KR920017649A - 엔벨로핑된 비루스 및 정자를 불활성화하는 방법 및 상기 방법에 사용하기 위한 물품 - Google Patents

엔벨로핑된 비루스 및 정자를 불활성화하는 방법 및 상기 방법에 사용하기 위한 물품 Download PDF

Info

Publication number
KR920017649A
KR920017649A KR1019910018612A KR910018612A KR920017649A KR 920017649 A KR920017649 A KR 920017649A KR 1019910018612 A KR1019910018612 A KR 1019910018612A KR 910018612 A KR910018612 A KR 910018612A KR 920017649 A KR920017649 A KR 920017649A
Authority
KR
South Korea
Prior art keywords
alkyl
betaine
amine oxide
oxide
composition
Prior art date
Application number
KR1019910018612A
Other languages
English (en)
Other versions
KR100221486B1 (ko
Inventor
비이 마이클즈 에드윈
맬라머드 대니얼
Original Assignee
원본 미기재
이이비이 마이클즈 리서어치 어소시에이츠 인코포레이팃드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 원본 미기재, 이이비이 마이클즈 리서어치 어소시에이츠 인코포레이팃드 filed Critical 원본 미기재
Publication of KR920017649A publication Critical patent/KR920017649A/ko
Priority to KR1019990005998A priority Critical patent/KR100227773B1/ko
Application granted granted Critical
Publication of KR100221486B1 publication Critical patent/KR100221486B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds containing nitrogen-to-oxygen bonds
    • A01N33/24—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds containing nitrogen-to-oxygen bonds only one oxygen atom attached to the nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/25—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
    • A01N37/20—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof containing the group, wherein Cn means a carbon skeleton not containing a ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A61L2300/208—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/408—Virucides, spermicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/452—Lubricants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

내용 없음

Description

엔벨로핑된 비루스 및 정자를 불활성화하는 방법 및 상기 방법에 사용하기 위한 물품
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 정자활력에 미치는 C31G(본 발명에 따른 조성물)의 효과 및 논옥시놀-9(N-9)의 효과를 보여주는 그래프이다.
제2도는 총 정자수에 미치는 C31G의 효과 및 논옥시놀-9(N-9)의 효과를 보여주는 그래프이다.
제3도는 정자의 평균 진행속도에 미치는 C31G의 효과 및 논옥시놀-9(N-9)의 효과를 보여주는 그래프이다.

Claims (16)

