이들의 혼합물로 부터 이루어진 그룹중에서 선택된 일정양의 물질을 배합한 후에 이러한 물질과 삭카라이드와 배합물을 가공하여 스펀섬유 스펀섬유 덩어리를 수득하는 단계를 포함함을 특징으로 하여 스펀 삭카라이드를 안정화하는 방법.
  7. 제 6 항에 있어서, 삭카로이드로서 슈크로즈를 사용하는 방법.
  8. 제 6 항에 있어서, 삭카로이드로서 클루코즈를 사용하는 방법.
  9. 방사가능하고 용이하게 수용성인 재료, 유효량의 약제, 및 약제와 수용성 재료 이외의 성분(이러한 성분은 스펀 섬유를 안정화시키고 물에 가해질 때 스펀 섬유가 상태로 되는 속도를 저하시킨다)으로 이루어진 섬유를 포함하는 약제학적 생성물.
  10. 제 9 항에 있어서, 성분이 밀랍인 약제학적 생성물.
  11. 제 9 항에 있어서, 성분이 광유인 약제학적 생성물.
  12. 제 9 항에 있어서, 성분이 광유, 밀랍 및 이들의 혼합물로 이루어진 그룹중에서 선택되는 약제학적 생성물.
  13. 삭카라이드와 피부학적으로 유효한 활성 성분을 함유하는 스펀 섬유 덩어리(여기서, 이러한 섬유 덩어리는 통상적으로 실온하의 물에 가해질때 삭카라이드 단독으로만 이루어진 스펀 섬유보다 느린 속도로 분산된다)를 포함하는 약제학적 생성물.
  14. 제 13 항에 있어서, 스펀 섬유가, 스펀 섬유 덩어리가 통상적인 실온하의 물에서 분산되는 것을 억제하지는 않으면서도 분산속도를 느리게 하는 물질을 포함하는 약제학적 생성물.
  15. 제 14 항에 있어서, 물질이 밀랍, 광유 및 이들의 혼합물로 이루어진 그룹으로부터 선택되는 약제학적 생성물.
  16. 제 13 항에 있어서, 활성 성분이 석유 젤리인 약제학적 생성물.
  17. 제 16 항에 있어서, 삭카라이드가 슈크로즈, 락토즈, 글루코즈 및 이들의 혼합물로 이루어진 그룹중에서 선택되는 약제학적 조성물.
  18. 제 17 항에 있어서, 삭카라이드가 슈크로즈이고 활성 성분이 석유 젤리(여기서, 슈크로즈에 대한 석유 젤리의 용적비는 1:5를 초과한다)인 약제학적 조성물.
  19. 제 13 항에 있어서, 활성 성분이 광유 비히콜과 혼합하여 항생제 성분을 포함하는 약제학적 생성물.
  20. 제 13 항에 있어서, 활성 성분이 코르티코이드 성분을 포함하고 스펀 섬유가 일정량의 광유를 추가로 포함하는 약제학적 생성물.
  21. 제 13 항에 있어서, 활성 성분이 펙틴인 약제학적 생성물.
  22. 제 21 항에 있어서, 물질이 밀랍, 광유 및 이들의 혼합물로 이루어진 그룹으로부터 선택되는 약제학적 생성물.
  23. 제 22 항에 있어서, 물질이 석유 젤리인 약제학적 생성물.
  24. 제 23 항에 있어서, 삭카라이드가 슈크로즈, 락토즈, 글루코즈 및 이들의 혼합물로 이루어진 그룹으로부터 선택되는 약제학적 생성물.
  25. 제 24 항에 있어서, 삭카라이드가 슈크로즈이고 활성 성분이 펙틴이며 물질이 석유 젤리인 약제학적 생성물(여기서, 슈크로즈에 대한 펜틴과 석유 젤리의 혼합 용적비는 1:5를 초과한다)
  26. 맛없는 성분과 동시에 구강내에 존재할 때는 불쾌한 맛을 은폐시킬 수 있고 맛도 있는, 방사가능하고 용이하게 수용성인 재료, 구강내에서의 소산 속도가 두가지 성분만이 존재할 때 용이하게 가용성인 재료의 소산 속도보다 느린 일정량의 맛없는 성분, 및 용이하게 가용성인 재료가 최소한 맛없는 성분만큼이나 오래 구강내에 잔존하게 하는 용이하게 가용성인 재료의 가용화를 지연시키기 위한 감속 물질로 이루어진 스펀 섬유를 포함하고 적어도 하나의 성분의 단독으로 도입된 경우에는 현저하게 맛이 없게 되는 구강을 통하여 도입하여 소모시키기 위한 생성물.
  27. 제 26 항에 있어서, 용이하게 수용성인 재료가 삭카라이드인 생성물.
  28. 제 27 항에 있어서, 맛없는 성분이 약제인 생성물.
  29. 제 28 항에 있어서, 감속제가 밀랍인 생성물.
  30. 제 29 항에 있어서, 약제가 필수적으로 수산화 알루미늄과 수산화 마그네슘과의 배합물인 생성물.
  31. 제 26 항에 있어서, 맛없는 성분이 약제인 생성물.
  32. 제 31 항에 있어서, 감속제가 밀랍인 생성물.
  33. 제 26 항에 있어서, 감속제가 밀랍인 생성물.
  34. 삭카라이드 및 스펀 섬유 덩어리가 통상적인 실온하의 물에서 분산되는 것을 억제하지 않으면서 분산속도를 느리게 하는 물질을 함유하는 스펀 섬유 덩어리를 포함하는 약제학적 생성물.
  35. 제 34 항에 있어서, 물질이 밀랍, 광유 및 이들의 혼합물로 이루어진 그룹으로부터 선택되는 약제학적 생성물.
  36. 제 35 항에 있어서, 삭카라이드가 슈크로즈, 락토즈, 클루코즈 및 이들의 혼합물로 이루어진 그룹으로부터 선택되는 약제학적 생성물.
  37. 방사가능하고 용이하게 수용성인 재료 및 이러한 물질 이외에, 스펀 섬유를 안정화시키고 물에 가해질 때 스펀 섬유가 분산된 상태로 되는 속도를 저하시키는 성분으로 이루어진 스펀 섬유를 포함하는 약제학적 생성물.
  38. 제 37 항에 있어서, 성분이 밀랍인 약제학적 생성물.
  39. 제 37 항에 있어서, 성분이 광유인 약제학적 생성물.
  40. 제 37 항에 있어서, 성분이 광유, 밀랍 및 이들의 혼합물로 이루어진 그룹으로부터 선택되는 약제학적 생성물.
    ※ 참고사항 : 최초 출원 내용에 의하여 공개하는 것임.
KR1019900702473A 1989-03-20 1990-02-22 조절된 방사된 섬유상 시스템 및 이의 제조방법 KR0139107B1 (ko)

