KR910004378B1 - 페닐렌기를 갖는 스페르구알린(Spergualin)관련 화합물의 제조방법 - Google Patents
페닐렌기를 갖는 스페르구알린(Spergualin)관련 화합물의 제조방법 Download PDFInfo
- Publication number
- KR910004378B1 KR910004378B1 KR1019850001233A KR850001233A KR910004378B1 KR 910004378 B1 KR910004378 B1 KR 910004378B1 KR 1019850001233 A KR1019850001233 A KR 1019850001233A KR 850001233 A KR850001233 A KR 850001233A KR 910004378 B1 KR910004378 B1 KR 910004378B1
- Authority
- KR
- South Korea
- Prior art keywords
- group
- tad
- seryl
- diz
- chloro
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP84-38615 | 1984-03-02 | ||
| JP59038615A JPS60185758A (ja) | 1984-03-02 | 1984-03-02 | フエニレン基を有するスパガリン関連化合物およびその製造法 |
| JP38615 | 1984-03-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR850006932A KR850006932A (ko) | 1985-10-25 |
| KR910004378B1 true KR910004378B1 (ko) | 1991-06-26 |
Family
ID=12530153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019850001233A KR910004378B1 (ko) | 1984-03-02 | 1985-02-27 | 페닐렌기를 갖는 스페르구알린(Spergualin)관련 화합물의 제조방법 |
Country Status (17)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61129119A (ja) * | 1984-11-13 | 1986-06-17 | Microbial Chem Res Found | 新規免疫抑制剤 |
| JPS61165322A (ja) * | 1985-01-14 | 1986-07-26 | Microbial Chem Res Found | スパガリン類の注射用凍結乾燥製剤 |
| JPH075538B2 (ja) * | 1985-08-27 | 1995-01-25 | 財団法人微生物化学研究会 | フエニレン基を有するスパガリン関連ニトリル化合物及びその製造法 |
| JPH0742268B2 (ja) * | 1985-08-27 | 1995-05-10 | 財団法人微生物化学研究会 | フエニレン基を有するスパガリン類縁化合物及びその製造法 |
| ES2039213T3 (es) * | 1986-04-04 | 1993-09-16 | Microbial Chemistry Research Foundation | Procedimiento para producir nuevos compuestos relacionados con espergualina. |
| JP2605762B2 (ja) * | 1986-12-10 | 1997-04-30 | 武田薬品工業株式会社 | δ−ハイドロキシ−β−リジン誘導体およびその製造法 |
| JPH0794424B2 (ja) * | 1987-09-30 | 1995-10-11 | 財団法人微生物化学研究会 | 新スパガリン関連化合物およびその製造法 |
| US5061787A (en) * | 1988-06-24 | 1991-10-29 | Nippon Kayaku Kabushiki Kaisha | Novel spergualin-related compounds and compositions |
| JPH0776204B2 (ja) * | 1988-07-01 | 1995-08-16 | 寳酒造株式会社 | スパガリン類の精製法 |
| US4990536A (en) * | 1989-04-03 | 1991-02-05 | Nippon Kayaku Kabushiki Kaisha | Immunopotentiator and spergualin-related compound therefor |
| US5162581A (en) * | 1989-05-29 | 1992-11-10 | Takaru Shuzo Co., Ltd. | Crystalline deoxyspergualin, process for its preparation and suppository containing the same |
| EP0467280B1 (en) * | 1990-07-20 | 1994-09-28 | Nippon Kayaku Kabushiki Kaisha | Novel spergualin-related compound and use thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5748957A (en) * | 1980-09-08 | 1982-03-20 | Microbial Chem Res Found | Novel antibiotic bmg 162-af2, its preparation and carcinostatic agent comprising it as active ingredient |
| JPS57185254A (en) * | 1981-05-11 | 1982-11-15 | Microbial Chem Res Found | Novel carcinostatic substances and their preparation |
| JPS5862152A (ja) * | 1981-10-08 | 1983-04-13 | Microbial Chem Res Found | Ｎ−〔４−（３−アミノプロピル）アミノブチル〕−２−（ω−グアニジノ脂肪酸アミド）−２−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法 |
-
1984
- 1984-03-02 JP JP59038615A patent/JPS60185758A/ja active Granted
-
1985
- 1985-02-25 AT AT85102039T patent/ATE38512T1/de not_active IP Right Cessation
- 1985-02-25 EP EP85102039A patent/EP0153720B1/en not_active Expired
- 1985-02-25 DE DE8585102039T patent/DE3566114D1/de not_active Expired
- 1985-02-25 HU HU85692A patent/HU193085B/hu not_active IP Right Cessation
- 1985-02-27 KR KR1019850001233A patent/KR910004378B1/ko not_active IP Right Cessation
- 1985-02-27 US US06/706,312 patent/US4556735A/en not_active Expired - Fee Related
- 1985-02-28 ES ES540784A patent/ES8701720A1/es not_active Expired
- 1985-02-28 CA CA000475473A patent/CA1242452A/en not_active Expired
- 1985-03-01 IE IE518/85A patent/IE57975B1/en not_active IP Right Cessation
- 1985-03-01 AR AR299645A patent/AR241109A1/es active
- 1985-03-01 ZA ZA851567A patent/ZA851567B/xx unknown
- 1985-03-01 DK DK097485A patent/DK164855C/da not_active IP Right Cessation
- 1985-03-01 PT PT80038A patent/PT80038B/pt not_active IP Right Cessation
- 1985-03-01 AU AU39296/85A patent/AU575912B2/en not_active Ceased
- 1985-03-01 GR GR850531A patent/GR850531B/el unknown
- 1985-04-01 CN CN85101425.9A patent/CN1004351B/zh not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU3929685A (en) | 1985-09-05 |
| DK97485D0 (da) | 1985-03-01 |
| CN1004351B (zh) | 1989-05-31 |
| PT80038B (pt) | 1987-09-18 |
| AU575912B2 (en) | 1988-08-11 |
| DK164855B (da) | 1992-08-31 |
| HU193085B (en) | 1987-08-28 |
| US4556735A (en) | 1985-12-03 |
| EP0153720B1 (en) | 1988-11-09 |
| EP0153720A2 (en) | 1985-09-04 |
| ES540784A0 (es) | 1986-12-01 |
| ATE38512T1 (de) | 1988-11-15 |
| GR850531B (US06373033-20020416-M00035.png) | 1985-07-01 |
| HUT37117A (en) | 1985-11-28 |
| ZA851567B (en) | 1986-01-29 |
| IE850518L (en) | 1985-09-02 |
| DE3566114D1 (en) | 1988-12-15 |
| EP0153720A3 (en) | 1986-06-11 |
| DK97485A (da) | 1985-09-03 |
| AR241109A2 (es) | 1991-11-15 |
| PT80038A (en) | 1985-04-01 |
| KR850006932A (ko) | 1985-10-25 |
| CN85101425A (zh) | 1987-01-17 |
| ES8701720A1 (es) | 1986-12-01 |
| CA1242452A (en) | 1988-09-27 |
| JPH0254824B2 (US06373033-20020416-M00035.png) | 1990-11-22 |
| JPS60185758A (ja) | 1985-09-21 |
| DK164855C (da) | 1993-01-11 |
| IE57975B1 (en) | 1993-06-02 |
| AR241109A1 (es) | 1991-11-15 |
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| A201 | Request for examination | ||
| G160 | Decision to publish patent application | ||
| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant | ||
| FPAY | Annual fee payment |
Payment date: 19940324 Year of fee payment: 4 |
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| LAPS | Lapse due to unpaid annual fee |