  1. 알킬-N-베타인, 알킬-N-설포베타인, 아실-N-베타인, 알킬-N-치환 아미노프로피온산 또는 알킬이미다졸리늄 베타인 또는 이의 두개 이상의 혼합물로 부터 선택되는 베타인, 및 알킬-N, N-디에틸 아민 옥사이드, 알킬-N, N-디히드록시에틸아민 옥사이드 또는 아실아미드 t-아민 옥사이드 또는 이의 두개 이상의 혼합물로부터 선택되는 아민 옥사이드 혼합물로 구성된 조성물을 엔벨로핑된 비루스의 소재지에 적용시키는 것으로 구성된, 엔벨로핑된 비루스의 활성을 저해하는 방법.
  2. 알킬-N-베타인, 알킬-N-설포베타인, 아실-N-베타인, 알킬-N-치환 아미노프로피온산 또는 알킬이미다졸리늄 베타인 또는 이의 두개 이상의 혼합물로 부터 선택되는 베타인, 및 알킬-N, N-디에틸 아민 옥사이드, 알킬-N, N-디히드록시에틸아민 옥사이드 또는 아실아미드 t-아민 옥사이드 또는 이의 두개 이상의 혼합물로부터 선택되는 아민 옥사이드 혼합물로 구성된 조성물을, 성적 활동중에 다른 사람으로부터 발산되는 체액에 노출되는 인체의 부분에 적용시키는 것으로 구성된, 성적으로 전달되는 질병을 야기시키는 비루스의 전달을 저해 하는 방법.
  3. 알킬-N-베타인, 알킬-N-설포베타인, 아실-N-베타인, 알킬-N-치환 아미노프로피온산 또는 알킬이미다졸리늄 베타인 또는 이의 두개 이상의 혼합물로 부터 선택되는 베타인, 및 알킬-N, N-디에틸 아민 옥사이드, 알킬-N, N-디히드록시에틸아민 옥사이드 또는 아실아미드 t-아민 옥사이드 또는 이의 두개 이상의 혼합물로부터 선택되는 아민 옥사이드 혼합물로 구성된 조성물을 살정제로서 사용하는 것으로 구성된, 정자의 활성을 저해하는 방법.
  4. 알킬-N-베타인, 알킬-N-설포베타인, 아실-N-베타인, 알킬-N-치환 아미노프로피온산 또는 알킬이미다졸리늄 베타인 또는 이의 두개 이상의 혼합물로 부터 선택되는 베타인, 및 알킬-N, N-디에틸아민 옥사이드, 알킬-N, N-디히드록시에틸아민 옥사이드 또는 아실아미드 t-아민 옥사이드 또는 이의 두개 이상의 혼합물로부터 선택되는 아민 옥사이드의 혼합물로 구성된 조성물을 함유하는 피임기구.
  5. 알킬-N-베타인, 알킬-N-설포베타인, 아실-N-베타인, 알킬-N-치환 아미노프로피온산 또는 알킬아미다졸리늄 베타인 또는 이의 두개 이상의 혼합물로 부터 선택되는 베타인, 및 알킬-N, N-디에틸 아민 옥사이드, 알킬-N, N-디히드록시에틸아민 옥사이드 또는 아실아미드 t-아민 옥사이드 또는 이의 두개 이상의 혼합물로부터 선택되는 아민 옥사이드 혼합물로 구성된, 비루스 감염을 치료하는 약제.
  6. 제1항 내지 제5항중 어느 한 항에 있어서, 조성물이, 저급 알킬인 C1-C3인, 알킬 N-디(저급알킬)베타인 및 알킬 N-디(저급알킬)옥사이드로 구성되는 방법 또는 기구.
  7. 제1항 내지 제6항중 어느 한 항에 있어서, 알킬 N-디(저급 알킬)베타인 및 알킬 N-디(저급알킬)아민 옥사이드가 1 : 5-5 : 1의 몰비인 방법 또는 기구.
  8. 제1항 내지 제7항중 어느 한 항에 있어서, 조성물이, 허용가능한 담체내 수용액내에서 측정될때 조성물의 pH를 4-8로 조절하기에 충분한 양으로 알킬 N-디(저급알킬)베타인, 알킬 N-디(저급알킬)아민 옥사이드 및 산으로 구성되는 방법 또는 기구.
  9. 제1항 내지 제8항중 어느 한 항에 있어서, 조성물이, 허용가능한 담체 내 성분(a) 및 (b)의 수용액내에서 측정될때 조성물의 pH를 4-8로 조절하기에 충분한 양으로 a)알킬 디메틸 글리신 ; b)알킬 디메틸 아민 옥사이드 및 c)산으로 구성된 방법 또는 기구.
  10. 제1항 내지 제9항중 어느 한 항에 있어서, 알킬 N-디(저급알킬)베타인이 코코베타인 또는 라우릴-베타인이고 알킬 N-디(저급알킬)아민 옥사이드가 코코아민 옥사이드 또는 라우라민 옥사이드인 방법 또는 기구.
  11. 제1항 내지 제3항중 어느 한 항에 있어서, 조성물이 점막에, 피부에, 질에, 무생물 표면에 적용되거나 공기 중에 분산되는 방법.
  12. 제1항 내지 제11항중 어느 한 항에 있어서, 베타인 및 아민 옥사이드 조성물이 포말, 겔, 크림, 연고, 젤리, 로션, 액체, 분무, 연무, 에어로졸 또는 와이프의 형태로 적용되거나 여기에 혼입되는 방법 또는 기구.
  13. 제1항 내지 제3항, 제5항 내지 제10항중 어느 한 항에 있어서, 조성물이 피임기구와 함께 사용되거나 여기로 혼입되는 방법.
  14. 제4항에 있어서, 조성물이, 콘돔에 적용된 윤활제로 혼입되거나, 조성물의 콘돔의 끝에 있는 저장소의 부분이고, 조성물이 피임 스폰지, 피임 필름, 지효성 기구, 좌약, 포알, 겔, 크림 또는 젤리로 혼입되는 피임기구.
  15. 알킬-N-베타인, 알킬-N-설포베타인, 아실-N-베타인, 알킬-N-치환 아미노프로피온산 또는 알킬이미다졸리늄 베타인 또는 이의 두개 이상의 혼합물로 부터 선택되는 베타인, 및 알킬-N, N-디에틸아민 옥사이드, 알킬-N, N-디히드록시에틴아민 옥사이드 또는 아실아미드 t-아민 옥사이드 또는 이의 두개이상의 혼합물로부터 선택되는 아민 옥사이드 혼합물로 구성된 관주욕.
  16. 알킬-N-베타인, 알킬-N-설포베타인, 아실-N-베타인, 알킬-N-치환 아미노프로피온산 또는 알킬 아미다졸리늄 베타인 또는 이의 두개 이상의 혼합물로 부터 선택되는 베타인, 및 알킬-N, N-디에틸 아민 옥사이드, 알킬-N, N-디히드록시에틸아민 옥사이드 또는 아실아미드 t-아민 옥사이드 또는 이의 두개이상의 혼합물로부터 선택되는 아민 옥사이드 혼합물로 구성된 와이프.
    ※ 참고사항 : 최초출원 내용에 의하여 공개되는 것임.
KR1019910018612A 1991-03-22 1991-10-22 베타인 및 아민 옥사이드를 함유하는 약제 KR100221486B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019990005998A KR100227773B1 (ko) 1991-03-22 1999-02-23 살정자제피임조성물