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US325,643 1989-03-20
US325643 1989-03-20
US07/325,643 US5034421A (en) 1988-12-13 1989-03-20 Moderated spun fibrous system and method of manufacture
USPUS90/01003 1990-02-22
PCT/US1990/001003 WO1990011017A1 (en) 1989-03-20 1990-02-22 A moderated spun fibrous system and method of manuacture

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WO1990011017A1 (en) 1990-10-04
EP0464040A4 (en) 1992-03-11
AU5193290A (en) 1990-10-22
ES2043580T1 (es) 1994-01-01
JP2888633B2 (ja) 1999-05-10
KR0139107B1 (ko) 1998-05-15
CA2011290A1 (en) 1990-09-20
IL93564A0 (en) 1990-11-29
JPH04506059A (ja) 1992-10-22
DE69022223D1 (de) 1995-10-12
DE69022223T2 (de) 1996-02-01
AU640639B2 (en) 1993-09-02
HU221299B1 (en) 2002-09-28
US5034421A (en) 1991-07-23
IL93564A (en) 1994-05-30
EP0464040A1 (en) 1992-01-08
EP0464040B1 (en) 1995-09-06
HUT58510A (en) 1992-03-30
ZA902139B (en) 1990-12-28
CA2011290C (en) 2000-11-07
ATE127339T1 (de) 1995-09-15
HU902280D0 (en) 1991-12-30
RU2085188C1 (ru) 1997-07-27

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