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/673,784 1991-03-22
US7/673,784 1991-03-22
US07/673,784 US5314917A (en) 1991-03-22 1991-03-22 Method for inactivating enveloped viruses and sperm

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1019990005998A Division KR100227773B1 (ko) 1991-03-22 1999-02-23 살정자제피임조성물

Publications (2)

Publication Number Publication Date
KR920017649A true KR920017649A (ko) 1992-10-21
KR100221486B1 KR100221486B1 (ko) 1999-09-15

Family

ID=24704111

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910018612A KR100221486B1 (ko) 1991-03-22 1991-10-22 베타인 및 아민 옥사이드를 함유하는 약제

Country Status (12)

Country Link
US (2) US5314917A (ko)
EP (2) EP0576425B1 (ko)
JP (2) JP3228928B2 (ko)
KR (1) KR100221486B1 (ko)
AP (1) AP327A (ko)
AT (2) ATE201593T1 (ko)
AU (1) AU661968B2 (ko)
CA (1) CA2106683C (ko)
DE (2) DE69132621T2 (ko)
OA (1) OA09911A (ko)
RU (1) RU2110256C1 (ko)
WO (1) WO1992016201A1 (ko)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5389676A (en) * 1991-03-22 1995-02-14 E. B. Michaels Research Associates, Inc. Viscous surfactant emulsion compositions
EP0949915A4 (en) * 1996-04-17 2001-07-04 Oklahoma Med Res Found TREATMENT OF DEMENTIA ASSOCIATED WITH AIDS VIRUS INFECTION (HIV-1) USING NITRONE-FREE RADICAL TRAPS
WO1998010744A1 (en) * 1996-09-12 1998-03-19 Simon Everard Barton Composition comprising an antiviral or antibacterial agent for preventing transmission of diseases
IT1305313B1 (it) 1998-07-17 2001-05-04 Colla Paolo 3,4 - diidro- 6- benzil-4-oxopirimidine sostituite e relativo processodi produzione e impiego nella terapia delle infezioni da hiv-1.
US6830557B2 (en) * 2000-02-17 2004-12-14 Leonard Paul Liquid foaming soap compositions and dispensing system therefor
US6545007B2 (en) 2000-11-17 2003-04-08 Idenix (Cayman) Limited Methods for inhibiting the transmission of HIV using topically applied substituted 6-benzyl-4-oxopyrimidines
US7086403B2 (en) 2000-12-05 2006-08-08 Church & Dwight Co., Inc. Condom with male genital desensitizer lubricant
US6616922B2 (en) 2001-03-27 2003-09-09 The Dial Corporation Antibacterial compositions
US6635679B2 (en) * 2001-05-14 2003-10-21 Akzo Nobel N.V. Methods and compositions for inactivating viruses
US6581775B1 (en) * 2001-08-10 2003-06-24 Garo Hagopian Method of external genital cleansing and prophylactic kit
US7544696B2 (en) * 2003-01-24 2009-06-09 Research Triangle Institute Spermicidal and/or antifungal composition and methods of using the same
US20050037508A1 (en) * 2003-08-12 2005-02-17 Juan Hernandez Microfluidic titration apparatus
US20050271643A1 (en) * 2003-08-14 2005-12-08 Iryna Sorokulova Bacterial strains, compositions including same and probiotic use thereof
AR057623A1 (es) * 2005-11-28 2007-12-05 Omega Bio Pharma H K Ltd Materiales y metodos para el tratamiento de las infecciones virales
US20080286235A1 (en) * 2006-02-28 2008-11-20 Beierle John W Jack Antimicrobials and related methods
US20090118352A1 (en) * 2007-11-07 2009-05-07 Esawtech, Ltd. Broad spectrum microbicidal and spermicidal compositions and methods
CA2887385C (en) 2011-05-26 2017-01-10 Glycoregimmune, Inc. Carrying On Business As Gri Bio, Inc. Hydroxy-substituted amino and ammonium derivatives and their medical use
EP3597634A1 (en) 2011-05-26 2020-01-22 GRI Bio, Inc. Oxygenated amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use
CA2886683A1 (en) 2011-05-26 2012-11-29 Glycoregimmune, Inc. Carrying On Business As Gri Bio, Inc. Amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use
US10188732B2 (en) 2012-08-06 2019-01-29 Biogen Ma Inc. Methods and compositions for inactivating enveloped viruses
GB201617063D0 (en) * 2016-10-07 2016-11-23 Cambridge Design Research Llp Condoms

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2169976A (en) * 1934-01-26 1939-08-15 Ig Farbenindustrie Ag Process of producing assistants in the textile and related industries
US2888383A (en) 1956-09-12 1959-05-26 Int Minerals & Chem Corp Oral prophylactic compositions comprising a betaine derivative
NL250152A (ko) 1959-04-20
US3296145A (en) * 1965-10-21 1967-01-03 Millmaster Onyx Corp Quaternary ammonium-tertiary amine oxide compositions
US4215144A (en) 1972-08-25 1980-07-29 Oxford Hill Ltd. Method of treating and controlling gingivitis
US3898186A (en) 1973-04-09 1975-08-05 Procter & Gamble Dishwashing compositions containing gel forming gelatin
US3976765A (en) 1973-11-01 1976-08-24 Colgate-Palmolive Company Antibacterial oral preparations
US4062976A (en) * 1975-12-18 1977-12-13 Michaels Edwin B Antimicrobial compositions employing certain substituted alanines and certain t-amine oxides
US4075350A (en) * 1975-12-18 1978-02-21 Michaels Edwin B Antimicrobial compositions employing certain betaines and certain amine oxides
US4183952A (en) * 1975-12-18 1980-01-15 Michaels Edwin B Antimicrobial compositions
CH600878A5 (ko) 1975-04-28 1978-06-30 Gaba Ag
US4117107A (en) 1975-10-17 1978-09-26 Noxell Corporation Method and composition for improving oral hygiene
CA1052273A (en) * 1975-12-18 1979-04-10 Edwin B. Michaels Antimicrobial compositions
US4093711A (en) 1976-08-13 1978-06-06 Noxell Corporation Oral hygiene
US4554097A (en) 1976-12-02 1985-11-19 Colgate-Palmolive Company Elastic detergent product containing anionic and amphoteric synthetic organic detergents
US4439355A (en) 1976-12-02 1984-03-27 Colgate-Palmolive Company Elastic detergent product of improved foaming power after use
US4207198A (en) 1976-12-02 1980-06-10 Colgate-Palmolive Company Elastic detergent cake of improved foaming power after use
US4130637A (en) 1977-01-31 1978-12-19 Colgate-Palmolive Company Anti-plaque agents
US4145436A (en) * 1977-11-07 1979-03-20 Michaels Edwin B Antimicrobial compositions and method for using same
FI783685A (fi) 1977-12-07 1979-06-08 Unilever Nv Tandkraemer
US4213961A (en) 1978-03-23 1980-07-22 Beecham, Inc. Oral compositions
US4209533A (en) 1979-01-25 1980-06-24 University Of Pittsburgh Antibacterial agent and method
DE3138770A1 (de) 1981-09-30 1983-04-14 Hoechst Ag, 6230 Frankfurt "haar- und koerperreinigungsmittel mit einem gehalt an alkylsulfatobetainen"
US4521827A (en) 1981-10-23 1985-06-04 Thermalloy, Inc. Heat sink mounting
US4451385A (en) 1982-03-15 1984-05-29 Colgate-Palmolive Company Agent for reducing detergent irritation to skin and eyes
US4490353A (en) 1983-07-13 1984-12-25 Colgate-Palmolive Company Antiplaque dentifrice with improved fluoride stability
DE3528209C2 (de) * 1984-08-07 1993-10-28 Fresenius Ag Desinfektionsmittel
US4839158A (en) * 1986-02-25 1989-06-13 E. B. Michaels Research Associates Inc. Process and composition for oral hygiene
DE3613944C1 (de) 1986-04-24 1987-08-13 Goldschmidt Ag Th Verfahren zur Herstellung einer hochkonzentrierten,fliess- und pumpfaehigen Betainloesung
DE3706484A1 (de) * 1987-02-27 1988-09-08 Bernhard Dr Janiak Viruzide und spermizide mit einem gehalt an quaternaeren ammoniumsalzen
US5244652A (en) 1991-03-22 1993-09-14 E. B. Michaels Research Associates, Inc. Viscous surface active composition

Also Published As

Publication number Publication date
CA2106683A1 (en) 1992-09-23
ATE176399T1 (de) 1999-02-15
AP327A (en) 1994-03-21
EP0733361A3 (en) 1996-10-23
JP3940568B2 (ja) 2007-07-04
ATE201593T1 (de) 2001-06-15
CA2106683C (en) 2002-09-24
JP2002037733A (ja) 2002-02-06
WO1992016201A1 (en) 1992-10-01
EP0733361A2 (en) 1996-09-25
AU661968B2 (en) 1995-08-17
DE69132621T2 (de) 2002-04-18
JPH06505700A (ja) 1994-06-30
AP9200370A0 (en) 1992-04-30
EP0576425B1 (en) 1999-02-03
US5314917A (en) 1994-05-24
JP3228928B2 (ja) 2001-11-12
US6297278B1 (en) 2001-10-02
RU2110256C1 (ru) 1998-05-10
EP0733361B1 (en) 2001-05-30
AU8222791A (en) 1992-10-21
EP0576425A1 (en) 1994-01-05
DE69130871T2 (de) 1999-09-23
KR100221486B1 (ko) 1999-09-15
DE69130871D1 (de) 1999-03-18
DE69132621D1 (de) 2001-07-05
OA09911A (en) 1994-09-15

Similar Documents

Publication Publication Date Title
KR920017649A (ko) 엔벨로핑된 비루스 및 정자를 불활성화하는 방법 및 상기 방법에 사용하기 위한 물품
CA1290250C (en) Antiseptic fluids
KR940005290A (ko) 생점착성 치료 조성물 및 사용방법
NO972899D0 (no) Vaginal enhets-doseringsform som kan anvendes som lokalt prevensjonsmiddel og/eller for å bekjempe seksuelt overförbare sykdommer og/eller HIV
CN101123947A (zh) 增稠的可涂布暖化型润滑剂
CN101128184A (zh) 可涂布暖化型润滑剂
US3169905A (en) Sanitizing composition and method of use
US3363624A (en) Prophylactic device
US6447490B1 (en) Vagina cleaning system for preventing pregnancy and sexually transmitted diseases
ES2090311T3 (es) Dispositivo de administracion y dosificacion resistente a la contaminacion.
FI98928C (fi) Valmiste käsien puhdistamiseen ja/tai desinfioimiseen, jota valmistetta voidaan käyttää saippuanannostelijalla
DK157113B (da) Praeparat til yverpleje og pattedesinfektion af malkekvaeg paa basis af jodholdige desinfektionsmidler og hudplejemidler
KR100227773B1 (ko) 살정자제피임조성물
WO1999003463A1 (en) Genital lubricants with zinc to reduce irritation and allergic reactions
WO2006112632A1 (en) Urethral condoms and liquid femidoms
AR013381A1 (es) Una composicion liquida acuosa de limpieza y antibacteriana y el procedimiento para prepararla
ES2523938T3 (es) Formulaciones tópicas para la prevención de una enfermedad de transmisión sexual y métodos para producir las mismas
JPS63258802A (ja) 公衆浴場用ウイルス感染防止剤
JPS63258412A (ja) ウイルスの皮膚接触感染防止用含浸，塗布剤
WO2013100788A1 (ru) Способ и набор для профилактики инфекционных заболеваний (варианты)
JP2000254201A (ja) 性交後の性器清浄衛生具
GT199300056A (es) Proceso para la elaboracion de una formulacion en gel antiviral para prevenir la transmision de virus
JP2015193541A (ja) フェラチオ行為時に使用する口腔衛生用清浄用品
Soderstrom 16. The Contraceptive Sponge RM Soderstrom, MD Clinical Professor, Department of Obstetrics and Gynecology, University of Washington
BR9902501A (pt) Camisinhas edson&#39;s

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
A107 Divisional application of patent
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20060621

Year of fee payment: 8

LAPS Lapse due to unpaid annual fee